HypoThermosol® Storage & Shipping Media

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HypoThermosol biopreservation media is a novel, engineered, optimized hypothermic storage and shipping media product.

Serum-free, protein-free HypoThermosol is designed to provide maximum storage and shipping stability for biologics at 2-8°C.

This proprietary, optimized formulation mitigates temperature-induced molecular cell stress responses that occur during chilling and re-warming of biologics, intermediate products, and final cell products intended for research and clinical applications.

Similar to our companion freeze media CryoStor, HypoThermosol FRS includes components that scavenge free radicals, provide pH buffering, oncotic/osmotic support, energy substrates, and ionic concentrations that balance the intracellular state at low temperatures.

Across a broad spectrum of cell and tissue types, HypoThermosol product has proven much more effective in reducing post-preservation necrosis and apoptosis as compared to commercial and home-brew isotonic and extracellular formulations. This results in greatly extended shelf life and improved post-preservation viability.

HypoThermosol meets USP <71> Sterility and USP <85> Endotoxin testing standards, and is manufactured under cGMP.

HypoThermosol is packaged in four convenient alternatives:

10mL Vial

HypoThermosol FRS 10mL Vial

Sterile vial filled with 10mL of HypoThermosol, closed with a flip top septum for needle access. Designed for initial product sampling or single-use applications.

100mL Bottle

HypoThermosol FRS 100mL Bottle

Nalgene PETG square media bottle with a screw cap, designed for applications requiring a larger volume of HypoThermosol, where repeated access to the container is not expected.

500mL Bottle

HypoThermosol FRS 500mL Bottle

Nalgene PETG square media bottle. Designed for even larger volume applications such as tissue transport and storage.

500mL IV Bag

HypoThermosol FRS 500mL IV Bag

EVA media bag with syringe and spike ports. Designed for improved aseptic technique when aliquotting HypoThermosol for multiple doses or repeated processing.


HypoThermosol FRS Product Information Sheet (PDF)

For pricing please click here.

Custom Orders

Please contact us for bulk or custom package configurations of HypoThermosol FRS.

HypoThermosol Performance Evidence

Product Part # Package/Volume Order
HypoThermosol FRS
10mL Vial
101373 1 x 10mL vial ORDER
HypoThermosol FRS
100mL Bottle
101102 1 x 100mL bottle ORDER
HypoThermosol FRS
500mL Bottle
101104 1 x 500mL bottle ORDER
HypoThermosol FRS
500mL IV Bag
101204 1 x 500mL IV bag ORDER
500mL Bottle
102104 1 x 500mL bottle ORDER

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