PRESS
RELEASE
COLLABORATIVE STUDY REPORTS ON THE BENEFITS OF
BIOLIFE’S CRYOSTOR™
OWEGO, NY – July 26, 2006 – A study presented this week at the joint international
annual meetings of the Society for Cryobiology and the Society for Low Temperature
Biology, Cryo 2006, in Hamburg Germany documented the benefits of BioLife’s
CryoStor™CS5 technology for the cryopreservation of primary human cell systems. The
study titled “The Role of Membrane-Mediated Apoptosis in Cryopreservation Failure”
was presented by Dr. John M. Baust to an international audience of thought leaders and
research scientists within the field of low temperature biology. The report focused on
both recent fundamental discoveries related to molecular-based cellular responses to
freezing as well as documenting how CryoStor™is able to modulate many of these
responses thereby improving post-preservation outcome. In the presentation, Dr. Baust
discussed his team’s recent discovery of the induction of apoptosis (gene-regulated cell
death) through cell membrane-based signaling events and how, through the modulation
of apoptosis, cryopreservation outcome can be improved. When asked about the study,
Dr. Baust stated “while we still do not know the exact mechanism of induction, the data
from this study clearly demonstrate that the cell membrane-based apoptotic receptor
pathways are actively involved with cryopreservation outcome. This is an important
finding because while the involvement of apoptosis in cryopreservation was discovered
over 5 years ago, progress into uncovering the specific mechanisms of activation has
been slow.” In relation to BioLife’s CryoStor™Dr. Baust commented “As we continue to
conduct molecular-based study into cell death associated with cryopreservation, it is
equally important for us to understand how new advanced technologies such as
CryoStor™influence these pathways. The data in this study, as well as numerous, others
continue to demonstrate that CryoStor™works through providing a more protective
environment for cells during the preservation process, reducing the detrimental stress
response of cells and thereby resulting in an overall increase in cell survival and
function.” The study was a joint effort between scientists from both BioLife and its
strategic research and development partner Cell Preservation Services, Inc.
This news release contains forward-looking statements as that term is defined in the Private
Securities Litigation Reform Act of 1995. These forward-looking statements include any
statements that relate to the intent, belief, plans or expectations of the Company or its
management, or that are not a statement of historical fact. Any forward-looking statements in
this news release are based on current expectations and beliefs and are subject to numerous
risks and uncertainties that could cause actual results to differ materially. Some of the specific
factors that could cause BioLife Solutions' actual results to differ materially are discussed in the
Company's recent filings with the Securities and Exchange Commission. BioLife Solutions
disclaims any obligation to update any forward-looking statements as a result of developments
occurring after the date of this press release.