Our Full Line of Biopreservation Products

Success in the regenerative medicine, biobanking, and drug discovery industries depends on the shelf life and viability of cells, tissues, and organs designated for research or clinical applications. We can help you be successful with best-in-class, cGMP-grade biopreservation media products that significantly extend stability and improve post-biopreservation viability and function of your biologic source material, intermediates, and final products.

CryoStor®

Optimized Freeze Media for Cells and Tissues

CryoStor cryopreservation freeze media products have been designed to mitigate temperature-induced molecular cell stress responses during freezing and thawing.

CryoStor proprietary freeze media products are intended for cryopreservation of biologics at -70 to -196°C and are based on the novel HypoThermosol formula.

All CryoStor products are pre-formulated with USP grade DMSO, a permeant solute cryoprotective agent which helps mitigate damage from the formation of intracellular ice.

Across a broad spectrum of cell types, CryoStor products have proven much more effective in reducing post-preservation necrosis and apoptosis as compared to commercial and home-brew isotonic and extracellular formulations. This enables greatly improved post-thaw cell yield, viability, and recovery.

CryoStor products meet USP <71> Sterility and USP <85> Endotoxin testing standards, and are manufactured under cGMP.

CryoStor is offered in several packages and pre-formulated with DMSO in final concentrations of 2%, 5%, and 10%

CryoStor Product Information Sheet (PDF)

VIEW PRODUCTS

BloodStor®

Optimized Biopreservation Media
for Cells and Tissues

BloodStor is a series of generic cGMP freeze media products used to cryopreserve stem cells, other cells, and cell components isolated from umbilical cord blood, peripheral blood, bone marrow, and other biologics. BloodStor products meet USP <71> Sterility and USP <85> Endotoxin testing standards, and are manufactured under cGMP.

VIEW PRODUCTS

HypoThermosol® FRS

Hypothermic Storage and Shipping Media

HypoThermosol biopreservation media is a novel, engineered, optimized hypothermic storage and shipping media product.

Serum-free, protein-free HypoThermosol is designed to provide maximum storage and shipping stability for biologics at 2-8°C.

This proprietary, optimized formulation mitigates temperature-induced molecular cell stress responses that occur during chilling and re-warming of biologics, intermediate products, and final cell products intended for research and clinical applications.

Similar to our companion freeze media CryoStor, HypoThermosol FRS includes components that scavenge free radicals, provide pH buffering, oncotic/osmotic support, energy substrates, and ionic concentrations that balance the intracellular state at low temperatures.

Across a broad spectrum of cell and tissue types, HypoThermosol product has proven much more effective in reducing post-preservation necrosis and apoptosis as compared to commercial and home-brew isotonic and extracellular formulations. This results in greatly extended shelf life and improved post-preservation viability.

HypoThermosol meets USP <71> Sterility and USP <85> Endotoxin testing standards, and is manufactured under cGMP.

VIEW PRODUCTS

Cell Thawing Media
10% Dextran 40

Media for Thawing Human Cells and Tissues Following Cryopreservation

BioLife’s Cell Thawing Media products are manufactured per cGMP guidelines, using USP components, and are subject to release criteria including USP <71> Sterility and USP <85> Endotoxin testing standards, as well as pH, osmolality, and appearance for no visible particulates. For research use only.

VIEW PRODUCTS

PrepaStor®

Preparation, Flush, and Transition Media

PrepaStor is an optimized flush (15-25°C) media that enables improved preservation of cells, tissues and organs. PrepaStor has been formulated as a flush solution designed to rinse culture media and “native” fluids from cell systems prior to suspension in preservation media. This variant has been shown to be effective for preparing (rinse and flushing) mammalian cells, tissues and organs.

VIEW PRODUCTS

All BioLife biopreservation media products are:

  • cGMP Manufactured
  • Formulated with USP or highest available grade components
  • Serum-Free
  • Protein-Free
  • Animal Origin-Free
  • Sterility tested per USP
  • Endotoxin tested per USP
  • Tested for pH, appearance, and biopreservation efficacy via cell-based assay

Partial List of Biologics Preserved with BioLife Products:

  • Amniotic epithelial cells
  • Avulsed teeth
  • Blood vessels
  • Bone marrow
  • Caco-2
  • Cancer stem cells
  • Cardiomyocytes
  • CHO cells
  • Chondrocytes
  • Cord blood stem cells
  • Cornea
  • Corneal epithelial cells
  • Dendritic cells
  • Dental pulp stem cells
  • Dermal papilla cells
  • Endometrial repair cells
  • Endothelial cells
  • Glial cells
  • HEK
  • Hepatocytes
  • Hybridomas
  • iPSC
  • Islet cells
  • Liver tissue
  • Lymphocytes (EBV transformed, T, T-reg)
  • McCoy cells
  • MDCK
  • Mesenchymal stem cells
  • Neuronal cells
  • Pancreatic tissue
  • PBMC
  • PC-3
  • Placental stem cells
  • Progenitor cells
  • Red blood cells
  • Renal cells
  • Skeletal myoblasts
  • Smooth muscle cells
  • Synthetic skin
  • Tissue fibroblasts
  • Umbilical cord tissue stem cells