Impact of mRNA chemistry and manufacturing process on innate immune activation

Nelson, J., Sorensen, E. W., Mintri, S., Rabideau, A. E., Zheng, W., Besin, G., Khatwani, N., Su, S. V., Miracco, E. J., Issa, W. J., Hoge, S., Stanton, M. G. and Joyal, J. L.  Impact of mRNA chemistry and manufacturing process on innate immune activation.  Science Advances. 2020; 6(26), eaaz6893.  doi: 10.1126/sciadv.aaz6893