SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms

Wang, Y., Mohseni, M., Grauel, A., Diez, J. E., Guan, W., Liang, S., Choi, J. E., Pu, M., Chen, D., Laszewski, T., Schwartz, S., Gu, J., Mansur, L., Burks, T., Brodeur, L., Velazquez, R., Kovats, S., Pant, B., Buruzula, G., Deng, E., Chen, J. T., Sari-Sarraf, F., Dornelas, C., Varadarajan, M., Yu, H., Liu, C., Lim, J., Hao, H., Jiang, X., Malamas, A., LaMarche, M. J., Geyer, F. C., McLaughlin, M., Costa, C., Wagner, J., Ruddy, D., Jayaraman, P., Kirkpatrick, N. D., Zhang, P., Iartchouk, O., Aardalen, K., Cremasco, V., Dranoff, G., Engelman, J. A., Silver, S., Wang, H., Hastings, W. D. and Goldoni, S.  SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms.  Scientific Reports. 2021; 11(1). doi: 10.1038/s41598-021-80999-x.  doi: 10.1038/s41598-021-80999-x