Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs

Won, T., Wood, M. K., Hughes, D. M., Talor, M. V., Ma, Z., Schneider, J., Skinner, J. T., Asady, B., Goerlich, E., Halushka, M. K., Hays, A. G., Kim, D., Parikh, C. R., Rosenberg, A. Z., Coppens, I., Johns, R. A., Gilotra, N. A., Hooper, J. E., Pekosz, A. and Čiháková, D. Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs. Ebiomedicine. 2022; 75, 103812. doi: 10.1016/j.ebiom.2022.103812