Wali, G., Siow, SF, Liyanage, E., Kumar, KR, Mackay-Sim, A. and Sue, CM. Reduced Acetylated Α-Tubulin In Spast Hereditary Spastic Paraplegia Patient Pbmcs. Frontiers in Neuroscience, 2023:17:1073516. Mar-23.

Holicek, P., Truxova, I., Rakova, J., Salek, C., Hensler, M., Kovar, M., Reinis, M., Mikyskova, R., Pasulka, J., Vosahlikova, S., Remesova, H., Valentova, I., Lysak, D., Holubova, M., Kaspar, P., Prochazka, J., Kasikova, L., Spisek, R., Galluzzi, L., and Fucikova, J. Type I Interferon Signaling In Malignant Blasts Contributes To Treatment Efficacy In Aml Patients. Cell Death and Disease, 2023:14:209. Mar-23.

McAuley, GE, Yiu, G., Chang, PC, Newby, GA, Campo-Fernandez, B., Fitz-Gibbon, ST, Wu, X., Kang, S-H L, Garibay, A., Butler, J., Christian, V., Wong, RL, Everette, KA, Azzun, A., Gelfer, H., Seet, CS, Narendran, A., Murguia-Favela, L., Romero, Z., Wright, N., Liu, DR, Crooks, GM, Kohn, DB. Human T Cell Generation Is Restored In Cd3Δ Severe Combined Immunodeficiency Through Adenine Base Editing. Cell, 2023:186:7, 1398-1416. Mar-23.

Quijano, JC, Wedeken, L., Ortiz, JA, Zook, HN, LeBon, JM, Luo, A., Rawson, J., Tremblay, JR, Mares, JM, Lopez, K., Chen, M-H, Jou, K., Mendez-Dorantes, C., Al-Abdullah, IH, Thurmond, DC, Kandeel, F., Riggs, AD, and Ku, HT. Methylcellulose Colony Assay And Single-Cell Micro-Manipulation Reveal Progenitor-Like Cells In Adult Human Pancreatic Ducts. Stem Cell Reports, 2023:18, 1-18. Mar-23.

Puig-Saus, C., Sennino, B., Peng, S., Wang, CL, Pan, Z., Yuen, B., Purandare, B., An, D., Quach, BB, Nguyen, D., Xia, H., Jilani, S., Shao, K., McHugh, C., Greer, J., Peabody, P., Nayak, S., Hoover, J., Said, S., Jacoby, K., Dalmas, O., Foy, SP, Conroy, A., Yi, MC, Shieh, C., Lu, W., Heeringa, K., Ma, Y., Chizari, S., Pilling, MJ, Ting, M., Tunuguntla, R., Sandoval, S., Moot, R., Hunter, T., Zhao, S., Saco, JD, Perez-Garcilazo, I., Medina, E., Vega-Crespo, A., Baselga-Carretero, I., Abril-Rodriguez, G., Cherry, G., Wong, DJ, Hundal, J., Chmielowski, B., Speiser, DE, Bethune, MT, Bao, XR, Gros, A., Griffith, OL, Griffith, M., Heath, JR, Franzusoff, A., Mandl, SJ, Ribas, A. Neoantigen-Targeted Cd8+ T Cell Responses With Pd-1 Blockade Therapy. Nature, 2023. Mar-23.

Jimeno, A., Baranda, J., Iams, J.W., Park, J.C., Mita, M., Gordon, M.S., Taylor, M. Dhani, N., Leal, A.D., Neupane, P. Eng, C., Yeku, O., Mita, A., Moser, J.C., Butler, M., Loughhead, S.M., Jennings, J. Miselis, N.R., Ji, R-R, Nair, N., Kornacker, M., Zwirtes, R.F., Bernstein, H., Sharei, A. Phase 1 Study To Determine The Safety And Dosing Of Autologous Pbmcs Modified To Present Hpv16 Antigens (Sqz-Pbmc-Hpv) In Hla-A*02+ Patients With Hpv16+ Solid Tumors. Investigational New Drugs, 2023. May-23.

Rhiel M., Geiger K., Andrieux G., Rositzka J., Boerries M., Cathomen T. and Cornu T.I. T-Cast: An Optimized Cast-Seqpipeline For Talen Confirmssuperior Safety And Efficacy Ofobligate-Heterodimeric Scaffolds. Frontiers in Genome Editing, 2023:5:1130736. Feb-23.

Danielli, S.G., Porpiglia, E., De Micheli, A.J., Navarro, N., Zellinger, M.J., Bechtold, I., Kisele, S., Volken, L., Marques, J.G., Kasper, S., Bode, P.K., Henssen, A.G., Gürgen, D., Delattre, O., Surdez, D., Roma, J., Bühlmann, P., Blau, H.M., Wachtel, M., Schäfer, B.W. Single-Cell Profiling Of Alveolar Rhabdomyosarcoma Reveals Ras Pathway Inhibitors As Cell-Fate Hijackers With Therapeutic Relevance. Science Advances, 2023:9:6. Feb-23.

Wynn, L. , Wilson, M.G. , Leonforte, C. Manufacturing Of Cd34 + Hpc-Enriched, High-Purity Mononuclear Cell Products From Umbilical Cord Blood. Cell Tissue Bank, 2023: Feb 3. Feb-23.

Mitchell, C.A., Verovskaya, E.V., Calero-Nieto, F.J., Olson, O.C., Swann, J.W., Wang, X., Hérault, A., Dellorusso, P.V., Zhang, S.Y., Svendsen, A.F., Pietras, E.M., Bakker, S.T., Ho, T.T., Göttgens, B. & Passegué, E. Stromal Niche Inflammation Mediated By Il-1 Signalling Is A Targetable Driver Of Haematopoietic Ageing. Nature Cell Biology, 2023: 25, 30–41. Jan-23.

Depuydt, M.A.C., Schaftenaar, F.H., Prange, K.H.M., Boltjes, A., Hemme, E., Delfos, L., de Mol, J., de Jong, M.J.M., Bernabé Kleijn, M.N.A., Peeters, J.A.H.M., Goncalves, L., Wezel, A., Smeets, H.J., de Borst, G.J., Foks, A.C., Pasterkamp, G., de Winther, M.P.J., Kuiper, J., Bot, I. & Slütter, B. Single-Cell T Cell Receptor Sequencing Of Paired Human Atherosclerotic Plaques And Blood Reveals Autoimmune-Like Features Of Expanded Effector T Cells. Nature Cardiovascular Reseearch, 2023. Jan-23.

Vitanza1 N.A., Wilson, A.L., Huang, W., Seidel, K., Brown, C., Gustafson, J.A., Yokoyama, J.K., Johnson, A.J., Baxter, B.A., Koning, R.W., Reid, A.N., Meechan, M., Biery, M.C., Myers, C., Rawlings-Rhea, S.D., Albert, C.M., Browd, S.R., Hauptman, J.S., Lee, A., Ojemann, J.G., Berens, M.E., Dun, M.D., Foster, J.B., Crotty, E.E., Leary, S.E.S., Cole, B.L., Perez, F.A., Wright, J.N., Orentas, R.J., Chour, T., Newell, E.W., Whiteaker, J.R., Zhao, L., Paulovich, A.G., Pinto, N., Gust, J., Gardner, R.A., Jensen, M.C., and Park, J.R. Intraventricular B7-H3 Car T Cells For Diffuse Intrinsic Pontine Glioma: Preliminary First-In-Human Bioactivity And Safety. Cancer Discovery, 2023: 13:114–31. Oct-22.

Jae-Seung Moon 1,2,11, Shady Younis 1,2,3,11, Nitya S. Ramadoss1,2,
Radhika Iyer 1,2, Khushboo Sheth 1,2, Orr Sharpe1,2, Navin L. Rao4,
Becart, S., Carman, J.A., James, E.A., Buckner, J.H., Deane, K.D., Holers, V.M., Goodman, S.M., Donlin, L.T., Davis, M.M., & Robinson, W.H. Cytotoxic Cd8+ T Cells Target Citrullinated Antigens In Rheumatoid Arthritis. Nature Communications, 2023:4:319. Jan-23.

Li, Q, Yang, C., Tian, H., Jiang, J., Li, P., Zhu, X., Lei, T., Yin, R., Ding, P., Bai, P., Li, Q. Development Of A Personalized Dendritic Cell Vaccine And Single-Cell Rna Sequencing-Guided Assessment Of Its Cell Type Composition. Cytotherapy, 2023:25:210-219. Dec-22.

Liao, J., Chen, S., Hsiao, S., Jiang, Y., Yang, Y., Zhang, Y., Wang, X., Lai, Y., Bauer, D.E., Wu, Y. Therapeutic Adenine Base Editing Of Human Hematopoietic Stem Cells. Nature Communications, 2023:14:207. Jan-23.

Dreyzin, A., Panch, S.R., Shalabi, H., Yates, B., Highfill, S.L., Jin, P., Stroncek, D., and Shah, N.N. Cryopreserved Anti-Cd22 And Bispecific Anti-Cd19/22 Car T Cells Are As Effective As Freshly Infused Cells. Molecular Therapy: Methods & Clinical Development, 2023:28:51. Dec-22.

Matlock, A.D., Vaibhav,V., Holewinski, R., Venkatraman,V., Dardov, V., Manalo, D-M., Shelley, B., Ornelas, L., Banuelos, M., Mandefro, B., Escalante-Chong, R., Li, J., Finkbeiner, S., Fraenkel, E., Rothstein, J., Thompson, L., Sareen, D., Svendsen, C.N., NIH NeuroLINCS Consortium & Van Eyk, J.E. Neurolincs Proteomics: Defining Human-Derived Ipsc Proteomes And Protein Signatures Of Pluripotency. Nature Scientific Data, 2023:10:24. Jan-23.

Follin, B., Hoeeg, C., Hunter, I., Bentsen, S., Juhl, M., Jensen, J.K., Binderup, T., Nielsen, C.H., Ripa, R.S., Kastrup, J.; Ekblond, A., and Kjaer, A. [68Ga]Ga-Nodaga-E[(Crgdyk)]2 And [64Cu]Cu-Dotatate Pet Predict Improvement In Ischemic Cardiomyopathy. Diagnostics, 2023:13:268. Jan-23.

Sypecka, M., Bzinkowska, A., Sulejczak, D., Dabrowski, F., Sarnowska, A. Evaluation Of The Optimal Manufacturing Protocols And Therapeutic Properties Of Mesenchymal Stem/Stromal Cells Derived From Wharton’S Jelly. International Journal of Molecular Sciences, 2023:24:652. Dec-22.

Skurikhin, E.G., Pershina, O.; Ermakova, N., Pakhomova, A., Zhukova, M., Pan, E., Sandrikina, L., Widera, D., Kogai, L., Kushlinskii, N., Kubatiev, A., Morozov, S.G., and Dygai, A. Cell Therapy With Human Reprogrammed Cd8+ T-Cells Has Antimetastatic Effects On Lewis Lung Carcinoma In C57Bl/6 Mice. International Journal of Molecular Sciences, 2022:23:15780. Dec-22.

Fujii, S., Endo, K., Ozeki, N., Sakamaki, Y., Kohno, Y., Mizuno, M., Katano, H., Tsuji, K., Koga, H. and Sekiya, I. Comparison Of Adhesion Of Thawed And Cultured Synovial Mesenchymal Stem Cells To The Porcine Meniscus And The Relevance Of Cell Surface Microspikes. BMC Molecular and Cell Biology, 2022:23:53. Dec-22.

Lynggaard, C.D., Jersie-Christensen, R., Juhl , M., Jensen, S.B., Grønhøj, C., Melchiors, J., Jacobsen, S., Møller-Hansen, M., Herly, M., Ekblond, A., Kastrup, J., Fischer-Nielsen, A., Belstrøm, D. & von Buchwald, C. Intraglandular Mesenchymal Stem Cell Treatment Induces Changes In The Salivary Proteome Of Irradiated Patients. Comminciations Medicine, 2022:2:160. Dec-22.

Rosinski, J.R., Raasch, L.E., Tiburcio, P.B., Breitbach, M.E., Shepherd, P.M., Yamamoto, K., Razo, E., Krabbe, N.P., Bliss, M.I., Richardson, A.D., Einwalter, M.A., Weiler, A.M., Sneed, E.L., Fuchs, K.B., Zeng, X., Noguchi, K.K., Morgan, T.K., Alberts, A.J., Antony, K.M., Kabakov, S., Ausderau, K.K., Bohm, E.K., Pritchard,J.C., Spanton, R.V, Ver Hoove, J.N., Kim, C.B.Y., Nork, T.M., Katz, A.W., Rasmussen, C.A., Hartman, A., Mejia, A., Basu, P., Simmons, H.A., Eickhoff, J.C., Friedrich, T.C., Aliota, M.T., Mohr, E.L., Dudley, D.M., O’Connor, D.H. &, Newman, C.M. Frequent First-Trimester Pregnancy Loss In Rhesus Macaques Infected With African-Lineage Zika Virus. Dec-22.

Hansen SB, Højgaard LD, Kastrup J, Ekblond A, Follin B and Juhl M. Optimizing An Immunomodulatory Potency Assay For Mesenchymal Stromal Cell. Frontiers in Immunology, 2022,13:1085312. Dec-22.

Cooper, A, Sidaway, A., Chandrashekar, A., Latta, E., Chakraborty, K., Yu, J., McMahan, K., Giffin, V., Manickam, C., Kroll, K., Mosher, M., Reeves, R.K., Gam, R., Arthofer, E., Choudhry, M., Henley, T., and Barouch, D.H. A Genetically Engineered, Stem-Cell-Derived Cellular Vaccine. Cell Reports Medicine. 2022, 3:100843. Dec-22.

Nettersheim, F.S., Armstrong , S.S., Durant, C., Blanco‑Dominguez, R., Roy, P., Orecchioni, M., Suryawanshi, V, Ley, K. Titration Of 124 Antibodies Using Cite-Seq On Human Pbmcs. Scientific Reports. 2022, 12:20817. Dec-22.

Keller, A-L., Greis, D., Eybe, J., Plöger, S., Weiss, M., Koch, A., Brucker, S.Y., Schenke-Layland, K., Schmees, C. Generation And Characterization Of Three Induced Pluripotent Stem Cells Lines From An 86-Year Old Female Individual Diagnosed With An Invasive Lobular Mammary Carcinoma. Dec-22.

Berber, P., Bondarenko, S., Michaelis, L., Weber, B.H.F. Transient Retention Of Photoreceptor Outer Segments In Matrigel-Embedded Retinal Organoids. International Journal of Molecular Sciences. 2022, 23:14893. Nov-22.

Lee, J.-H., Park, H.-J., Kim, Y.-A., Lee, D.-H., Noh, J.-K., Jung, J.-G., Yoon, H.-H., Lee, S.-K., Lee, S. Establishment Of A Serum-Free Hepatocyte Cryopreservation Process For The Development Of An “Off-The-Shelf” Bioartificial Liver System. Bioengineering. 2022, 9:738. Nov-22.

Bibby,J.A., Agarwal, D., Freiwald, T., Kunz, N., Merle, N.S., West, E.E., Larochelle, A., Chinian, F., Mukherjee, S., Afzali, B., Kemper, C., Zhang, N.R. Systematic Single Cell Pathway Analysis (Scpa) Reveals Novel Pathways Engaged During Early T Cell Activation. Feb-22.

Chua, K.J., Ling, H., Hwang, I.Y., Lee, H.L., March, J.C., Lee, Y.S., and Chang, M.W. An Engineered Probiotic Produces A Type Iii Interferon Ifnl1 And Reduces Inflammations In In Vitro Inflammatory Bowel Disease Models. Nov-22.

Najafabadi, M.G., Gray, G.K., Kong, L.R., Gupta, K., Perera, D., Brugge, J.S., Venkitaraman, A., Shehata, M. A Transcriptional Response To Replication Stress Selectively Expands A Subset Of Brca2-Mutant Mammary Epithelial Cells. Nov-22.

Khan, S., Salisch, N.C., Gil, A.I., Boedhoe, S., Feddes-de Boer, K., Serroyen, J., Schuitemaker, H., and Zahn, R.C. Sequential Use Of Ad26-Based Vaccine Regimens In Nhp To Induce Immunity Against Different Disease Targets. npj Vaccines. 2022; 7:146. Nov-22.

Sureshchandra, S., Chan, C.N., Robino, J.J., Parmelee, L.K., Nash, M.J., Wesolowski, S.R., Pietras, E.M., Friedman, J.E., Takahashi, D., Shen, W., Jiang,, X., Hennebold, J.D., Goldman, D., Packwood, W., Lindner, J.R., Roberts, Jr., C.T., Burwitz,B.J., Messaoudi, I., and Varlamov, O. Maternal Western-Style Diet Remodels The Transcriptional Landscape Of Fetal Hematopoietic Stem And Progenitor Cells In Rhesus Macaques. Stem Cell Reports. 2022, 17 :1–15. Nov-22.

Jung, N., Park, S., Kong, T., Park, H., Seo, W.M., Lee, S., Kang, K-S. Lc-Ms/Ms-Based Serum Proteomics Reveals A Distinctive Signature In A Rheumatoid Arthritis Mouse Model After Treatment With Mesenchymal Stem Cells. PLoS ONE. 2022, 17(11): e0277218. Nov-22.

Siddharth Subham, S., Jeppson, J.D., Worcester, C., Schatmeyer, B., Zhao, Madan, R., Lakis, N., Kimler, B., McGuirk, J.P., Chen, R.C.C., Stecklein, S.R., Akhavan, D. Egfr As A Potent Car T Target In Triple Negative Breast Cancer Brain Metastases. Nov-22.

Noorman, F., Rijnhout, T.W.H., de Kort, B., Hoencamp, R. Frozen For Combat: Quality Of Deep-Frozen Thrombocytes, Produced And Used By The Netherlands Armed Forces 2001–2021. Transfusion. 2022, 1–14. Nov-22.

Ravindranathan, S., Passang, T., Li, J-M, Wang, S., Dhamsania, R., Ware, M.B., Zaidi, M.Y., Zhu, J., Cardenas, M., Liu, Y., Gumber, S., Robinson, B., Sen-Majumdar, A., Zhang, H., Chandrakasan, S., Kissick, H., Frey, A.B., Thomas, S.N., El-Rayes, B.F., Lesinski, G.B. & Waller, E.K. Targeting Vasoactive Intestinal Peptidemediated Signaling Enhances Response To Immune Checkpoint Therapy In Pancreatic Ductal Adenocarcinoma. Nature Communications. 2022, 13:6418. Oct-22.

Rodenburg, L.W., Delpiano, L.; Railean, V., Centeio, R., Pinto, M.C., Smits, S.M.A., van derWindt, I.S., van Hugten, C.F.J., van Beuningen, S.F.B., Rodenburg, R.N.P., van der Ent, C.K., Amaral, M.D. , Kunzelmann, K., Gray, M.A., Beekman, J.M., and Amatngalim, G.D. Drug Repurposing For Cystic Fibrosis: Identification Of Drugs That Induce Cftr-Independent Fluid Secretion In Nasal Organoids. International Journal of Molecular Sciences. 2022, 23:12657. Oct-22.

Rabold, K., Zoodsma, M., Grondman, I., Kuijpers, Y., Bremmers, M., Jaeger, M., Zhang, B., Hobo, W., Bonenkamp, de Wilt, H.J.W., Janssen, M.J.R., Cornelissen, L.A.M., Ivan Engen-vanGrunsven, I.C.H., Mulder, W.J.M., Smit, J.W.A., Adema, G.J., Netea, M.G., Li, Y., Xu, C-J, & Netea-Maier, R.T. Reprogramming Of Myeloid Cells And Their Progenitors In Patients With Non-Medullary Thyroid Carcinoma. Nature Communications. 2022, 13:6149. Oct-22.

Kumar, S. & Meneghel, J. Optimizing And Standardizing The Cryopreservation Of Cellular Samples: New Data And Insights From The Uk’S Advanced Therapy Treatment Centres Network Programme. Cell & Gene Therapy Insights. 2022, 8:6:967–976. Oct-22.

Cunningham, A.W., Jones, M., Frank, N., Sethi, D, Miller, M.M. Stem-Like Memory T Cells Are Generated During Hollow Fiber Perfusion-Based Expansion And Enriched After Cryopreservation In An Automated Modular Cell Therapy Manufacturing Process. Cytotherapy. 2022, 24;1148-1157. Oct-22.

Fleck, J.S., Jansen, S.M.J., Wollny, D., Zenk, F., Seimiya, M., Jain, A., Okamoto, R., Santel, M., He, Z., Camp, J.G. & Treutlein, B. Inferring And Perturbing Cell Fate Regulomes In Human Brain Organoids. Nature. 2022, 1476-4687. Oct-22.

Yang, S.J., Singh, A.K., Drow, T., Tappen, T., Honaker, Y., Barahmand-Pour-Whitman, F., Linsley, P.S., Cerosaletti, K., Mauk, K., Xiang, Y., Smith, J., Mortensen, E., Cook, P.J. , Sommer, K. , Khan, I., Liggitt, D., Rawlings, D.J. , Buckner, J.H. Pancreatic Islet-Specific Engineered Tregs Exhibit Robust Antigen-Specific And Bystander Immune Suppression In Type 1 Diabetes Models. Science Translational Medicine. 2002, 14:665, eabn1716. Oct-22.

Brezinger-Dayan, K., Itzhaki, O., Melnichenko, J., Kubi, A., Zeltzer, L., Jacoby, E., Avigdor, A., Shapira Frommer, R. and Besser, M.J. Impact Of Cryopreservation On Car T Production And Clinical Response. Frontiers in Oncology. 2022, 12:1024362. Oct-22.

Skurikhin, E.G., Ermakova, N., Zhukova, M., Pershina, O., Pan, E., Pakhomova, A., Kogai, L., Goldberg, V., Simolina, E., Skurikhina, V, Widera, D. , Kubatiev, A., Morozov, S.G., Kushlinskii, N., and Dygai, A. Analysis Of Circulating Tumor And Cancer Stem Cells Provides New Opportunities In Diagnosis And Treatment Of Small Cell Lung Cancer. International Journal of Molecular Sciences. 2022, 23:10853. Sep-22.

Juhl, M., Follin, B., Christensen, J.P., Kastrup, J., Ekblond, A. Functional In Vitro Models Of The Inhibitory Effect Of Adipose Tissue-Derived Stromal Cells On Lymphocyte Proliferation: Improved Sensitivity And Quantification Through Flow Cytometric Analysis. Journal of Immunological Methods. 2022, 510:113360, ISSN 0022-1759. Sep-22.

An, Z. , Gicobi, J.K., Harrington, S.M., Zhang, H., Xu, T. , Hirdler , J., Lohse, C. , Leibovich, B.C., Dong, H., Lucien, F. Discovery Of A Novel Monoclonal Pd-L1 Antibody H1A That Promotes T-Cell Mediated Tumor Killing Activity In Renal Cell Carcinoma. Sep-22.

Najimi, M , Michel, S., Binda, M.M. , Gellynck, K., Belmonte, N., Mazza, G., Gordillo, N. , Vainilovich, Y., and Sokal, E. Human Allogeneic Liver-Derived Progenitor Cells Significantly Improve Nafld Activity Score And Fibrosis In Late-Stage Nash Animal Model. Cells. 2022, 11:2854. Sep-22.

Good, Z., Spiegel, J.Y., Sahaf, B., Malipatlolla, M.B., Ehlinger, Z.J., Kurra, S., Desai, M.H., Reynolds, W.D., Lin, A.W., Vandris, P., Wu, F., Prabhu, S., Hamilton, M.P., Tamaresis, J.S., Hanson, P.J., Patel, S., Feldman, S.A., Frank, M.J., Baird, J.H., Muffly, L., Claire, G.K., Craig, J., Kong, K.A., Wagh, D., Coller, J. Bendall, S.C., Plevritis, S.K., Miklos, D.B., Mackall, C.L. Post-Infusion Car T Reg Cells Identify Patients Resistant To Cd19-Car Therapy. Nature Medicine. 2022, 28:1860–1871. Sep-22.

Su, T., Duran, G.E., Kwang, A.C., Ramchurren, N., Fling, S.P., Kim, Y.H., & Khodadoust, M.S. Single-Cell Rna-Sequencing Reveals Predictive Features Of Response To Pembrolizumab In Sézary Syndrome. OncoImmunology. 2022, 11:1, e2115197. Aug-22.

Michaels, Y.S., Edgar, J.M., Major, M.C., Castle, E.L., Zimmerman, C., Yin, T., Hagner, A., Lau, C., Hsu, H.H., Ibañez-Rios, M.I., Durland, L.J., Knapp, D.J.H.F., Zandstra, P.W. Dll4 And Vcam1 Enhance The Emergence Of T Cell–Competent Hematopoietic Progenitors From Human Pluripotent Stem Cells. Science Advances. 2022, 8, eabn5522. Aug-22.

Cutrupi, A.N., Narayanan, R.K., Perez-Siles, G. , Grosz, B.R. , Lai, K., Boyling, A., Ellis, M., Lin, R. CY, Neumann , B., Mao, D., Uesugi, M., Nicholson, G.A., Vucic, S., Saporta, M.A., Kennerson, M.L. Novel Gene-Intergenic Fusion Involving Ubiquitin E3 Ligase Ube3C Causes Distal Hereditary Motor Neuropathy: A New Mechanism For Motor Neuron Degeneration. Aug-22.

Obach, D., Solastie, A., Liedes, O., Vara, S., Krzyżewska‐Dudek, E., Brinkmann, L., Haveri, A., Hammer, C.C., Dub, T., Meri, S., Freitag, T.L., Lyytikäinen, O., Melin, M. Impaired Immunity And High Attack Rates Caused By Sars‐Cov‐2 Variants Among Vaccinated Long‐Term Care Facility Residents. Immunity, Inflammation and Disease. 2022, 10:e679. Aug-22.

Palmer, C.D., Rappaport, A.R., Davis, M.J., Hart, M.G., Scallan, C.D., Hong, S-J, Gitlin, L., Kraemer, L.D., Kounlavouth, S., Yang, A., Smith, L., Schenk, D., Skoberne, M., Taquechel, K., Marrali, M., Jaroslavsky,J.R., Nganje, C.N., Maloney, E., Zhou, R., Navarro-Gomez, D., Greene, A.C., Grotenbreg, G., Greer, R., Blair, W., Cao, M.D., Chan, S., Bae, K., Spira, A.I., Roychowdhury, S., Carbone, D.P., Henick, B.S., Drake, C.G., Solomon, B.J., Ahn, D.H., Mahipal, A., Maron, S.B., Johnson, B., Rousseau, R., Yelensky, R., Liao, C-Y, Catenacci, D.V.T., Allen, A, Ferguson, A.R., and Jooss, K. Individualized, Heterologous Chimpanzee Adenovirus And Self-Amplifying Mrna Neoantigen Vaccine For Advanced Metastatic Solid Tumors: Phase 1 Trial Interim Results. Nature Medicine. 2022, 28:1619–1629. Aug-22.

Jachiet, V., Ricard, L., Hirsch, P., Malard, F., Pascal, L., Beyne-Rauzy, O., Peterlin, P., Maria, A., Vey, N., D’Aveni, M., Gourin, M. P., Dimicoli-Salazar, S., Banos, A., Wickenhauser, S., Terriou, L., De Renzis, B., Durot, E., Natarajan-Ame, S., Vekhoff, A., Voillat, L. Reduced Peripheral Blood Dendritic Cell And Monocyte Subsets In Mds Patients With Systemic Inflammatory Or Dysimmune Diseases . Clinical and Experimental Medicine. 2022, 10:1007. Aug-22.

Wang, F., Han, Y., Sang, W., Wang, L., Liang, X., Wang, L., Xing, Q., Guo, Y., Zhang, J., Zhang, L., Zukela, T., Xiaokereti, J., Lu, Y., Zhou, X. , Tang, B., and Li, Y. In Vitro Drug Screening Using Ipsc-Derived Cardiomyocytes Of A Long Qt-Syndrome Patient Carrying Kcnq1 & Trpm4 Dual Mutation: An Experimental Personalized Treatment. Cells. 2022, 11: 2495. Aug-22.

Raasch, L.E., Yamamoto, K., Newman, C.M., Rosinski, J.R., Shepherd, P.M., Razo, E., Crooks, C.M., Bliss, M.I., Breitbach, M.E., Sneed, E.L., Weiler, A.M., Zeng, X., Noguchi, K.K., Morgan, T.K., Fuhler, N.A., Bohm, E.K., Alberts, A.J., Havlicek, S.J., Kabakov, S., Mitzey, A.M., Antony, K.M., Ausderau, K.K., Mejia, A., Basu, P., Simmons, H.A., Eickhoff, J.C., Aliota,M.T., Mohr, E.L., Friedrich, T.C., Golos, T.G., O’ConnorI, D.H., Dudley, D.M. Fetal Loss In Pregnant Rhesus Macaques Infected With High-Dose African-Lineage Zika Virus. PLOS Neglected Tropical Diseases. 2022, 16(8): e0010623. Aug-22.

Proics, E., David, M., Mojibian, M., Speck, M., Lounnas-Mourey, N., Govehovitch, A., Baghdadi, W., Desnouveaux, J., Bastian, H., Freschi, L., Privat, G., Pouzet, C., Grossi, M., Heimendinger, P., Abel, T., Fenard, D., Levings, M.K., Meyer, F., and Dumont, C. Preclinical Assessment Of Antigen-Specific Chimeric Antigen Receptor Regulatory T Cells For Use In Solid Organ Transplantation. Gene Therapy. 2022. Aug-22.

Möller, L., Aird, E.J., Schröder, M.S., Kobel, L., Kissling, L., van de Venn, L., & Corn, J.E. Recursive Editing Improves Homology-Directed Repair Through Retargeting Of Undesired Outcomes. Nature Communications. 2022, 13:4550. Aug-22.

Amatngalim, G.D. , Rodenburg, L.W., Aalbers, B.L., Raeven, H.H.M. , Aarts, E.M., Sarhane, D., Spelier, S., Lefferts, J.W., Silva, I.A., Nijenhuis,W. , Vrendenbarg, S., Kruisselbrink, E., Brunsveld, J.E., van Drunen, C.M., Michel, S., de Winter-de Groot, K.M., Heijerman, H.G., Kapitein, L.C., Amaral, M.D., van der Ent, C.K., Beekman, J.M. Measuring Cystic Fibrosis Drug Responses In Organoids Derived From 2D Differentiated Nasal Epithelia. Life Science Alliance. 2022, 5:12, e202101320. Aug-22.

Zhou, B., Shi, X., Tang, X., Zhao, Q., Wang, L., Yao, F., Hou, Y., Wang, X., Feng, W., Wang, L., Sun, X., Wang, L., and Hu, S. Functional Isolation, Culture And Cryopreservation Of Adult Human Primary Cardiomyocytes. Signal Transduction and Targeted Therapy. 2022, 7:254. Jul-22.

Hensler, M., Rakova, J., Kasikova, L, Lanickova, T., Pasulka, J., Holicek, P., Hraska, M., Hrnciarova, T., Kadlecova, P., Schoenenberger, A., Sochorova, K., Rozkova, D., Sojka, L., Drozenova, J., Laco, J., Horvath, R., Podrazil, M., Hongyan, G., Brtnicky, T., Halaska, M.J., Rob, L., Ryska, A., Coosemans, A., Vergote, I., Garg, A.D., Cibula, D., Bartunkova, J., Spisek, R., & Fucikova, J. Peripheral Gene Signatures Reveal Distinct Cancer Patient Immunotypes With Therapeutic Implications For Autologous Dc-Based Vaccines. OncoImmunology. 2022, 11:1, e2101596 . Jul-22.

Gao, L., Wang, F., Wang, Y., Hu, L., and Mao, J. A Protocol For The Generation Of Patient-Specific Ipsc Lines From Peripheral Blood Mononuclear Cells. STAR Protocols. 2022, 3:101530. Jul-22.

Mizrahi, R.A. , Lin, W.Y., Gras, A., Niedecken, A.R., Wagner, E.K., Keating, S.M., Ikon, N., Manickam, V.A., Asensio, M.A., Leong, J., Medina-Cucurella, A.V., Benzie, E., Carter, K.P., Chiang , Y., Edgar, R.C. , Leong , R., Lim , Y.W. , Simons, J.F., Spindler, M.J., Stadtmiller, K., Wayham , N., Büscher, D., Terencio, J.V., Di Germanio, C., Chamow, S.M., Olson, C., Pino, P.A., Park, J-G, Hicks, A., Ye, C., Garcia-Vilanova , A. , Martinez-Sobrido, L., Torrelles, J.B. , Johnson, D.S., and Adler, A.S. Gmp Manufacturing And Ind-Enabling Studies Of A Recombinant Hyperimmune Globulin Targeting Sars-Cov-2. Pathogens. 2022, 11:806. Jul-22.

Swift, M., Horns, F., and Quake, S.R. Fate Bias And Transcriptional Memory Of Human B Cells. Jul-22.

D’haese, S. , Laeremans, T., den Roover, S., Allard, S.D. , Vanham, G., Aerts, J.L. Efficient Induction Of Antigen-Specific Cd8+ T-Cell Responses By Cationic Peptide-Based Mrna Nanoparticles. Pharmaceutics. 2022, 14, 1387. Jul-22.

Gupta, R., Vanlieshout E., Mainion K., Bonilla D., Kim M., Muñoz-Grajales, C., Nassar, C., Johnson S. R., Hiraki L.T., Ahmad, Z., Touma, Z., Bookman, A., Wither, J.E. Altered Balance Of Pro-Inflammatory Immune Cells To T Regulatory Cells Differentiates Symptomatic From Asymptomatic Invididuals With Anti-Nuclear Antibodies. Frontiers in Immunology. 2022; 13:886442. Jun-22.

Gooch, A., Zhang, P., Hu, Z., Son, N. L., Avila, N., Fischer, J., Roberts, G., Sellon, R., Westenfelder, C. First Report On The Effective Intraperitoneal Therapy Of Insulin-Dependent Diabetes Mellitus In Pet Dogs Using “Neo-Islets,” Aggregates Of Adipose Stem And Pancreatic Islet Cells. bioRxiv pre-print on line 6/10/19. Jun-19.

Lynn, R. C., Weber, E. W., Gennert, D., Sotillo, E., Xu, P., Good, Z., Anbunathan, H., Jones, R., Tieu, V., Granja, J., DeBourcy, C., Majzner, R., Satpathy, A. T., Quake, S. R., Chang, H., Mackall, C. L. C-Jun Overexpressing Car-T Cells Are Exhaustion-Resistant And Mediate Enhanced Antitumor Activity. bioRxiv pre-print on line 5/29/19. May-19.

Ding, J., Adiconis, X., Simmons, S. K., Kowalczyk, M. S., Hession, C. C., Marjanovic, N. D., Hughes, T. K., Wadsworth, M. H., Burks, T., Nguyen, L. T., Kwon, J. Y. H., Barak, B., Ge, W., Kedaigle, A. J., Carroll, S., Li, S., Hacohen, N., Rozenblatt-Rosen, O., Shalek, A. K., Villani, A., Regev, A., Levin, J. Z. Systematic Comparative Analysis Of Single Cell Rna-Sequencing Methods. bioRxiv pre-print on line 5/9/19. May-19.

Buchheit, K. M., Dwyer, D. F., Ordovas-Montanes, J., Katz, H. R., Lewis, E., Bhattacharyya, N., Shalek, A. K., Barrett, N. A., Boyce, J. A., Laidlaw, T. M. Il-5Rα Marks Nasal Polyp Igg4 And Ige-Secreting Cells In Aspirin-Exacerbated Respiratory Disease. Jan-00.

Webber, B. R., Lonetree, C., Kluesner, M. G., Johnson, M. J., Pomeroy, E. J., Diers, M. D., Lahr, W. S., Draper, G., Slipek, N. J., Lovendahl, K. N., McElroy, A., Gordon, W. R., Osborn, M. J., Moriarity, B. S. Highly Efficient Multiplex Human T Cell Engineering Without Double-Strand Breaks Using Cas9 Base Editors. bioRxiv pre-print on line 11/29/18. Nov-18.

Rao, D. A., Berthier, C. C., Arazi, A., Davidson, A., Liu, Y., Browne, E. P., Eisenhaure, T. M., Chicoine, A., Lieb, D. J., Smilek, D. E., Tosta, P., Lederer, J. A., Brenner, M. B., Hildeman, D., Woodle, E. S., Wofsy, D., Anolik, J. H., Kretzler, M., Hacohen, N. and Diamond, B. A Protocol For Single-Cell Transcriptomics From Cryopreserved Renal Tissue And Urine For The Accelerating Medicine Partnership (Amp) Ra/Sle Network. bioRxiv pre-print on line 3/5/18. Mar-18.

Priceman, S. J., Gerdts, E. A., Tilakawardane, D., Kennewick, K. T., Murad, J. P., Park, A. K., Jeang, B., Yamaguchi, Y., Yang, X., Urak, R., Weng, L., Chang, W., Wright, S., Pal, S., Reiter, R. E., Wu, A. M., Brown, C. E. and Forman, S. J. Co-Stimulatory Signaling Determines Tumor Antigen Sensitivity And Persistence Of Car T Cells Targeting Psca+ Metastatic Prostate Cancer. Oncoimmunology. 2017; 7(2), e1380764. Oct-17.

Robinson, M., Chapani, P., Styan, T., Vaidyanathan, R. and Willerth, S. M. Functionalizing Ascl1 With Novel Intracellular Protein Delivery Technology For Promoting Neuronal Differentiation Of Human Induced Pluripotent Stem Cells. Stem Cell Reviews And Reports. August 2016; 12(4), 476-483. May-16.

Slamecka, J., Salimova, L., McClellan, S., van Kelle, M., Kehl, D., Laurini, J., Cinelli, P., Owen, L., Hoerstrup, S. P. and Weber, B. Non-Integrating Episomal Plasmid-Based Reprogramming Of Human Amniotic Fluid Stem Cells Into Induced Pluripotent Stem Cells In Chemically Defined Conditions. Cell Cycle. 2016; 15(2), 234-249. Jan-16.

Raynaud, C. M., Halabi, N., Elliott, D. A., Pasquier, J., Elefanty, A. G., Stanley, E. G. and Rafii, A. Human Embryonic Stem Cell Derived Mesenchymal Progenitors Express Cardiac Markers But Do Not Form Contractile Cardiomyocytes. Plos ONE. 2013; 8(1), e54524. Jan-13.

Ross, S. B., Fraser, S. T., Nowak, N. and Semsarian, C. Generation Of Induced Pluripotent Stem Cells (Ipscs) From A Hypertrophic Cardiomyopathy Patient With The Pathogenic Variant P.Val698Ala In Beta-Myosin Heavy Chain ( Myh7 ) Gene. Stem Cell Research. 2017; 20, 88-90. Mar-17.

Ross, S. B., Fraser, S. T., Bagnall, R. D. and Semsarian, C. Peripheral Blood Derived Induced Pluripotent Stem Cells (Ipscs) From A Female With Familial Hypertrophic Cardiomyopathy. Stem Cell Research. 2017; 20, 76-79. Mar-17.

Halaidych, O. V., Freund, C., van den Hil, F., Salvatori, D. C., Riminucci, M., Mummery, C. L. and Orlova, V. V. Inflammatory Responses And Barrier Function Of Endothelial Cells Derived From Human Induced Pluripotent Stem Cells. Stem Cell Reports. 2018; 10(5), 1642-1656. May-18.

Grima, J. C., Daigle, J. G., Arbez, N., Cunningham, K. C., Zhang, K., Ochaba, J., Geater, C., Morozko, E., Stocksdale, J., Glatzer, J. C., Pham, J. T., Ahmed, I., Peng, Q., Wadhwa, H., Pletnikova, O., Troncoso, J. C., Duan, W., Snyder, S. H., Ranum, L. P., Thompson, L. M., Lloyd, T. E., Ross, C. A. and Rothstein, J. D. Mutant Huntingtin Disrupts The Nuclear Pore Complex. Neuron. 2017; 94(1), 93-107.e6. Apr-17.

Guinan, E. C., Cole, G. A., Wylie, W. H., Kelner, R. H., Janec, K. J., Yuan, H., Oppatt, J., Brennan, L. L., Turka, L. A. and Markmann, J. Ex Vivo Costimulatory Blockade To Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation. American Journal Of Transplantation. 2016; 16(7), 2187-2195 .Jan-16.

Dunn, K., and Palecek, S. Engineering Scalable Manufacturing Of High-Quality Stem Cell-Derived Cardiomyocytes For Cardiac Tissue Repair. Frontiers In Medicine. 2018; 5:110. Apr-18.

Miere, C., Devito, L., and Ilic, D..Sendai. Virus-Based Reprogramming Of Mesenchymal Stromal/Stem Cells From Umbilical Cord Wharton’S Jelly Into Induced Pluripotent Stem Cells. Methods In Molecular Biology. 2014; Vol 1357, 33-44. Aug-15.

Sarugaser R, Ennis J, Stanford WL, Davies JE. Isolation, Propagation, And Characterization Of Human Umbilical Cord Perivascular Cells (Hucpvcs). Jan-00.

Chamith Y. Fonseka, Deepak A. Rao, Nikola C. Teslovich, Susan K. Hannes, Kamil Slowikowsi, Michael F. Gurish, Laura T. Donlin, Michael E. Weinblatt, Elena M. Massarotti, Jonathan S. Coblyn, Simon M. Helfgott, Derrick J. Todd, Vivian P. Bykerk,
Elizabeth W. Karlson, Joerg Ermann, Yvonne C. Lee, Michael B. Brenner, and Soumya Raychaudhuri. Reverse Association Of Single Cells To Rheumatoid Arthritis Accounting.
For Mixed Effects Identifies An Expanded Cd27- Hla-Dr+ Effector Memory
Cd4+ T Cell Population. Aug-17.

Charlesworth, C., Deshpande, P., Dever, D., Dejene, B., Gomez-Ospina, N., & Mantri, S., Pavel-Dinu, M., Camarena, J., Weinberg, K. I., Porteus, M. H. Identification Of Pre-Existing Adaptive Immunity To Cas9 Proteins In Humans.

Preininger MK, Singh M, Xu C. Cryopreservation Of Human Pluripotent Stem Cell-Derived Cardiomyocytes: Strategies, Challenges, And Future Directions. Adv Exp Med Biol. 2016;951:123-135. Nov-16.

Domingues, S., Darle, A., Masson, Y., Saidani, M., Lagoutte, E., Bejanariu, A., Coutier, J., Ayata, R. E., Bouschbacher, M., Peschanski, M., Lemaitre, G. and Baldeschi, C. Clinical Grade Human Pluripotent Stem Cell-Derived Engineered Skin Substitutes Promote Keratinocytes Wound Closure In Vitro. Cells. 2022; 11(7), 1151. doi: 10.3390/cells11071151

Iwata, Y., Narushima, Y., Harada, A. and Mishima, M. Priming treatment with T-cell redirecting bispecific antibody ERY974 reduced cytokine induction without losing cytotoxic activity in vitro by changing the chromatin state in T cells. Toxicology And Applied Pharmacology. 2022; 441, 115986. doi: 10.1016/j.taap.2022.115986

Thongsin, N. and Wattanapanitch, M. A three-dimensional immune-oncology model for studying in vitro primary human NK cell cytotoxic activity. PLOS ONE. 2022; 17(3), e0264366. doi: 10.1371/journal.pone.0264366

Aisha Naeem, Nikita Gupta, Natasha Arzoo, Usra Naeem, Muhammad Jawad Khan, Muhammad Umer Choudhry, Wanxing Cui and Chris Albanese. A Survey and Critical Evaluation of Isolation, Culture, and Cryopreservation Methods of Human Amniotic Epithelial Cells. Cell Cycle. 2022. doi: 10.1080/15384101.2021.2020015

Olivarria, G. M., Cheng, Y., Furman, S., Pachow, C., Hohsfield, L. A., Smith-Geater, C., Miramontes, R., Wu, J., Burns, M. S., Tsourmas, K. I., Stocksdale, J., Manlapaz, C., Yong, W. H., Teijaro, J., Edwards, R., Green, K. N., Thompson, L. M. and Lane, T. E. Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice. Journal Of Virology. 2022; 96(4). doi: 10.1128/jvi.01969-21

DeVeaux, S. A., Ogle, M. E., Vyshnya, S., Chiappa, N. F., Leitmann, B., Rudy, R., Day, A., Mortensen, L. J., Kurtzberg, J., Roy, K. and Botchwey, E. A. Characterizing human mesenchymal stromal cells’ immune-modulatory potency using targeted lipidomic profiling of sphingolipids. Cytotherapy. 2022. doi: 10.1016/j.jcyt.2021.12.009

Capelli, C., Frigerio, S., Lisini, D., Nava, S., Gaipa, G., Belotti, D., Cabiati, B., Budelli, S., Lazzari, L., Bagnarino, J., Tanzi, M., Comoli, P., Perico, N., Introna, M. and Golay, J. A comprehensive report of long-term stability data for a range ATMPs: A need to develop guidelines for safe and harmonized stability studies. Cytotherapy. 2022. doi: 10.1016/j.jcyt.2021.12.004

Vogelzang, N. J., Beer, T. M., Gerritsen, W., Oudard, S., Wiechno, P., Kukielka-Budny, B., Samal, V., Hajek, J., Feyerabend, S., Khoo, V., Stenzl, A., Csöszi, T., Filipovic, Z., Goncalves, F., Prokhorov, A., Cheung, E., Hussain, A., Sousa, N., Bahl, A., Hussain, S., Fricke, H., Kadlecova, P., Scheiner, T., Korolkiewicz, R. P., Bartunkova, J., Spisek, R., Stadler, W., Berg, A. S., Kurth, K., Higano, C. S., Aapro, M., Krainer, M., Hruby, S., Meran, J., Polyakov, S., Machiels, J., Roumeguere, T., Ackaert, K., Lumen, N., Gil, T., Minchev, V., Tomova, A., Dimitrov, B., Koleva, M., Juretic, A., Fröbe, A., Vojnovic, Z., Drabek, M., Jarolim, L., Buchler, T., Kindlova, E., Schraml, J., Zemanova, M., Prausova, J., Melichar, B., Chodacka, M., Jansa, J., Daugaard, G., Delonchamps, N., Duclos, B., Culine, S., Deplanque, G., Le Moulec, S., Hammerer, P., Rodemer, G., Ritter, M., Merseburger, A., Grimm, M., Damjanoski, I., Wirth, M., Burmester, M., Miller, K., Herden, J., Keck, B., Wuelfing, C., Winter, A., Boegemann, M., von Schmeling, I. K., Fornara, P., Jaeger, E., Bodoky, G., Pápai, Z., Böszörményi-Nagy, G., Vanella, P., SotoParra, H., Passalacqua, R., Ferrau, F., Maio, M., Fratino, L., Cortesi, E., Purkalne, G., Asadauskiene, J., Janciauskiene, R., Tulyte, S., Cesas, A., Polee, M., Haberkorn, B., van de Eertwegh, F., van den Berg, P., Beeker, A., Nieboer, P., Zdrojowy, R., Staroslawska, E., Fijuth, J., Sikora-Kupis, B., Karaszewska, B., Fernandes, I., Sousa, G., Rodrigues, T., Dzamic, Z., Babovic, N., Cvetkovic, B., Sokol, R., Mikuláš, J., Gajdos, M., Brezovsky, M., Mincik, I., Breza, J., Arranz, J. A., Calvo, V., Rubio, G., Chapado, M. S., Boreu, P. G., Montesa, A., Olmos, D., Mellado, B., Castellano, D., Puente, J., Karlsson, E. T., Ahlgren, J., Pandha, H., Mazhar, D., Vilarino-Varela, M., Elliott, T., Pedley, I., Zarkar, A., Law, A., Slater, D., Karlin, G., Bilusic, M., Redfern, C., Gaur, R., McCroskey, R., Clarkson, D., Agrawal, M., Shtivelband, M., Nordquist, L., Karim, N., Hauke, R., Flaig, T., Jhangiani, H., Singal, R., Choi, B., Reyes, E., Corman, J., Hwang, C., Appleman, L., McClay, E., Fleming, M., Gunuganti, V., Cheung, E., Gartrell, B., Sartor, A., Williamson, S., Gandhi, J., Schnadig, I., Burke, J., Bloom, S., Shore, N., Mayer, T., Oh, W., Bryce, A., Belkoff, L., Vaishampayan, U., Agarwala, S., Kucuk, O., Agrawal, A., Walsh, W., Poiesz, B., Harshman, L., Dawson, N. and Sharma, S. Efficacy and Safety of Autologous Dendritic Cell–Based Immunotherapy, Docetaxel, and Prednisone vs Placebo in Patients With Metastatic Castration-Resistant Prostate Cancer – The VIABLE Phase 3 Randomized Clinical Trial. JAMA Oncology. 2022. doi: 10.1001/jamaoncol.2021.7298

Fear, V. S., Forbes, C. A., Anderson, D., Rauschert, S., Syn, G., Shaw, N., Jamieson, S., Ward, M., Baynam, G. and Lassmann, T. CRISPR single base editing, neuronal disease modelling and functional genomics for genetic variant analysis: pipeline validation using Kleefstra syndrome EHMT1 haploinsufficiency. Stem Cell Research & Therapy. 2022; 13(1). doi: 10.1186/s13287-022-02740-3

Bifani, A. M., Tan, H. C., Choy, M. M., and Ooi, E. E. Cell Strain-Derived Induced Pluripotent Stem Cells as an Isogenic Approach To Investigate Age-Related Host Response to Flaviviral Infection. Journal of Virology. 2022; 96(3). doi: 10.1128/jvi.01737-21

Haider, P., Hoberstorfer, T., Salzmann, M., Fischer, M. B., Speidl, W. S., Wojta, J. and Hohensinner, P. J. Quantitative and Functional Assessment of the Influence of Routinely Used Cryopreservation Media on Mononuclear Leukocytes for Medical Research. International Journal Of Molecular Sciences. 2022; 23(3), 1881. doi: 10.3390/ijms23031881

Pampusch, M. S., Abdelaal, H. M., Cartwright, E. K., Molden, J. S., Davey, B. C., Sauve, J. D., Sevcik, E. N., Rendahl, A. K., Rakasz, E. G., Connick, E., Berger, E. A. and Skinner, P. J. CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection. PLOS Pathogens. 2022; 18(2), e1009831. doi: 10.1371/journal.ppat.1009831

Aulicino, A., Antanaviciute, A., Frost, J., Sousa Geros, A., Mellado, E., Attar, M., Jagielowicz, M., Hublitz, P., Sinz, J., Preciado-Llanes, L., Napolitani, G., Bowden, R., Koohy, H., Drakesmith, H. and Simmons, A. Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion. Communications Biology. 2022; 5(1). doi: 10.1038/s42003-022-03038-z

Singh, D. K., Aladyeva, E., Das, S., Singh, B., Esaulova, E., Swain, A., Ahmed, M., Cole, J., Moodley, C., Mehra, S., Schlesinger, L. S., Artyomov, M. N., Khader, S. A. and Kaushal, D. Myeloid cell interferon responses correlate with clearance of SARS-CoV-2. Nature Communications. 2022; 13(1). doi: 10.1038/s41467-022-28315-7

Kuret, T., Sodin-Šemrl, S., Leskošek, B. and Ferk, P. Single Cell RNA Sequencing in Autoimmune Inflammatory Rheumatic Diseases: Current Applications, Challenges and a Step Toward Precision Medicine. Frontiers In Medicine. 2022; 8.22804. doi: 10.3389/fmed.2021.822804

Won, T., Wood, M. K., Hughes, D. M., Talor, M. V., Ma, Z., Schneider, J., Skinner, J. T., Asady, B., Goerlich, E., Halushka, M. K., Hays, A. G., Kim, D., Parikh, C. R., Rosenberg, A. Z., Coppens, I., Johns, R. A., Gilotra, N. A., Hooper, J. E., Pekosz, A. and Čiháková, D. Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs. Ebiomedicine. 2022; 75, 103812. doi: 10.1016/j.ebiom.2022.103812

Wong, D. P., Roy, N. K., Zhang, K., Anukanth, A., Asthana, A., Shirkey-Son, N. J., Dunmire, S., Jones, B. J., Lahr, W. S., Webber, B. R., Moriarity, B. S., Caimi, P. and Parameswaran, R. A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers. Nature Communications. 2022; 13(1). doi: 10.1038/s41467-021-27853-w

Heitzeneder, S., Bosse, K. R., Zhu, Z., Zhelev, D., Majzner, R. G., Radosevich, M. T., Dhingra, S., Sotillo, E., Buongervino, S., Pascual-Pasto, G., Garrigan, E., Xu, P., Huang, J., Salzer, B., Delaidelli, A., Raman, S., Cui, H., Martinez, B., Bornheimer, S. J., Sahaf, B., Alag, A., Fetahu, I. S., Hasselblatt, M., Parker, K. R., Anbunathan, H., Hwang, J., Huang, M., Sakamoto, K., Lacayo, N. J., Klysz, D. D., Theruvath, J., Vilches-Moure, J. G., Satpathy, A. T., Chang, H. Y., Lehner, M., Taschner-Mandl, S., Julien, J., Sorensen, P. H., Dimitrov, D. S., Maris, J. M. and Mackall, C. L. GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity. Cancer Cell. 2021; 40(1), pp. 53-69.e9. doi: 10.1016/j.ccell.2021.12.005

Aldrin-Kirk, P., Åkerblom, M., Cardoso, T., Nolbrant, S., Adler, A. F., Liu, X., Heuer, A., Davidsson, M., Parmar, M. and Björklund, T. A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants. Stem Cell Reports. 2021; 17, pp. 1-14. doi: 10.1016/j.stemcr.2021.11.014

Rajasree Menon. Sample GSM5194453. Gene Expression Omnibus. 2021.

Paul-Joseph Aspuria, Sandro Vivona, Michele Bauer, Marie Semana, Navneet Ratti, Scott McCauley, Romina Riener, Rene de Waal Malefyt, Deepti Rokkam, Jan Emmerich, Rob A. Kastelein, Patrick J. Lupardus and Martin Oft. An orthogonal IL-2 and IL-2Rβ system drives persistence and activation of CAR T cells and clearance of bulky lymphoma. SCIENCE TRANSLATIONAL MEDICINE. 2021; 13(625). doi: 10.1126/scitranslmed.abg7565

Roukens, A. H. E., Pothast, C. R., König, M., Huisman, W., Dalebout, T., Tak, T., Azimi, S., Kruize, Y., Hagedoorn, R. S., Zlei, M., Staal, F. J. T., de Bie, F. J., van Dongen, J. J. M., Arbous, S. M., Zhang, J. L. H., Verheij, M., Prins, C., van der Does, A. M., Hiemstra, P. S., de Vries, J. J. C., Janse, J. J., Roestenberg, M., Myeni, S. K., Kikkert, M., Yazdanbakhsh, M., Heemskerk, M. H. M., Smits, H. H., Jochems, S. P., Arbous, M. S., van den Berg, B. M., de Bruin-Versteeg, S., Cannegieter, S., Canté, K., Cobbaert, C. M., van der Does, A. M., van Dongen, J. J. M., Eikenboom, J., Feltkamp, M. C. W., Geluk, A., Goeman, J. J., Giera, M., Groenland, R. J., Hankemeier, T., Heemskerk, M. H. M., Hiemstra, P. S., Hokke, C. H., van der Holst, R., Janse, J. J., Jochems, S. P., Joosten, S. A., Kikkert, M., Flores, S. K., Lamont, L., Manniën, J., de Mooij, B., Ottenhoff, T. H. M., Pike-Overzet, K., Pongracz, T., del Prado, M. R., Rosinach, N. Q., Roestenberg, M., Roos, M., Roukens, A. H. E., van der Sluijs-Gelling, A. J., Smits, H. H., Snijder, E. J., Staal, F. J. T., Trouw, L. A., Tsonaka, R., Verhoeven, A., Visser, L. G., de Vries, J. J. C., van Westerloo, D. J., Wigbers, J., van der Wijk, H. J., van Wissen, R. C., Wuhrer, M., Yazdanbakhsh, M., Zlei, M., Oud, J. A., Baysan, M., Wigbers, J., van Heurn, L. J., ter Haar, S. B., Toppenberg, A. G. L., Heerdink, L., van IJlzinga Veenstra, A. A., Eikenboom, A. M., Wubbolts, J. M., Uzorka, J., Lijfering, W., Meier, R., de Jonge, I., de Boer, M. G. J., van der Bom, A. G., Dekkers, O. M. and Rosendaal, F. Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19. Nature Immunology. 2021; 23(1), 23-32. doi: 10.1038/s41590-021-01095-w

Menon, R., Otto, E. A., Berthier, C. C., Nair, V., Farkash, E. A., Hodgin, J. B., Yang, Y., Luo, J., Woodside, K. J., Zamani, H., Norman, S. P., Wiggins, R. C., Kretzler, M. and Naik, A. S. Glomerular endothelial cell-podocyte stresses and crosstalk in structurally normal kidney transplants. Kidney International. 2022. doi: 10.1016/j.kint.2021.11.031

Yang, N. J., Isensee, J., Neel, D. V., Quadros, A. U., Zhang, H. B., Lauzadis, J., Liu, S. M., Shiers, S., Belu, A., Palan, S., Marlin, S., Maignel, J., Kennedy-Curran, A., Tong, V. S., Moayeri, M., Röderer, P., Nitzsche, A., Lu, M., Pentelute, B. L., Brüstle, O., Tripathi, V., Foster, K. A., Price, T. J., Collier, R. J., Leppla, S. H., Puopolo, M., Bean, B. P., Cunha, T. M., Hucho, T. and Chiu, I. M. Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons. Nature Neuroscience. 2021. doi: 10.1038/s41593-021-00973-8

Eadon, M. T., Dagher, P. C. and El-Achkar, T. M. Cellular and molecular interrogation of kidney biopsy specimens. Current Opinion In Nephrology & Hypertension. 2021; 31(2), 160-167. doi: 10.1097/mnh.0000000000000770

Elsemary, M. T., Maritz, M. F., Smith, L. E., Warkiani, M., Bandara, V., Napoli, S., Barry, S. C., Coombs, J. T. and Thierry, B. Inertial Microfluidic Purification of CAR‐T‐Cell Products. Advanced Biology. 2021; 2101018. doi: 10.1002/adbi.202101018

Li, Y., Mateu, E., Díaz, I. Impact of Cryopreservation on Viability, Phenotype, and Functionality of Porcine PBMC. Frontiers In Immunology. 2021; 12. doi: 10.3389/fimmu.2021.765667

Horie, S., Gonzalez, H., Brady, J., Devaney, J., Scully, M., O’Toole, D. and Laffey, J. G. Fresh and Cryopreserved Human Umbilical-Cord-Derived Mesenchymal Stromal Cells Attenuate Injury and Enhance Resolution and Repair following Ventilation-Induced Lung Injury. International Journal Of Molecular Sciences. 2021; 22(23), 12842. doi: 10.3390/ijms222312842

Rob, L., Cibula, D., Knapp, P., Mallmann, P., Klat, J., Minar, L., Bartos, P., Chovanec, J., Valha, P., Pluta, M., Novotny, Z., Spacek, J., Melichar, B., Kieszko, D., Fucikova, J., Hrnciarova, T., Korolkiewicz, R. P., Hraska, M., Bartunkova, J. and Spisek, R. Safety and efficacy of dendritic cell-based immunotherapy DCVAC/OvCa added to first-line chemotherapy (carboplatin plus paclitaxel) for epithelial ovarian cancer: a phase 2, open-label, multicenter, randomized trial. Journal for ImmunoTherapy of Cancer. 2022; 10(1), p. e003190. doi: 10.1136/jitc-2021-003190

Barreiro, Luis B. Sample GSM5149358: HMN83562_NI. Gene Expression Omnibus. 2021.

Orr, B., Sutton, K., Christian, S., Nash, T., Niemann, H., Hansen, L. L., McGrew, M. J., Jensen, S. R. and Vervelde, L. Novel chicken two-dimensional intestinal model comprising all key epithelial cell types and a mesenchymal sub-layer. Veterinary Research. 2021; 52(1). doi: 10.1186/s13567-021-01010-z

Remley, V. A., Jin, J., Sarkar, S., Moses, L., Prochazkova, M., Cai, Y., Shao, L., Liu, H., Fuksenko, T., Jin, P., Stroncek, D. F. and Highfill, S. L. High efficiency closed-system gene transfer using automated spinoculation. Journal Of Translational Medicine. 2021; 19(1). doi: 10.1186/s12967-021-03126-4

Korchak, J. A., Delawary, M., Huang, P., Zhang, C., Suda, K. and Zubair, A. C. Endothelial nitric oxide synthase-engineered mesenchymal stromal cells induce anti-inflammation in experimental immune models. Cytotherapy. 2021. doi: 10.1016/j.jcyt.2021.10.001

Whitehead, A. J., Hocker, J. D., Ren, B. and Engler, A. J. Improved epicardial cardiac fibroblast generation from iPSCs. Journal Of Molecular And Cellular Cardiology. 2022; 164, 58-68. doi: 10.1016/j.yjmcc.2021.11.011

Zhang, C., Delawary, M., Huang, P., Korchak, J. A., Suda, K. and Zubair, A. C. IL-10 mRNA Engineered MSCs Demonstrate Enhanced Anti-Inflammation in an Acute GvHD Model. Cells. 2021; 10(11), 3101. doi: 10.3390/cells10113101

Seung Mi Yoo, Vivan W.C. Lau, Craig Aarts, Bojana Bojovic, Gregory Steinberg, Joanne A. Hammill, Anna Dvorkin-Gheva, Raja Ghosh & Jonathan L. Bramson. Manufacturing T cells in hollow fiber membrane bioreactors changes their programming and enhances their potency. OncoImmunology. 2021; 10:1, 1995168. doi: 10.1080/2162402X.2021.1995168

Armitage, L. H., Stimpson, S. E., Santostefano, K. E., Sui, L., Ogundare, S., Newby, B. N., Castro-Gutierrez, R., Huber, M. K., Taylor, J. P., Sharma, P., Radichev, I. A., Perry, D. J., Fredette, N. C., Savinov, A. Y., Wallet, M. A., Terada, N., Brusko, T. M., Russ, H. A., Chen, J., Egli, D. and Mathews, C. E. Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes. Frontiers In Endocrinology. 2021; 12. doi: 10.3389/fendo.2021.737276

Medrano-Trochez, C., Chatterjee, P., Pradhan, P., Stevens, H. Y., Ogle, M. E., Botchwey, E. A., Kurtzberg, J., Yeago, C., Gibson, G. and Roy, K. Single-cell RNA-seq of out-of-thaw mesenchymal stromal cells shows tissue-of-origin differences and inter-donor cell-cycle variations. Stem Cell Research & Therapy. 2021; 12(1). doi: 10.1186/s13287-021-02627-9

Dailey, Lisa A., McCullough, Shaun D. Culture and Differentiation of Primary Human Tracheobronchial Epithelial Cells Using STEMCELL Technologies Pneumacult Media. Research Square, 03 Nov 2021. doi: 10.21203/rs.3.pex-1674/v1

Fahmi, A., Brügger, M., Démoulins, T., Zumkehr, B., Oliveira Esteves, B.I., Bracher, L., Wotzkow, C., Blank, F., Thiel, V., Baud, D., Alves, M.P. SARS-CoV-2 can infect and propagate in human placenta explants. Cell Reports Medicine. 2021; 100456. doi: 10.1016/j.xcrm.2021.100456

Jung, D., Baek, Y. S., Lee, I. J., Kim, K. Y., Jang, H., Hwang, S., Jung, J., Moon, Y., Park, K., Choi, Y. and An, H. J. Ex vivo expanded allogeneic natural killer cells have potent cytolytic activity against cancer cells through different receptor-ligand interactions. Journal Of Experimental & Clinical Cancer Research. 2021; 40(1). doi: 10.1186/s13046-021-02089-0

Chen, H., Chen, Y., Yu, S., Lai, W., Shen, Y., Shen, P., Lin, S., Chang, C. and Lee, S. Infrapatellar fat pad-derived mesenchymal stromal cell product for treatment of knee osteoarthritis: a first-in-human study with evaluation of the potency marker. Cytotherapy. 2021; 24(1), pp. 72-85. doi: 10.1016/j.jcyt.2021.08.006

Friedrich, M., Pohin, M., Jackson, M. A., Korsunsky, I., Bullers, S. J., Rue-Albrecht, K., Christoforidou, Z., Sathananthan, D., Thomas, T., Ravindran, R., Tandon, R., Peres, R. S., Sharpe, H., Wei, K., Watts, G. F. M., Mann, E. H., Geremia, A., Attar, M., Barone, F., Brenner, M., Buckley, C. D., Coles, M., Frei, A. P., Lassen, K. G., Powrie, F. M., McCuaig, S., Thomas, L., Collantes, E., Uhlig, H. H., Sansom, S. N., Easton, A., Raychaudhuri, S., Travis, S. P. and Powrie, F. M. IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies. Nature Medicine. 2021. doi: 10.1038/s41591-021-01520-5

Prakadan, S. M., Alvarez-Breckenridge, C. A., Markson, S. C., Kim, A. E., Klein, R. H., Nayyar, N., Navia, A. W., Kuter, B. M., Kolb, K. E., Bihun, I., Mora, J. L., Bertalan, M. S., Shaw, B., White, M., Kaplan, A., Stocking, J. H., Wadsworth, M. H., Lee, E. Q., Chukwueke, U., Wang, N., Subramanian, M., Rotem, D., Cahill, D. P., Adalsteinsson, V. A., Miller, J. W., Sullivan, R. J., Carter, S. L., Brastianos, P. K. and Shalek, A. K. Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases. Nature Communications. 2021; 12(1). doi: 10.1038/s41467-021-25860-5

Gee, S., Chandiramani, M., Seow, J., Pollock, E., Modestini, C., Das, A., Tree, T., Doores, K. J., Tribe, R. M. and Gibbons, D. L. The legacy of maternal SARS-CoV-2 infection on the immunology of the neonate. Nature Immunology. 2021. doi: 10.1038/s41590-021-01049-2

Erol, O. D., Pervin, B., Seker, M. E. and Aerts-Kaya, F. Effects of storage media, supplements and cryopreservation methods on quality of stem cells. World Journal Of Stem Cells. 2021; 13(9), 1197-1214. doi: 10.4252/wjsc.v13.i9.1197

Richards, R. M., Zhao, F., Freitas, K. A., Parker, K. R., Xu, P., Fan, A., Sotillo, E., Daugaard, M., Oo, H. Z., Liu, J., Hong, W., Sorensen, P. H., Chang, H. Y., Satpathy, A. T., Majzner, R. G., Majeti, R. and Mackall, C. L. NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity. Blood Cancer Discovery. 2021; 2(6), 648-665. doi: 10.1158/2643-3230.bcd-20-0208

Palen, K., Zurko, J., Johnson, B. D., Hari, P. and Shah, N. N.  Manufacturing chimeric antigen receptor T cells from cryopreserved peripheral blood cells: time for a collect-and-freeze model?  Cytotherapy. 2021; 23(11), P985-990.  doi: 10.1016/j.jcyt.2021.07.015

Cho, H., Gonzales-Wartz, K. K., Huang, D., Yuan M., Peterson, M., Liang, J., Beutler, N., Torres, J. L., Cong, Y., Postnikova, E., Bangaru, S., Talana, C. A., Shi, W., Yang, E. S., Zhang, Y., Leung, K., Wang, L., Peng, L., Skinner, J., Li, S., Wu, N. C., Liu, H., Dacon, C., Moyer,T., Cohen, M., Zhao, M., Lee, F. E., Weinberg, R. S.,Douagi, I., Gross, R., Schmaljohn, C., Pegu, A., Mascola, J. R., Holbrook, M., Nemazee, D., Rogers, T. F.,Ward, A. B., Wilson, I. A., Crompton, P. D., Tan, J.  Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.  Sci. Transl. Med. 2021.  doi: 10.1126/scitranslmed.abj5413

Smith, D., Price, D. R. G., Burrells, A., Faber, M. N., Hildersley, K. A., Chintoan-Uta, C., Chapuis, A. F., Stevens, M., Stevenson, K., Burgess, S. T. G., Innes, E. A., Nisbet, A. J. and McNeilly, T. N.  The Development of Ovine Gastric and Intestinal Organoids for Studying Ruminant Host-Pathogen Interactions.  Frontiers In Cellular And Infection Microbiology. 2021; 11.  doi: 10.3389/fcimb.2021.733811

William McCoull, Scott Boyd, Martin R. Brown, Muireann Coen, Olga Collingwood, Nichola L. Davies, Ann Doherty, Gary Fairley, Kristin Goldberg, Elizabeth Hardaker, Guang He, Edward J. Hennessy, Philip Hopcroft, George Hodgson, Anne Jackson, Xiefeng Jiang, Ankur Karmokar, Anne-Laure Lainé, Nicola Lindsay, Yumeng Mao, Roshini Markandu, Lindsay McMurray, Neville McLean, Lorraine Mooney, Helen Musgrove, J. Willem M. Nissink, Alexander Pflug, Venkatesh Pilla Reddy, Philip B. Rawlins, Emma Rivers, Marianne Schimpl, Graham F. Smith, Sharon Tentarelli, Jon Travers, Robert I. Troup, Josephine Walton, Cheng Wang, Stephen Wilkinson, Beth Williamson, Jon Winter-Holt, Dejian Yang, Yuting Zheng, Qianxiu Zhu, and Paul D. Smith.  Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.  Journal Of Medicinal Chemistry. 2021; Article ASAP.  doi: 10.1021/acs.jmedch

Schaniel, C., Papa, L., Meseck, M. L., Kintali, M., Djedaini, M., Zangui, M., Iancu-Rubin, C. and Hoffman, R.  Evaluation of a clinical-grade, cryopreserved, ex vivo-expanded stem cell product from cryopreserved primary umbilical cord blood demonstrates multilineage hematopoietic engraftment in mouse xenografts.  Cytotherapy. 2021; 23(9), 841-851.  doi: 10.1016/j.jcyt.2021.04.001

Gilfanova, R., Auclair, K. M., Hui, A., Norris, P. J. and Muench, M. O. Reduced dimethyl sulfoxide concentrations successfully cryopreserve human hematopoietic stem cells with multi-lineage long-term engraftment ability in mice. Cytotherapy. 2021; 23(12), 1053-1059. doi: 10.1016/j.jcyt.2021.07.007

Paavola, K. J., Roda, J. M., Lin, V. Y., Chen, P., O’Hollaren, K. P., Ventura, R., Crawley, S. C., Li, B., Chen, H. H., Malmersjö, S., Sharkov, N. A., Horner, G., Guo, W., Kutach, A. K., Mondal, K., Zhang, Z., Lichtman, J. S., Song, C., Rivera, L. B., Liu, W., Luo, J., Wang, Y., Solloway, M. J., Allan, B. B., Kekatpure, A., Starck, S. R., Haldankar, R., Fan, B., Chu, C., Tang, J., Molgora, M., Colonna, M., Kaplan, D. D. and Hsu, J. The Fibronectin–ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells. Cancer Immunology Research. 2021; 9(11), 1283-1297. doi: 10.1158/2326-6066.cir-21-0240

van der Walle, C.F., Godbert, S., Saito, G., Azhari, Z.  Formulation Considerations for Autologous T Cell Drug Products.  Pharmaceutics 2021; 13, 1317.  doi: 10.3390/pharmaceutics13081317

Bluhmki, T., Traub, S., Müller, A., Bitzer, S., Schruf, E., Bammert, M., Leist, M., Gantner, F., Garnett, J. P. and Heilker, R.  Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96‑Transwell air–liquid interface model.  Scientific Reports. 2021; 11(1).  doi: 10.1038/s41598-021-96565-4

Nagarathinam Selvaraj, Chao-Kuei Wang, Brian Bowser, Trevor Broadt, Samir Shaban, Jenna Burns, Nirmala Saptharishi, Peter Pechan, Diane Golebiowski, Asaf Alimardanov, Nora Yang, George Mitra, and Ramarao Vepachedu.  Detailed Protocol for the Novel and Scalable Viral Vector Upstream Process for AAV Gene Therapy Manufacturing.  Human Gene Therapy. 2021; 32(15-16), 850-861.  doi: 10.1089/hum.2020.054

Dumas, P., Villacreces, A., Guitart, A. V., El-habhab, A., Massara, L., Mansier, O., Bidet, A., Martineau, D., Fernandez, S., Leguay, T., Pigneux, A., Vigon, I., Pasquet, J. and Desplat, V. Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3-ITD Acute Myeloid Leukemia.  Clinical Cancer Research. 2021; 27:6012-25. doi: 10.1158/1078-0432.ccr-20-3114

Dumas, P., Villacreces, A., Guitart, A. V., Ali, E. H., Massara, L., Mansier, O., Bidet, A., Martineau, D., Fernandez, S., Leguay, T., Pigneux, A., Vigon, I., Pasquet, J. and Desplat, V. Dual inhibition of FLT3 and AXL by gilteritinib overcomes hematopoietic niche-driven resistance mechanisms in FLT3-ITD acute myeloid leukemia.  Clinical Cancer Research. August 16 2021.  doi: 10.1158/1078-0432.ccr-20-3114

Tian E., Zhang M., and Shi Y. Direct Reprogramming of Fibroblasts to Astrocytes Using Small Molecules.  In: Ahlenius H. (eds) Neural Reprogramming. Methods in Molecular Biology. 2021; vol 2352, pp. 45-55. Humana, New York, NY.  doi: 10.1007/978-1-0716-1601-7_4

Quist E., Ahlenius H., and Canals I.  Transcription Factor Programming of Human Pluripotent Stem Cells to Functionally Mature Astrocytes for Monocultures and Cocultures with Neurons.  In: Ahlenius H. (eds) Neural Reprogramming. Methods in Molecular Biology. 2021; vol 2352, pp. 133-148. Humana, New York, NY.  doi: 10.1007/978-1-0716-1601-7_10

Deonaraine, K. K., Carlucci, P. M., Fava, A., Li, J., Wofsy, D., James, J. A., Putterman, C., Diamond, B., Davidson, A., Fine, D. M., Monroy-Trujillo, J., Atta, M. G., Haag, K., Rao, D. A., Apruzzese, W., Belmont, H. M., Izmirly, P. M., Wu, M., Connery, S., Payan-Schober, F., Furie, R. A., Berthier, C. C., Dall’Era, M., Cho, K., Kamen, D. L., Kalunian, K., Anolik, J., Ishimori, M., Weisman, M. H., Petri, M. A. and Buyon, J. P.  Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network.  Lupus Science & Medicine. 2021; 8(1), e000522.  doi: 10.1136/lupus-2021-000522

Keddache, S., Laheurte, C., Boullerot, L., Laurent, L., Dalphin, J., Adotevi, O. and Soumagne, T.  Inflammatory and immunological profile in COPD secondary to organic dust exposure.  Clinical Immunology. 2021; 108798.  doi: 10.1016/j.clim.2021.108798

Giacomelli, E., Sala, L., Oostwaard, D. W. and Bellin, M.  Cardiac microtissues from human pluripotent stem cells recapitulate the phenotype of long-QT syndrome.  Biochemical And Biophysical Research Communications. 2021; 572, 118-124.  doi: 10.1016/j.bbrc.2021.07.068

Lupo, K. B., Moon, J., Chambers, A. M. and Matosevic, S. Differentiation of natural killer cells from induced pluripotent stem cells under defined, serum- and feeder-free conditions. Cytotherapy. 2021; 23(10), 939-952. doi: 10.1016/j.jcyt.2021.05.001

Vitanza, N. A., Johnson, A. J., Wilson, A. L., Brown, C., Yokoyama, J. K., Künkele, A., Chang, C. A., Rawlings-Rhea, S., Huang, W., Seidel, K., Albert, C. M., Pinto, N., Gust, J., Finn, L. S., Ojemann, J. G., Wright, J., Orentas, R. J., Baldwin, M., Gardner, R. A., Jensen, M. C. and Park, J. R.  Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis.  Nature Medicine.  2021.  doi: 10.1038/s41591-021-01404-8

Gennert, D. G., Lynn, R. C., Granja, J. M., Weber, E. W., Mumbach, M. R., Zhao, Y., Duren, Z., Sotillo, E., Greenleaf, W. J., Wong, W. H., Satpathy, A. T., Mackall, C. L. and Chang, H. Y.  Dynamic chromatin regulatory landscape of human CAR T cell exhaustion.  Proceedings Of The National Academy Of Sciences. 2021; 118(30), e2104758118.  doi: 10.1073/pnas.2104758118

Reyes, M., Filbin, M. R., Bhattacharyya, R. P., Sonny, A., Mehta, A., Billman, K., Kays, K. R., Pinilla-Vera, M., Benson, M. E., Cosimi, L. A., Hung, D. T., Levy, B. D., Villani, A., Sade-Feldman, M., Baron, R. M., Goldberg, M. B., Blainey, P. C. and Hacohen, N.  Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro.  Science Translational Medicine. 2021; 13(598), eabe9599.  doi: 10.1126/scitranslmed.abe9599

Larson, A. and Chin, M. T.  A method for cryopreservation and single nucleus RNA-sequencing of normal adult human interventricular septum heart tissue reveals cellular diversity and function.  BMC Medical Genomics. 2021; 14(1).  doi: 10.1186/s12920-021-01011-z

Soni, M., Migliori, E., Assal, A., Chan, H. T., Ciubotariu, R., Pan, J. B., Cicero, K., Pereira, M., Mapara, M. Y. and Muranski, P. Development of T-cell immunity in a liver and hematopoietic stem cell transplant recipient following coronavirus disease 2019 infection. Cytotherapy. 2021; 23(11), 980-984. doi: 10.1016/j.jcyt.2021.05.005

Braudeau, C., Salabert‐Le Guen, N., Chevreuil, J., Rimbert, M., Martin, J. C. and Josien, R. An easy and reliable whole blood freezing method for flow cytometry immuno‐phenotyping and functional analyses. Cytometry Part B: Clinical Cytometry. 2021; 100(6), 652-665. doi: 10.1002/cyto.b.21994

Wang, Y., Mohseni, M., Grauel, A., Diez, J. E., Guan, W., Liang, S., Choi, J. E., Pu, M., Chen, D., Laszewski, T., Schwartz, S., Gu, J., Mansur, L., Burks, T., Brodeur, L., Velazquez, R., Kovats, S., Pant, B., Buruzula, G., Deng, E., Chen, J. T., Sari-Sarraf, F., Dornelas, C., Varadarajan, M., Yu, H., Liu, C., Lim, J., Hao, H., Jiang, X., Malamas, A., LaMarche, M. J., Geyer, F. C., McLaughlin, M., Costa, C., Wagner, J., Ruddy, D., Jayaraman, P., Kirkpatrick, N. D., Zhang, P., Iartchouk, O., Aardalen, K., Cremasco, V., Dranoff, G., Engelman, J. A., Silver, S., Wang, H., Hastings, W. D. and Goldoni, S.  SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms.  Scientific Reports. 2021; 11(1). doi: 10.1038/s41598-021-80999-x.  doi: 10.1038/s41598-021-80999-x

Kusena, J. W. T., Shariatzadeh, M., Studd, A. J., James, J. R., Thomas, R. J. and Wilson, S. L.  The importance of cell culture parameter standardization: an assessment of the robustness of the 2102Ep reference cell line.  Bioengineered. 2021; 12(1), 341-357.  doi: 10.1080/21655979.2020.1870074

Yang, F., Patton, K., Kasprzyk, T., Long, B., Gupta, S., Zoog, S. J., Tracy, K. and Vettermann, C.  Validation of an IFN-gamma ELISpot assay to measure cellular immune responses against viral antigens in non-human primates.  Gene Therapy. 2021.  doi: 10.1038/s41434-020-00214-w

Fattorelli, N., Martinez-Muriana, A., Wolfs, L., Geric, I., De Strooper, B. and Mancuso, R.  Stem-cell-derived human microglia transplanted into mouse brain to study human disease.  Nature Protocols. 2021.  doi: 10.1038/s41596-020-00447-4

Lanzoni, G., Linetsky, E., Correa, D., Messinger Cayetano, S., Alvarez, R. A., Kouroupis, D., Alvarez Gil, A., Poggioli, R., Ruiz, P., Marttos, A. C., Hirani, K., Bell, C. A., Kusack, H., Rafkin, L., Baidal, D., Pastewski, A., Gawri, K., Leñero, C., Mantero, A. M. A., Metalonis, S. W., Wang, X., Roque, L., Masters, B., Kenyon, N. S., Ginzburg, E., Xu, X., Tan, J., Caplan, A. I., Glassberg, M. K., Alejandro, R. and Ricordi, C.  Umbilical cord mesenchymal stem cells for COVID ‐19 acute respiratory distress syndrome: A double‐blind, phase 1/2a, randomized controlled trial.  STEM CELLS Translational Medicine. 2021.  doi: 10.1002/sctm.20-0472

Mazini, L., Ezzoubi, M. and Malka, G.  Overview of current adipose-derived stem cell (ADSCs) processing involved in therapeutic advancements: flow chart and regulation updates before and after COVID-19.  Stem Cell Research & Therapy. 2021; 12(1).  doi: 10.1186/s13287-020-02006-w

Barbeau, S., Desprat, R., Eymard, B., Martinat, C., Lemaitre, J. and Legay, C. Generation of a human induced pluripotent stem cell line (iPSC) from peripheral blood mononuclear cells of a patient with a myasthenic syndrome due to mutation in COLQ.  Stem Cell Research. 2020; 49, 102106.  doi: 10.1016/j.scr.2020.102106

Mogilenko, D. A., Shpynov, O., Andhey, P. S., Arthur, L., Swain, A., Esaulova, E., Brioschi, S., Shchukina, I., Kerndl, M., Bambouskova, M., Yao, Z., Laha, A., Zaitsev, K., Burdess, S., Gillfilan, S., Stewart, S. A., Colonna, M. and Artyomov, M. N.  Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging.  Immunity. 2020. doi: 10.1016/j.immuni.2020.11.005

Shim, J., Kim, K., Kim, K. G., Choi, U., Kyung, J. W., Sohn, S., Lim, S. H., Choi, H., Ahn, T., Choi, H. J., Shin, D. and Han, I.  Safety and efficacy of Wharton’s jelly‐derived mesenchymal stem cells with teriparatide for osteoporotic vertebral fractures: A phase I/IIa study.  STEM CELLS Translational Medicine. 2020.  doi: 10.1002/sctm.20-0308

Carbonneau, S., Sharma, S., Peng, L., Rajan, V., Hainzl, D., Henault, M., Yang, C., Hale, J., Shulok, J., Tallarico, J., Porter, J., Brogdon, J., Dranoff, G., Bradner, J. E., Hild, M. and Guimaraes, C. P.  An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity.  Cell Chemical Biology. 2020.  doi: 10.1016/j.chembiol.2020.11.012

Benitez, E. K., Lomova Kaufman, A., Cervantes, L., Clark, D. N., Ayoub, P. G., Senadheera, S., Osborne, K., Sanchez, J. M., Crisostomo, R. V., Wang, X., Reuven, N., Shaul, Y., Hollis, R. P., Romero, Z. and Kohn, D. B.  Global and Local Manipulation of DNA Repair Mechanisms to Alter Site-Specific Gene Editing Outcomes in Hematopoietic Stem Cells.  Frontiers In Genome Editing. 2020; 2:601541.  doi: 10.3389/fgeed.2020.601541

Roark, R. S., Li, H., Williams, W. B., Chug, H., Mason, R. D., Gorman, J., Wang, S., Lee, F., Rando, J., Bonsignori, M., Hwang, K., Saunders, K. O., Wiehe, K., Moody, M. A., Hraber, P. T., Wagh, K., Giorgi, E. E., Russell, R. M., Bibollet-Ruche, F., Liu, W., Connell, J., Smith, A. G., DeVoto, J., Murphy, A. I., Smith, J., Ding, W., Zhao, C., Chohan, N., Okumura, M., Rosario, C., Ding, Y., Lindemuth, E., Bauer, A. M., Bar, K. J., Ambrozak, D., Chao, C. W., Chuang, G., Geng, H., Lin, B. C., Louder, M. K., Nguyen, R., Zhang, B., Lewis, M. G., Raymond, D., Doria-Rose, N. A., Schramm, C. A., Douek, D. C., Roederer, M., Kepler, T. B., Kelsoe, G., Mascola, J. R., Kwong, P. D., Korber, B. T., Harrison, S. C., Haynes, B. F., Hahn, B. H. and Shaw, G. M.  Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth.  Science. 2020; 371(6525), eabd2638.  doi: 10.1126/science.abd2638

Herzig MC, Delavan CP, Jensen KJ, Cantu C, Montgomery RK, Christy BA, Cap AP, Bynum JA.  A streamlined proliferation assay using mixed lymphocytes for evaluation of human mesenchymal stem cell immunomodulation activity.  J Immunol Methods. 2020 Nov 16:112915.  doi: 10.1016/j.jim.2020.112915

Mirizio, E., Tabib, T., Wang, X., Chen, W., Liu, C., Lafyatis, R., Jacobe, H. and Torok, K. S.  Single-cell transcriptome conservation in a comparative analysis of fresh and cryopreserved human skin tissue: pilot in localized scleroderma.  Arthritis Research & Therapy. 2020; 22(1).  doi: 10.1186/s13075-020-02343-4

Li, Y., Bouza, M., Wu, C., Guo, H., Huang, D., Doron, G., Temenoff, J. S., Stecenko, A. A., Wang, Z. L. and Fernández, F. M.  Sub-nanoliter metabolomics via mass spectrometry to characterize volume-limited samples.  Nature Communications. 2020; 11(1).  doi: 10.1038/s41467-020-19444-y

Todd CJ Berard, Aby J Mathew.  Biopreservation and cold chain biologistics risk points in the cell and gene therapy workflow.  Cell & Gene Therapy Insights 2020; 6(08), 1363–1380.  doi: 10.18609/cgti.2020.150

Beh, S. T., Frisch, C., Brafman, D. A., Churko, J., Walker, J. E., Serrano, G. E., Sue, L. I., Reiman, E. M., Beach, T. G. and Lue, L.   Human Autopsy-Derived Scalp Fibroblast Biobanking for Age-Related Neurodegenerative Disease Research.  Cells. 2020; 9(11), 2383.  doi: 10.3390/cells9112383

Sade, M., Reyes, M. and Chloe, A.  MGH COVID-19 Effort Blood Processing Protocol for PBMC, Neutrophils and Plasma Isolation.  protocols.io. 2020.  doi: 10.17504/protocols.io.bjhnkj5e

Klara Valyi-Nagy, Fay Betsou, Alexandru Susma, and Tibor Valyi-Nagy.  Optimization of Viable Glioblastoma Cryopreservation for Establishment of Primary Tumor Cell Cultures.  BIOPRESERVATION AND BIOBANKING.  doi: 10.1089/bio.2020.0050

Nguyen, L. T., Trieu, T. T. H., Bui, H. T. H., Hoang, V. T., Nguyen, A. T. T., Trinh, N. T. H., Nguyen, K. T. and Hoang, D. M.  Allogeneic administration of human umbilical cord-derived mesenchymal stem/stromal cells for bronchopulmonary dysplasia: preliminary outcomes in four Vietnamese infants.  Journal Of Translational Medicine. 2020; 18, 398.  doi: 10.1186/s12967-020-02568-6

Block, M. S., Dietz, A. B., Gustafson, M. P., Kalli, K. R., Erskine, C. L., Youssef, B., Vijay, G. V., Allred, J. B., Pavelko, K. D., Strausbauch, M. A., Lin, Y., Grudem, M. E., Jatoi, A., Klampe, C. M., Wahner-Hendrickson, A. E., Weroha, S. J., Glaser, G. E., Kumar, A., Langstraat, C. L., Solseth, M. L., Deeds, M. C., Knutson, K. L. and Cannon, M. J.  Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients.  Nature Communications.  2020; 11(1).  doi: 10.1038/s41467-020-18962-z

Menon, R., Otto, E. A., Sealfon, R., Nair, V., Wong, A. K., Theesfeld, C. L., Chen, X., Wang, Y., Boppana, A. S., Luo, J., Yang, Y., Kasson, P. M., Schaub, J. A., Berthier, C. C., Eddy, S., Lienczewski, C. C., Godfrey, B., Dagenais, S. L., Sohaney, R., Hartman, J., Fermin, D., Subramanian, L., Looker, H. C., Harder, J. L., Mariani, L. H., Hodgin, J. B., Sexton, J. Z., Wobus, C. E., Naik, A. S., Nelson, R. G., Troyanskaya, O. G. and Kretzler, M.  SARS-CoV-2 receptor networks in diabetic and COVID-19 associated kidney disease.  Kidney International. 2020.  doi: 10.1016/j.kint.2020.09.015

Ha, C. W., Martin, A., Sepich-Poore, G. D., Shi, B., Wang, Y., Gouin, K., Humphrey, G., Sanders, K., Ratnayake, Y., Chan, K. S., Hendrick, G., Caldera, J., Arias, C., Moskowitz, J. E., Ho Sui, S. J., Yang, S., Underhill, D., Brady, M. J., Knott, S., Kaihara, K., Steinbaugh, M. J., Li, H., McGovern, D. P., Knight, R., Fleshner, P. and Devkota, S.  Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans.  Cell. 2020.  doi: 10.1016/j.cell.2020.09.009

Noh, J., Oh, S., Park, I. and Song, J.  Intracerebral Transplants of GMP-Grade Human Umbilical Cord-Derived Mesenchymal Stromal Cells Effectively Treat Subacute-Phase Ischemic Stroke in a Rodent Model.  Frontiers In Cellular Neuroscience. 2020; 14.  doi: 10.3389/fncel.2020.546659

Wang, X., Karki, U., Abeygunaratne, H., UnnoldCofre, C. and Xu, J.  Plant cell-secreted stem cell factor stimulates expansion and differentiation of hematopoietic stem cells.  Process Biochemistry. 2021; 100, 39-48.  doi: 10.1016/j.procbio.2020.09.029

Esser, L. K., Branchi, V., Leonardelli, S., Pelusi, N., Simon, A. G., Klümper, N., Ellinger, J., Hauser, S., Gonzalez-Carmona, M. A., Ritter, M., Kristiansen, G., Schorle, H., Hölzel, M. and Toma, M. I.  Cultivation of Clear Cell Renal Cell Carcinoma Patient-Derived Organoids in an Air-Liquid Interface System as a Tool for Studying Individualized Therapy.  Frontiers In Oncology. 2020; 10.  doi: 10.3389/fonc.2020.01775

Penkava, F., Velasco-Herrera, M. D. C., Young, M. D., Yager, N., Nwosu, L. N., Pratt, A. G., Lara, A. L., Guzzo, C., Maroof, A., Mamanova, L., Cole, S., Efremova, M., Simone, D., Filer, A., Brown, C. C., Croxford, A. L., Isaacs, J. D., Teichmann, S., Bowness, P., Behjati, S. and Hussein Al-Mossawi, M.  Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis.  Nature Communications. 2020; 11(1).  doi: 10.1038/s41467-020-18513-6

Nguyen, H. T. L. and Soragni, A.  Patient-Derived Tumor Organoid Rings for Histologic Characterization and High-Throughput Screening.  STAR Protocols. 2020; 1: 22.  doi: 10.1016/j.xpro.2020.100056

Chandra, J., Woo, W. P., Finlayson, N., Liu, H. Y., McGrath, M., Ladwa, R., Brauer, M., Xu, Y., Hanson, S., Panizza, B., Frazer, I. H. and Porceddu, S. V.  A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC).  Cancer Immunology, Immunotherapy (2020).  doi: 10.1007/s00262-020-02720-7

Zhou, X., Li, H., Li, F., Song, X., Liu, T., Ma, T., Guo, H., Wu, N. and Li, J.  Generation and characterization of two iPSC lines from human adipose tissue-derived stem cells of healthy donors.  Stem Cell Research. 2020; 48, 101973.  doi: 10.1016/j.scr.2020.101973

Johnstone, B. H., Miller, H. M., Beck, M. R., Gu, D., Thirumala, S., LaFontaine, M., Brandacher, G. and Woods, E. J.  Identification and characterization of a large source of primary mesenchymal stem cells tightly adhered to bone surfaces of human vertebral body marrow cavities.  Cytotherapy. 2020; 22(11), 617-628.  doi: 10.1016/j.jcyt.2020.07.003

Thirlwell, K. L., Colligan, D., Mountford, J. C., Samuel, K., Bailey, L., Cuesta-Gomez, N., Hewit, K. D., Kelly, C. J., West, C. C., McGowan, N. W., Casey, J. J., Graham, G. J., Turner, M. L., Forbes, S. and Campbell, J. D.  Pancreas-derived mesenchymal stromal cells share immune response-modulating and angiogenic potential with bone marrow mesenchymal stromal cells and can be grown to therapeutic scale under Good Manufacturing Practice conditions.  Cytotherapy. 2020; 22(12), 762-771.  doi: 10.1016/j.jcyt.2020.07.010

Di Giorgio, E., Wang, L., Xiong, Y., Akimova, T., Christensen, L. M., Han, R., Samanta, A., Trevisanut, M., Bhatti, T. R., Beier, U. H. and Hancock, W. W.  Mef2d sustains activation of effector Foxp3+ Tregs during transplant survival and anticancer immunity.  Journal Of Clinical Investigation.  2020.  doi: 10.1172/jci135486

Chen, X., Chen, Y., Lin, W., Chien, C., Chen, C., Wen, Y., Hsiao, T. and Chuang, H.  Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells on the Acute Cigarette Smoke-Induced Pulmonary Inflammation Model.  Frontiers In Physiology. 2020; 11.  doi: 10.3389/fphys.2020.00962

Khalsa, J. K., Cheng, N., Keegan, J., Chaudry, A., Driver, J., Bi, W. L., Lederer, J. and Shah, K.  Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types.  Nature Communications. 2020; 11(1).  doi: 10.1038/s41467-020-17704-5

Makkar, R. R., Kereiakes, D. J., Aguirre, F., Kowalchuk, G., Chakravarty, T., Malliaras, K., Francis, G. S., Povsic, T. J., Schatz, R., Traverse, J. H., Pogoda, J. M., Smith, R. R., Marbán, L., Ascheim, D. D., Ostovaneh, M. R., Lima, J. A. C., DeMaria, A., Marbán, E. and Henry, T. D.  Intracoronary ALLogeneic heart STem cells to Achieve myocardial Regeneration (ALLSTAR): a randomized, placebo-controlled, double-blinded trial.  European Heart Journal.  2020; 41(36), 3451-3458.  doi: 10.1093/eurheartj/ehaa541

Corridoni, D., Antanaviciute, A., Gupta, T., Fawkner-Corbett, D., Aulicino, A., Jagielowicz, M., Parikh, K., Repapi, E., Taylor, S., Ishikawa, D., Hatano, R., Yamada, T., Xin, W., Slawinski, H., Bowden, R., Napolitani, G., Brain, O., Morimoto, C., Koohy, H. and Simmons, A.  Single-cell atlas of colonic CD8+ T cells in ulcerative colitis.  Nature Medicine.  2020; 26(9), 1480-1490.  doi: 10.1038/s41591-020-1003-4

Bluhmki, T., Bitzer, S., Gindele, J. A., Schruf, E., Kiechle, T., Webster, M., Schymeinsky, J., Ries, R., Gantner, F., Bischoff, D., Garnett, J. and Heilker, R.  Development of a miniaturized 96-Transwell air–liquid interface human small airway epithelial model.   Scientific Reports. 2020; 10(1).  doi: 10.1038/s41598-020-69948-2

Jayawardena, A., Liu, T., Pereira, B., Wang, Y., Baker, L., Leary, R., Mirambeaux, M., Zablah, E., Sabatos-Peyton, C. and Hartnick, C.  Immune Signature Variation in Twins With Clinically Different Recurrent Respiratory Papillomatosis.  Laryngoscope. 2020; 00: 1-4.  doi: 10.1002/lary.28930

Maeda, T., Kitamura, S., Nishihara, H. and Yanagi, T.  Extramammary Paget’s disease patient-derived xenografts harboring ERBB2 S310F mutation show sensitivity to HER2-targeted therapies.  Oncogene. 2020.  doi: 10.1038/s41388-020-01404-x

Skiles, M. L., Marzan, A. J., Brown, K. S. and Shamonki, J. M.  Comparison of umbilical cord tissue-derived mesenchymal stromal cells isolated from cryopreserved material and extracted by explantation and digestion methods utilizing a split manufacturing model.  Cytotherapy.  2020; 22:10, p581-591.  doi: 10.1016/j.jcyt.2020.06.002

Su, T., Ying, Z., Lu, X., He, T., Song, Y., Wang, X., Ping, L., Xie, Y., Tu, M., Liu, G., Qi, F., Ding, Y., Jing, H. and Zhu, J.  The clinical outcomes of fresh versus cryopreserved CD19-directed chimeric antigen receptor T cells in non-Hodgkin lymphoma patients.  Cryobiology.  2020; 96, 106-113.  doi: 10.1016/j.cryobiol.2020.07.009

Lee, H., Kim, H., Seo, J., Choi, K., Lee, Y., Park, K., Kim, S., Mobasheri, A. and Choi, H. TissueGene-C promotes an anti-inflammatory micro-environment in a rat monoiodoacetate model of osteoarthritis via polarization of M2 macrophages leading to pain relief and structural improvement. Inflammopharmacology. 2020; 28(5), 1237-1252. doi: 10.1007/s10787-020-00738-y

Filippo Buono, M., von Boehmer, L., Strang, J., P. Hoerstrup, S., Y. Emmert, M. and Nugraha, B.  Human Cardiac Organoids for Modeling Genetic Cardiomyopathy.  Cells. 2020; 9(7), 1733.  doi: 10.3390/cells9071733

Jones, M., Nankervis, B., Roballo, K. S., Pham, H., Bushman, J., and Coeshott, C.   A Comparison of Automated Perfusion- and Manual Diffusion-Based Human Regulatory T Cell Expansion and Functionality Using a Soluble Activator Complex.  Cell Transplantation. 2020; 29: 1-15. doi: 10.1177/0963689720923578

Ogle, M. E., Doron, G., Levy, M. J. and Temenoff, J. S.  Hydrogel Culture Surface Stiffness Modulates Mesenchymal Stromal Cell Secretome and Alters Senescence.  Tissue Engineering Part A.  doi: 10.1089/ten.tea.2020.0030

Nelson, M. H., Knochelmann, H. M., Bailey, S. R., Huff, L. W., Bowers, J. S., Majchrzak-Kuligowska, K., Wyatt, M. M., Rubinstein, M. P., Mehrotra, S., Nishimura, M. I., Armeson, K. E., Giresi, P. G., Zilliox, M. J., Broxmeyer, H. E. and Paulos, C. M.  Identification of human CD4+ T cell populations with distinct antitumor activity.  Science Advances. 2020; 6(27), eaba7443.  doi: 10.1126/sciadv.aba7443

Nelson, J., Sorensen, E. W., Mintri, S., Rabideau, A. E., Zheng, W., Besin, G., Khatwani, N., Su, S. V., Miracco, E. J., Issa, W. J., Hoge, S., Stanton, M. G. and Joyal, J. L.  Impact of mRNA chemistry and manufacturing process on innate immune activation.  Science Advances. 2020; 6(26), eaaz6893.  doi: 10.1126/sciadv.aaz6893

He, A., Powell, S., Kyle, M., Rose, M., Masmila, E., Estrada, V., Sicklick, J. K., Molinolo, A. and Kaushal, S.  Cryopreservation of Viable Human Tissues: Renewable Resource for Viable Tissue, Cell Lines, and Organoid Development.  Biopreservation And Biobanking. 2020; 18(3), 222-227.  doi: 10.1089/bio.2019.0062

Kleinveld, D. J., Sloos, P. H., Noorman, F., Maas, M. A. W., Kers, J., Rijnhout, T. W., Zoodsma, M., Hoencamp, R., Hollmann, M. W. and Juffermans, N. P.  The use of cryopreserved platelets in a trauma‐induced hemorrhage model.  Transfusion. 2020; 60(9), 2079-2089.  doi: 10.1111/trf.15937

Trzupek, D., Dunstan, M., Cutler, A. J., Lee, M., Godfrey, L., Jarvis, L., Rainbow, D. B., Aschenbrenner, D., Jones, J. L., Uhlig, H. H., Wicker, L. S., Todd, J. A. and Ferreira, R. C.  Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis.  Genome Medicine. 2020; 12(1).  doi: 10.1186/s13073-020-00756-z

Sakabe, S., Hartnett, J. N., Ngo, N., Goba, A., Momoh, M., Sandi, J. D., Kanneh, L., Cubitt, B., Garcia, S. D., Ware, B. C., Kotliar, D., Robles-Sikisaka, R., Gangavarapu, K., Branco, L. M., Eromon, P., Odia, I., Ogbaini-Emovon, E., Folarin, O., Okogbenin, S., Okokhere, P. O., Happi, C., Sabeti, P. C., Andersen, K. G., Garry, R. F., de la Torre, J. C., Grant, D. S., Schieffelin, J. S., Oldstone, M. B. A. and Sullivan, B. M.  Identification of Common CD8+ T Cell Epitopes from Lassa Fever Survivors in Nigeria and Sierra Leone.  Journal Of Virology. 2020; 94(12).  doi: 10.1128/jvi.00153-20

Toombs, J., Panther, L., Ornelas, L., Liu, C., Gomez, E., Martín-Ibáñez, R., Cox, S. R., Ritchie, S. J., Harris, S. E., Taylor, A., Redmond, P., Russ, T. C., Murphy, L., Cooper, J. D., Burr, K., Selvaraj, B. T., Browne, C., Svendsen, C. N., Cowley, S. A., Deary, I. J., Chandran, S., Spires-Jones, T., Sareen, D.  Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936.  Stem Cell Research. 2020; 46, 101851.  doi: 10.1101/2020.02.05.935213

Singh, S., Chakravarty, T., Chen, P., Akhmerov, A., Falk, J., Friedman, O., Zaman, T., Ebinger, J. E., Gheorghiu, M., Marbán, L., Marbán, E. and Makkar, R. R.  Allogeneic cardiosphere-derived cells (CAP-1002) in critically ill COVID-19 patients: compassionate-use case series.  Basic Research In Cardiology. 2020; 115(4).  doi: 10.1007/s00395-020-0795-1

Algazi, A. P., Twitty, C. G., Tsai, K. K., Le, M., Pierce, R., Browning, E., Hermiz, R., Canton, D. A., Bannavong, D., Oglesby, A., Francisco, M., Fong, L., Pittet, M. J., Arlauckas, S. P., Garris, C., Levine, L. P., Bifulco, C., Ballesteros-Merino, C., Bhatia, S., Gargosky, S., Andtbacka, R. H., Fox, B. A., Rosenblum, M. D. and Daud, A. I.  Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma.  Clinical Cancer Research.  2020; 26(12), 2827-2837.  doi: 10.1158/1078-0432.ccr-19-2217

Konala, V. B. R., Nandakumar, S., Battu, R. and Pal, R.  Derivation of three induced pluripotent stem cell lines under feeder-free culture conditions from peripheral blood mononuclear cells (PBMC) of Indian patients suffering from inherited retinal diseases carrying different mutations.  Stem Cell Research. 2020; 45, 101757.  doi: 10.1016/j.scr.2020.101757

Tariq, M., Liu, H., Ibañez, D. P., Li, Y., Chen, S., Jiang, M., Fan, W., Zhao, P., Luo, Z., Wang, D. and Kanwal, S.  Generation of three induced pluripotent stem cell lines from a Parkinson’s disease patient with mutant PARKIN (p. C253Y).  Stem Cell Research. 2020; 45, 101822.  doi: 10.1016/j.scr.2020.101822

Lanzoni G., Linetsky E., Correa D., Alvarez R. A., Marttos A., Hirani K., Messinger Cayetano S., Castro J. G., Paidas M. J., Efantis Potter J., Xu X., Glassberg M., Tan J., Patel A. N., Goldstein G., Kenyon N. S., Baidal D., Alejandro R., Vianna R., Ruiz P., Caplan A. I., and Ricordi C.  Umbilical cord-derived mesenchymal stem cells for COVID-19 patients with acute respiratory distress syndrome (ARDS).  CellR4 2020; 8: e2839.  doi: 10.32113/cellr4_20204_2839

Awan, M., Buriak, I., Fleck, R., Fuller, B., Goltsev, A., Kerby, J., Lowdell, M., Mericka, P., Petrenko, A., Petrenko, Y., Rogulska, O., Stolzing, A., and Stacey, G. N.  Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?  Regenerative Medicine 2020 15:3, 1463-1491.  doi: 10.2217/rme-2019-0145

Santeramo, I., Bagnati, M., Harvey, E.J., Hassan, E., Surmacz-Cordle, B., Marshall, D., Di Cerbo, V.  Vector copy distribution at a single cell level enhances analytical characterisation of gene-modified cell therapies.  Molecular Therapy – Methods & Clinical Development. 2020; 17, 944-956.  doi: 10.1016/j.omtm.2020.04.016.

Wei, K., Korsunsky, I., Marshall, J. L., Gao, A., Watts, G. F. M., Major, T., Croft, A. P., Watts, J., Blazar, P. E., Lange, J. K., Thornhill, T. S., Filer, A., Raza, K., Donlin, L. T., Siebel, C. W., Buckley, C. D., Raychaudhuri, S. and Brenner, M. B.  Notch signalling drives synovial fibroblast identity and arthritis pathology.  Nature. 2020.  doi: 10.1038/s41586-020-2222-z

Motwani, K., Peters, L. D., Vliegen, W. H., El-sayed, A. G., Seay, H. R., Lopez, M. C., Baker, H. V., Posgai, A. L., Brusko, M. A., Perry, D. J., Bacher, R., Larkin, J., Haller, M. J. and Brusko, T. M.  Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood.  Front. Immunol. 2020; 11:611.  doi: 10.3389/fimmu.2020.00611

Agresta, L., Lehn, M., Lampe, K., Cantrell, R., Hennies, C., Szabo, S., Wise-Draper, T., Conforti, L., Hoebe, K. and Janssen, E. M.  CD244 represents a new therapeutic target in head and neck squamous cell carcinoma.  Journal For Immunotherapy Of Cancer.  2020; 8(1), e000245.  doi: 10.1136/jitc-2019-000245

Buchheit, K. M., Dwyer, D. F., Ordovas-Montanes, J., Katz, H. R., Lewis, E., Vukovic, M., Lai, J., Bankova, L. G., Bhattacharyya, N., Shalek, A. K., Barrett, N. A., Boyce, J. A. and Laidlaw, T. M.  IL-5Rα marks nasal polyp IgG4- and IgE-expressing cells in aspirin-exacerbated respiratory disease.  Journal Of Allergy And Clinical Immunology. 2020; 145(6), 1574-1584.  doi: 10.1016/j.jaci.2020.02.035

Spindler, M. J., Nelson, A. L., Wagner, E. K., Oppermans, N., Bridgeman, J. S., Heather, J. M., Adler, A. S., Asensio, M. A., Edgar, R. C., Lim, Y. W., Meyer, E. H., Hawkins, R. E., Cobbold, M. and Johnson, D. S.  Massively parallel interrogation and mining of natively paired human TCRαβ repertoires.  Nature Biotechnology (2020).  doi: 10.1038/s41587-020-0438-y

Hanidziar, D., Nakahori, Y., Cahill, L. A., Gallo, D., Keegan, J. W., Nguyen, J. P., Otterbein, L. E., Lederer, J. A. and Robson, S. C..  Characterization of pulmonary immune responses to hyperoxia by high-dimensional mass cytometry analyses.  Scientific Reports. 2020; 10(1), 4677.  doi: 10.1038/s41598-020-61489-y

Hanna, S. J., Powell, W. E., Long, A. E., Robinson, E. J. S., Davies, J., Megson, C., Howell, A., Jones, T. J., Ladell, K., Price, D. A., Dayan, C. M., Williams, A. J. K., Gillespie, K. M. and Wong, F. S.  Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype.  Diabetologia (2020).  doi: 10.1007/s00125-020-05114-7

Hobbs, J. M., Vazquez, A. R., Remijan, N. D., Trotter, R. E., McMillan, T. V., Freedman, K. E., Wei, Y., Woelfel, K. A., Arnold, O. R., Wolfe, L. M., Johnson, S. A. and Weir, T. L.  Evaluation of pharmacokinetics and acute anti‐inflammatory potential of two oral cannabidiol preparations in healthy adults.  Phytotherapy Research. 2020; 34(7), 1696-1703.  doi: 10.1002/ptr.6651

Menon, R., Otto, E. A., Hoover, P. J., Eddy, S., Mariani, L. H., Godfrey, B., Berthier, C. C., Eichinger, F., Subramanian, L., Harder, J. L., Ju, W., Nair, V., Larkina, M., Naik, A. S., Luo, J., jain, S., Sealfon, R., Troyanskaya, O. G., Hacohen, N., Hodgin, J. B. and Kretzler, M.  Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker.  JCI Insight. 2020; 5(6):e133267.  doi:10.1172/jci.insight.133267

Coppin, L. C. F., Smets, F., Ambroise, J., Sokal, E. E. M., Stéphenne, X.  Infusion-related thrombogenesis by liver-derived mesenchymal stem cells controlled by anticoagulant drugs in 11 patients with liver-based metabolic disorders.  Stem Cell Research & Therapy. 2020; 11(1).  doi: 10.1186/s13287-020-1572-7

Horie, S., Gaynard, S., Murphy, M., Barry, F., Scully, M., O’Toole, D. and Laffey, J. G.  Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism.  Intensive Care Medicine Experimental. 2020; 8(1).  doi: 10.1186/s40635-020-0295-5

Kohn, D. B., Booth, C., Kang, E. M., Pai, S., Shaw, K. L., Santilli, G., Armant, M., Buckland, K. F., Choi, U., De Ravin, S. S., Dorsey, M. J., Kuo, C. Y., Leon-Rico, D., Rivat, C., Izotova, N., Gilmour, K., Snell, K., Dip, J. X., Darwish, J., Morris, E. C., Terrazas, D., Wang, L. D., Bauser, C. A., Paprotka, T., Kuhns, D. B., Gregg, J., Raymond, H. E., Everett, J. K., Honnet, G., Biasco, L., Newburger, P. E., Bushman, F. D., Grez, M., Gaspar, H. B., Williams, D. A., Malech, H. L., Galy, A., Thrasher, A. J.  Lentiviral gene therapy for X-linked chronic granulomatous disease.  Nature Medicine. 2020; 26(2), 200-206.  doi: 10.1038/s41591-019-0735-5

Brudno, J. N., Lam, N., Vanasse, D., Shen, Y., Rose, J. J., Rossi, J., Xue, A., Bot, A., Scholler, N., Mikkilineni, L., Roschewski, M., Dean, R., Cachau, R., Youkharibache, P., Patel, R., Hansen, B., Stroncek, D. F., Rosenberg, S. A., Gress, R. E., Kochenderfer, J. N.  Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma.  Nature Medicine.  2020; 26(2), 270-280.  doi: 10.1038/s41591-019-0737-3

Lam, N., Trinklein, N., Buelow, B., Patterson, G., Ojha, N., Kochenderfer, J.  Anti-BCMA chimeric antigen receptors with fully human heavy-chain-only antigen recognition domains.  Nature Communications. 2020; 11(1).  doi: 10.1038/s41467-019-14119-9

Forbes, S., Bond, A. R., Thirlwell, K. L., Burgoyne, P., Samuel, K., Noble, J., Borthwick, G., Colligan, D., McGowan, N. W. A., Lewis, P. S., Fraser, A. R., Mountford, J. C., Carter, R. N., Morton, N. M., Turner, M. L., Graham, G. J., Campbell, J. D. M.  Human umbilical cord perivascular cells improve human pancreatic islet transplant function by increasing vascularization.  Science Translational Medicine. 2020; 12(526), eaan5907.  doi: 10.1126/scitranslmed.aan5907

Pomeroy, E. J., Hunzeker, J. T., Kluesner, M. G., Lahr, W. S., Smeester, B. A., Crosby, M. R., Lonetree, C., Yamamoto, K., Bendzick, L., Miller, J. S., Geller, M. A., Walcheck, B., Felices, M., Webber, B. R., Starr, T. K., Moriarity, B. S.  A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy.  Molecular Therapy. 2020; 28(1), 52-63.  doi:10.1016/j.ymthe.2019.10.009

Shafa, M., Walsh, T., Panchalingam, K. M., Richardson, T., Menendez, L., Tian, X., Suresh Babu, S., Dadgar, S., Beller, J., Yang, F., Baghbaderani, B. A.  Long-Term Stability and Differentiation Potential of Cryopreserved cGMP-Compliant Human Induced Pluripotent Stem Cells.  International Journal Of Molecular Sciences. 2020; 21(1), 108.  doi: 10.3390/ijms21010108

Lynn, R. C., Weber, E. W., Sotillo, E., Gennert, D., Xu, P., Good, Z., Anbunathan, H., Lattin, J., Jones, R., Tieu, V., Nagaraja, S., Granja, J., de Bourcy, C. F. A., Majzner, R., Satpathy, A. T., Quake, S. R., Monje, M., Chang, H. Y. and Mackall, C. L.  c-Jun overexpression in CAR T cells induces exhaustion resistance.  Nature. 2019; 576(7786), 293-300.  doi: 10.1038/s41586-019-1805-z

MacDonald, K. N., Ivison, S., Hippen, K. L., Hoeppli, R. E., Hall, M., Zheng, G., Dijke, I. E., Aklabi, M. A., Freed, D. H., Rebeyka, I., Gandhi, S., West, L. J., Piret, J. M., Blazar, B. R., Levings, M. K.  Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol.  Cytotherapy. 2019; 21(12), 1216-1233.  doi: 10.1016/j.jcyt.2019.10.011

Erkes, D. A., Cai, W., Sanchez, I. M., Purwin, T. J., Rogers, C., Field, C. O., Berger, A. C., Hartsough, E. J., Rodeck, U., Alnemri, E. S. and Aplin, A. E.  Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis. Cancer Discovery. 2019; 10(2), 254-269.  doi: 10.1158/2159-8290.cd-19-0672

Mata, M. F., Hernandez, D., Rologi, E., Grandolfo, D., Hassan, E., Hua, P., Kallmeier, R., Hirani, S., Heuts, F., Tittrea, V., Choo, Y., Baradez, M., Watt, S. M., Tarunina, M.  A modified CD34+ hematopoietic stem and progenitor cell isolation strategy from cryopreserved human umbilical cord blood.  Transfusion. 2019; 59(12), 3560-3569.  doi: 10.1111/trf.15597

Webber, B. R., Lonetree, C., Kluesner, M. G., Johnson, M. J., Pomeroy, E. J., Diers, M. D., Lahr, W. S., Draper, G., Slipek, N. J., Lovendahl, K. N., McElroy, A., Gordon, W. R., Osborn, M. J., Moriarity, B. S.  Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors.  Nat Commun. 2019; 10, 5222.  doi:10.1038/s41467-019-13007-6

Fedorova, L., Mudry, P., Pilatova, K., Selingerova, I., Merhautova, J., Rehak, Z., Valik, D., Hlavackova, E., Cerna, D., Faberova, L., Mazanek, P., Pavelka, Z., Demlova, R., Sterba, J., Zdrazilova-Dubska, L.  Assessment of Immune Response Following Dendritic Cell-Based Immunotherapy in Pediatric Patients With Relapsing Sarcoma.  Frontiers in Oncology. 2019; 9.  doi:10.3389/fonc.2019.01169

Abazari, A.  Process development considerations for cryopreservation of cellular therapies.  Cell & Gene Therapy Insights. 2019; 5(9), 1151–1167.  doi: 10.18609/cgti.2019.122

Patel, A., Clementelli, C. M., Jarocha, D., Mosoyan, G., Else, C., Kintali, M., Fong, H., Tong, J., Gordon, R., Gillespie, V., Keyzner, A., Poncz, M., Hoffman, R., Iancu‐Rubin, C.  Pre‐clinical development of a cryopreservable megakaryocytic cell product capable of sustained platelet production in mice.  Transfusion. 2019; 59(12), 3698-3713.  doi: 10.1111/trf.15546

Bahsoun, S., Coopman, K., Akam, E. C..  The impact of cryopreservation on bone marrow-derived mesenchymal stem cells: a systematic review.  Journal Of Translational Medicine. 2019; 17(1).  doi: 10.1186/s12967-019-02136-7

Guadix, J. A., López-Beas, J., Clares, B., Soriano-Ruiz, J. L., Zugaza, J. L., Gálvez-Martín, P.  Principal Criteria for Evaluating the Quality, Safety and Efficacy of hMSC-Based Products in Clinical Practice: Current Approaches and Challenges.  Pharmaceutics. 2019; 11(11), 552.  doi:10.3390/pharmaceutics11110552

Powers, R. K., Culp-Hill, R., Ludwig, M. P., Smith, K. P., Waugh, K. A., Minter, R., Tuttle, K. D., Lewis, H. C., Rachubinski, A. L., Granrath, R. E., Carmona-Iragui, M., Wilkerson, R. B., Kahn, D. E., Joshi, M., Lleó, A., Blesa, R., Fortea, J., D’Alessandro, A., Costello, J. C., Sullivan, K. D., Espinosa, J. M.  Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.  Nature Communications. 2019; 10(1).  doi:10.1038/s41467-019-12739-9

Curran, K. J., Margossian, S., Kernan, N. A., Silverman, L. B., Williams, D. A., Shukla, N. N., Kobos, R., Forlenza, C., Steinherz, P., Prockop, S., Boulad, F., Spitzer, B., Cancio, M. I., Boelens, J. J., Kung, A. L., Szenes, V. Z., Park, J., Sauter, C. S., Heller, G., Wang, X., Senechal, B., O’Reilly, R. J., Riviere, I., Sadelain, M., Brentjens, R. J.  Toxicity and Response following CD19-specific CAR T cells in pediatric/young adult relapsed/refractory B-ALL.  Blood. 2019; 2019001641.  doi:10.1182/blood.2019001641

Abdul, M. M., Ibañez, D. P., Zhao, P., Liu, H., Zhong, X., Li, Y., Zhang, M., Li, W., Li, Y., Ward, C., Chen, S., Wang, D., Qin, B., Esteban, M. A., Wang, X., Fan, W., Luo, Z.  Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson’s disease patient with mutant PINK1 (p. I368N).  Stem Cell Research. December 2019; 41, 101607.  doi:10.1016/j.scr.2019.101607

Aron Badin, R., Bugi, A., Williams, S., Vadori, M., Michael, M., Jan, C., Nassi, A., Lecourtois, S., Blancher, A., Cozzi, E., Hantraye, P., Perrier, A. L.  MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates.  Nature Communications. 2019; 10(1).  doi:10.1038/s41467-019-12324-0

Gooch, A., Zhang, P., Hu, Z., Loy Son, N., Avila, N., Fischer, J., Roberts, G., Sellon, R., Westenfelder, C.  Interim report on the effective intraperitoneal therapy of insulin-dependent diabetes mellitus in pet dogs using “Neo-Islets,” aggregates of adipose stem and pancreatic islet cells (INAD 012-776).  PLOS ONE. 2019; 14(9), e0218688. doi:10.1371/journal.pone.0218688

Schott, J. W., León-Rico, D., Ferreira, C. B., Buckland, K. F., Santilli, G., Armant, M. A., Schambach, A., Cavazza, A., Thrasher, A. J.  Enhancing Lentiviral and Alpharetroviral Transduction of Human Hematopoietic Stem Cells for Clinical Application.  Molecular Therapy – Methods & Clinical Development. 2019; 14, 134-147.  doi:10.1016/j.omtm.2019.05.015

Li, R., Johnson, R., Yu, G., McKenna, D. H., Hubel, A.  Preservation of cell-based immunotherapies for clinical trials.  Cytotherapy. 2019; 21(9), 943-957.  doi:10.1016/j.jcyt.2019.07.004

Kolundzic, N., Khurana, P., Devito, L., Jeriha, J., Marx, J., Hobbs, C., Wong, X. F. C. C., Common, J. E., Liovic, M., Dubrac, S., Gruber, R., Schmuth, M., Mauro, T. M., Ilic, D.  Induced pluripotent stem cell line heterozygous for p.R501X mutation in filaggrin: KCLi003-A.  Stem Cell Research. 2019; 39, 101527.  doi:10.1016/j.scr.2019.101527

Coeshott, C., Vang, B., Jones, M., Nankervis, B.  Large-scale expansion and characterization of CD3+ T-cells in the Quantum® Cell Expansion System.  Journal Of Translational Medicine. 2019; 17(1):258.  doi:10.1186/s12967-019-2001-5

Vedvyas, Y., McCloskey, J. E., Yang, Y., Min, I. M., Fahey, T. J., Zarnegar, R., Hsu, Y. S., Hsu, J., Besien, K. V., Gaudet, I., Law, P., Kim, N. J., Hofe, E. V., Jin, M. M.  Manufacturing and preclinical validation of CAR T cells targeting ICAM-1 for advanced thyroid cancer therapy.  Scientific Reports. 2019; 9(1).  doi:10.1038/s41598-019-46938-7

Aizarani, N., Saviano, A., Sagar, Mailly, L., Durand, S., Herman, J. S., Pessaux, P., Baumert, T. F., Grün, D.   A human liver cell atlas reveals heterogeneity and epithelial progenitors.  Nature. 2019 Jul 10.  doi:10.1038/s41586-019-1373-2

Garcia, V. J., Rushton, D. J., Tom, C. M., Allen, N. D., Kemp, P. J., Svendsen, C. N., Mattis, V. B.  Huntington’s Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support.  Frontiers In Neuroscience. 2019; 13.  doi:10.3389/fnins.2019.00669

Tang, Y., Tan, S. A., Iqbal, A., Li, J., Glover, S. C.  STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn’s Disease.  Journal Of Immunology Research. 2019; 1-10.  doi:10.1155/2019/9406146

Arazi, A., Rao, D. A., Berthier, C. C., Davidson, A., Liu, Y., Hoover, P. J., Chicoine, A., Eisenhaure, T. M., Jonsson, A. H., Li, S., Lieb, D. J., Zhang, F., Slowikowski, K., Browne, E. P., Noma, A., Sutherby, D., Steelman, S., Smilek, D. E., Tosta, P., Apruzzese, W., Massarotti, E., Dall’Era, M., Park, M., Kamen, D. L., Furie, R. A., Payan-Schober, F., Pendergraft, W. F., McInnis, E. A., Buyon, J. P., Petri, M. A., Putterman, C., Kalunian, K. C., Woodle, E. S., Lederer, J. A., Hildeman, D. A., Nusbaum, C., Raychaudhuri, S., Kretzler, M., Anolik, J. H., Brenner, M. B., Wofsy, D., Hacohen, N. and Diamond, B.  The immune cell landscape in kidneys of patients with lupus nephritis.  Nature Immunology. 2019; 20(7), 902-914.  doi:10.1038/s41590-019-0398-x

Schuler, F., Afreen, S., Manzl, C., Häcker, G., Erlacher, M.,Villunger, A.  Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.  EMBO Reports. 2019; e47026.  doi:10.15252/embr.201847026

Cao, X., Yakala, G. K., van den Hil, F. E., Cochrane, A., Mummery, C. L., Orlova, V. V.  Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives.  Stem Cell Reports. 2019; 12(6), 1282-1297.  doi:10.1016/j.stemcr.2019.05.003

Xia, X., Li, H., Satheesan, S., Zhou, J., Rossi, J. J.  Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies.  Journal Of Visualized Experiments. 2019; (143).  doi:10.3791/58255

Chen, L. N., Collins‐Johnson, N., Sapp, N., Pickett, A., West, K., Stroncek, D. F., Panch, S. R.  How do I structure logistic processes in preparation for outsourcing of cellular therapy manufacturing?  Transfusion. August 2019; 59 (8), 2506-2518.  doi:10.1111/trf.15349

Meneghel, J., Kilbride, P., Morris, J. G. and Fonseca, F.  Physical events occurring during the cryopreservation of immortalized human T cells.  PLOS ONE. 2019; 14(5), e0217304.  doi: 10.1371/journal.pone.0217304

Thej, C., Gupta, P.  The Role of Mesenchymal Stromal Cells in the Management of Osteoarthritis of the Knee.  IntechOpen. 2019; Online First.  doi: 10.5772/intechopen.86016

Tappenbeck, N., Schröder, H. M., Niebergall-Roth, E., Hassinger, F., Dehio, U., Dieter, K., Kraft, K., Kerstan, A., Esterlechner, J., Frank, N. Y., Scharffetter-Kochanek, K., Murphy, G. F., Orgill, D. P., Beck, J., Frank, M. H., Ganss, C., Kluth, M. A.  In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials.  Cytotherapy. 2019; 21(5), 546-560.  doi: 10.1016/j.jcyt.2018.12.005

Kuo, D., Ding, J., Cohn, I. S., Zhang, F., Wei, K., Rao, D. A., Rozo, C., Sokhi, U. K., Shanaj, S., Oliver, D. J., Echeverria, A. P., DiCarlo, E. F., Brenner, M. B., Bykerk, V. P., Goodman, S. M., Raychaudhuri, S., Rätsch, G., Ivashkiv, L. B., Donlin, L. T.  HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness.  Science Translational Medicine. 2019; 11(491), eaau8587.  doi:10.1126/scitranslmed.aau8587

Pal, S. K., Moreira, D., Won, H., White, S. W., Duttagupta, P., Lucia, M., Jones, J., Hsu, J., Kortylewski, M.  Reduced T-cell Numbers and Elevated Levels of Immunomodulatory Cytokines in Metastatic Prostate Cancer Patients De Novo Resistant to Abiraterone and/or Enzalutamide Therapy.  International Journal Of Molecular Sciences. 2019; 20(8), 1831.  doi:10.3390/ijms20081831

Adane, B., Ye, H., Khan, N., Pei, S., Minhajuddin, M., Stevens, B. M., Jones, C. L., D’Alessandro, A., Reisz, J. A., Zaberezhnyy, V., Gasparetto, M., Ho, T., Kelly, K. K., Myers, J. R., Ashton, J. M., Siegenthaler, J., Kume, T., Campbell, E. L., Pollyea, D. A., Becker, M. W., Jordan, C. T.  The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.  Cell Reports. 2019; 27(1), 238-254.e6.  doi:10.1016/j.celrep.2019.03.009

Read, E.  Qualification of cellular starting materials for cell-based therapies.  Cell & Gene Therapy Insights 2019; 5(2), 177-196.  doi: 10.18609/cgti.2019.021

Clarke, D., Smith, D.  Managing starting material stability to maximize manufacturing flexibility and downstream efficiency.  Cell & Gene Therapy Insights 2019; 5(2), 303-314.  doi: 10.18609/cgti.2019.033

Roberts, E. L., Dang, T., Lepage, S. I. M., Alizadeh, A. H., Walsh, T., Koch, T. G., Kallos, M. S.  Improved expansion of equine cord blood derived mesenchymal stromal cells by using microcarriers in stirred suspension bioreactors.  Journal Of Biological Engineering. 2019; 13(1).  doi:10.1186/s13036-019-0153-8

Hoffman, M., Gillmor, A., Kunz, D. J., Johnston, M. J., Nikolic, A., Narta, K., Zarrei, M., King, J. C., Ellestad, K., Dang, N. H., Cavalli, F. M. G., Kushida, M., Coutinho, F. J., Zhu, Y., Luu, B., Ma, Y., Mungall, A. J., Moore, R. A., Marra, M. A., Taylor, M. D., Pugh, T. J., Dirks, P. B., Strother, D., Lafay-Cousin, L., Resnick, A. C., Scherer, S. W., Senger, D. L., Simons, B. D., Chan, J. A., Morrissy, A. S., Gallo, M.  Intratumoral genetic and functional heterogeneity in pediatric glioblastoma.  Cancer Research. March 15 2019.  doi:10.1158/0008-5472.can-18-3441

Parikh, K., Antanaviciute, A., Fawkner-Corbett, D., Jagielowicz, M., Aulicino, A., Lagerholm, C., Davis, S., Kinchen, J., Chen, H. H., Alham, N. K., Ashley, N., Johnson, E., Hublitz, P., Bao, L., Lukomska, J., Andev, R. S., Björklund, E., Kessler, B. M., Fischer, R., Goldin, R., Koohy, H., Simmons, A.  Colonic epithelial cell diversity in health and inflammatory bowel disease.  Nature. 2019; 567, 49-55.  doi:10.1038/s41586-019-0992-y

Paitazoglou, C., Bergmann, M. W., Vrtovec, B., Chamuleau, S. A. J., van Klarenbosch, B., Wojakowski, W., Michalewska-Wudarczyk, A., Gyöngyösi, M., Ekblond, A., Haack-Sørensen, M., Jaquet, K., Vrangbæk, K., Kastrup, J., SCIENCE Investigators.  Rationale and design of the European multicentre study on Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE).  European Journal of Heart Failure. 2019; 21(8), 1032-1041.  doi:10.1002/ejhf.1412

Zhong, W., Xu, M., Li, C., Zhu, B., Cao, X., Li, D., Chen, H., Hu, C., Li, R., Luo, C., Pan, G., Zhang, W., Lai, C., Wang, T., Du, X., Chen, H., Xu, G., Olkkonen, V. M., Lei, P., Xu, J., Yan, D.  ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells.  Cell Reports. 2019; 26(8), 2166-2177.e9.  doi:10.1016/j.celrep.2019.01.082

Jung, J., Buisman, S. C., Weersing, E., Dethmers-Ausema, A., Zwart, E., Schepers, H., Dekker, M. R., Lazare, S. S., Hammerl, F., Skokova, Y., Kooistra, S. M., Klauke, K., Poot, R. A., Bystrykh, L. V., de Haan, G. CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions. Cell Reports. 2019; 26(7), 1906-1918.e8. doi:10.1016/j.celrep.2019.01.050

Stroncek, D., Mathew, A., & McKenna, D. Cell therapies for trauma and critical care medicine: critical issues in translation for cellular and novel therapies in trauma and critical care. Transfusion. 2019; 59(S1), 854-857. doi:10.1111/trf.14832

Marín Morales, J. M., Münch, N., Peter, K., Freund, D., Oelschlägel, U., Hölig, K., Böhm, T., Flach, A., Keßler, J., Bonifacio, E., Bornhäuser, M., Fuchs, A.  Automated Clinical Grade Expansion of Regulatory T Cells in a Fully Closed System. Frontiers In Immunology. 2019; 10:38.  doi:10.3389/fimmu.2019.00038

Kim, M., Audet, J.   On-demand serum-free media formulations for human hematopoietic cell expansion using a high dimensional search algorithm.  Communications Biology. 2019; 2:48. doi:10.1038/s42003-019-0296-7

GE Healthcare.  Closed and semi-automated processing of CAR T cells.

Charlesworth, C. T., Deshpande, P. S., Dever, D. P., Camarena, J., Lemgart, V. T., Cromer, M. K., Vakulskas, C. A., Collingwood, M. A., Zhang, L., Bode, N. M., Behlke, M. A., Dejene, B., Cieniewicz, B., Romano, R., Lesch, B. J., Gomez-Ospina, N., Mantri, S., Pavel-Dinu, M., Weinberg, K. I., Porteus, M. H.  Identification of Pre-Existing Adaptive Immunity to Cas9 Proteins in Humans.  Nature Medicine. 2019; 25, 249-254.  doi:10.1038/s41591-018-0326-x

Roddie, C., O’Reilly, M., Dias Alves Pinto, J., Vispute, K., Lowdell, M.  Manufacturing chimeric antigen receptor T cells: issues and challenges.  Cytotherapy. March 2019; 21(3), 327-340.  doi: 10.1016/j.jcyt.2018.11.009

Sharma, R., Khristov, V., Rising, A., Jha, B. S., Dejene, R., Hotaling, N., Li, Y., Stoddard, J., Stankewicz, C., Wan, Q., Zhang, C., Campos, M. M., Miyagishima, K. J., McGaughey, D., Villasmil, R., Mattapallil, M., Stanzel, B., Qian, H., Wong, W., Chase, L., Charles, S., McGill, T., Miller, S., Maminishkis, A., Amaral, J., Bharti, K. Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs. Science Translational Medicine. 2019; 11(475), eaat5580. doi:10.1126/scitranslmed.aat5580

Mitsunaga, S., Shioda, K., Isselbacher, K. J., Hanna, J. H., Shioda, T.  Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells.  J. Vis. Exp. 2019; (143), e58297.  doi:10.3791/58297 (2019).

Kozbial, A., Weinstein, H., Murthy, S. K., Rossi, J. M.  Scale-up of a perfusion-based dendritic cell generation process.  Cell Gene Therapy Insights 2018; 4(11), 1117-1130.  doi: 10.18609/cgti.2018.110

Murad, J. P., Kozlowska, A. K., Lee, H. J., Ramamurthy, M., Chang, W., Yazaki, P., Colcher, D., Shively, J., Cristea, M., Forman, S. J., Priceman, S. J.  Effective Targeting of TAG72+ Peritoneal Ovarian Tumors via Regional Delivery of CAR-Engineered T Cells.  Front. Immunol. 2018; 9:2268.  doi:10.3389/fimmu.2018.02268

Demmerath, E., Bohler, S., Kunze, M., Erlacher, M.  In Vitro And In Vivo Evaluation Of Possible Pro-Survival Activities Of PGE2, EGF, TPO And FLT3L On Human Hematopoiesis.  Haematologica. November 2018; haematol.2018.191569.  doi:10.3324/haematol.2018.191569

Wagh, K., Kreider, E. F., Li, Y., Barbian, H. J., Learn, G. H., Giorgi, E., Hraber, P. T., Decker, T. G., Smith, A. G., Gondim, M. V., Gillis, L., Wandzilak, J., Chuang, G., Rawi, R., Cai, F., Pellegrino, P., Williams, I., Overbaugh, J., Gao, F., Kwong, P. D., Haynes, B. F., Shaw, G. M., Borrow, P., Seaman, M. S., Hahn, B. H., Korber, B. Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth. Cell Reports. 2018; 25(4), 893-908. doi:10.1016/j.celrep.2018.09.087

Fonseka, C. Y., Rao, D. A., Teslovich, N. C., Korsunsky, I., Hannes, S. K., Slowikowski, K., Gurish, M. F., Donlin, L. T., Lederer, J. A., Weinblatt, M. E., Massarotti, E. M., Coblyn, J. S., Helfgott, S. M., Todd, D. J., Bykerk, V. P., Karlson, E. W., Ermann, J., Lee, Y. C., Brenner, M. B., Raychaudhuri, S. Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis. Science Translational Medicine. 2018; 10(463), eaaq0305. doi:10.1126/scitranslmed.aaq0305

Kuo-Jen Wu, Seong-Jin Yu, Chia-Wen Chiang, Yu-Wei Lee, B Linju Yen, Pei-Chi Tseng, Chun-Sen Hsu, Li-Wei Kuo, Yun Wang.  Neuroprotective Action of Human Wharton’s Jelly-Derived Mesenchymal Stromal Cell Transplants in a Rodent Model of Stroke.  Cell Transplant. 2018 Oct 4:963689718802754.  doi:10.1177/0963689718802754

Mathew, A. J.  Biopreservation Considerations for Regenerative Medicine GMP Manufacturing; 2018.  https://ebook.liebertpub.com/biolife-solutions/biopreservation-considerations-for-regenerative-medicine-gmp-manufacturing

Sutton, M., Kaur, S., Brown, K., Skiles, M., Folz, M., Caplan, A., and Bonfield, T.  Anti-Inflammatory Therapeutic Development and Optimization of Umbilical Cord Tissue Derived Mesenchymal Stem Cells.  Journal Of Stem Cell Research & Therapy. 2018; 8(8), 1-9.  doi: 10.4172/2157-7633.1000435

Zhang, Z., Wilson, N. A., Chinnadurai, R., Panzer, S. E., Redfield, R. R., Reese, S. R., Galipeau, J., Djamali, A.  Autologous Mesenchymal Stromal Cells Prevent Transfusion-elicited Sensitization and Upregulate Transitional and Regulatory B Cells. Transplantation Direct. 2018 Sep; 4(9): e387.  doi:10.1097/txd.0000000000000827

Andriolo, G., Provasi, E., Lo Cicero, V., Brambilla, A., Soncin, S., Torre, T., Milano, G., Biemmi, V., Vassalli, G., Turchetto, L., Barile, L. and Radrizzani, M.  Exosomes From Human Cardiac Progenitor Cells for Therapeutic Applications: Development of a GMP-Grade Manufacturing Method.  Front. Physiol. 2018; 9:1169.  doi:10.3389/fphys.2018.01169

Jin, J., Tarrant, R. D., Bolam, E. J., Angell-Manning, P., Soegaard, M., Pattinson, D. J., Dulal, P., Silk, S. E., Marshall, J. M., Dabbs, R. A., Nugent, F. L., Barrett, J. R., Hjerrild, K. A., Poulsen, L., Jørgensen, T., Brenner, T., Baleanu, I. N., Parracho, H. M., Tahiri-Alaoui, A., Whale, G., Moyle, S., Payne, R. O., Minassian, A. M., Higgins, M. K., Detmers, F. J., Lawrie, A. M., Douglas, A. D., Smith, R., de Jongh, W. A., Berrie, E., Ashfield, R. and Draper, S. J.  Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells.  Npj Vaccines. 2018; 3:32, 1-13.  doi:10.1038/s41541-018-0071-7

HemaCare.  Regulatory T Cell Modulation of Immune Suppression.  August 2018, 1-3

George, M. J., Prabhakara, K., Toledano-Furman, N. E., Wang, Y., Gill, B. S., Wade, C. E., Olson, S. D. and Cox, C. S.  Clinical Cellular Therapeutics Accelerate Clot Formation.  STEM CELLS Translational Medicine (2018).  doi:10.1002/sctm.18-0015

van de Loosdrecht, A. A., van Wetering, S., Santegoets, S. J. A. M., Singh, S. K., Eeltink, C. M., den Hartog, Y., Koppes, M., Kaspers, J., Ossenkoppele, G. J., Kruisbeek, A. M., de Gruijl, T. D.  A novel allogeneic off-the-shelf dendritic cell vaccine for post-remission treatment of elderly patients with acute myeloid leukemia.  Cancer Immunology, Immunotherapy. 2018; 67(10), 1505-1518.  doi:10.1007/s00262-018-2198-9

Barrachina, L., Romero, A., Zaragoza, P., Rodellar, C., Vázquez, F.   Practical considerations for clinical use of mesenchymal stem cells: From the laboratory to the horse.  The Veterinary Journal. 2018; 238, 49-57.  doi:10.1016/j.tvjl.2018.07.004

Donlin, L. T., Rao, D. A., Wei, K., Slowikowski, K., McGeachy, M. J., Turner, J. D., Meednu, N., Mizoguchi, F., Gutierrez-Arcelus, M., Lieb, D. J., Keegan, J., Muskat, K., Hillman, J., Rozo, C., Ricker, E., Eisenhaure, T. M., Li, S., Browne, E. P., Chicoine, A., Sutherby, D., Noma, A., Nusbaum, C., Kelly, S., Pernis, A. B., Ivashkiv, L. B., Goodman, S. M., Robinson, W. H., Utz, P. J., Lederer, J. A., Gravallese, E. M., Boyce, B. F., Hacohen, N., Pitzalis, C., Gregersen, P. K., Firestein, G. S., Raychaudhuri, S., Moreland, L. W., Holers, M., Bykerk, V. P., Filer, A., Boyle, D. L., Brenner, M. B. and Anolik, J. H.  Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue.  Arthritis Res Ther. 2018; 20: 139.  doi: 10.1186/s13075-018-1631-y

Hamilton, C. A., Young, R., Jayaraman, S., Sehgal, A., Paxton, E., Thomson, S., Katzer, F., Hope, J., Innes, E., Morrison, L. J. and Mabbott, N. A.  Development of in vitro enteroids derived from bovine small intestinal crypts.  Veterinary Research. 2018; 49(1).  doi:10.1186/s13567-018-0547-5

Yu, M. S., Spiering, S., Colas, A. R.  Generation of First Heart Field-like Cardiac Progenitors and Ventricular-like Cardiomyocytes from Human Pluripotent Stem Cells.  J. Vis. Exp. 2018; (136).  doi:10.3791/57688

Aijaz, A., Li, M., Smith, D., Khong, D., LeBlon, C., Fenton, O. S., Olabisi, R. M., Libutti, S., Tischfield, J., Maus, M. V., Deans, R., Barcia, R. N., Anderson, D. G., Ritz, J., Preti, R., Parekkadan, B. Biomanufacturing for clinically advanced cell therapies.  Nature Biomedical Engineering 2018; 2(6), 362-376. doi:10.1038/s41551-018-0246-6

Pham, H., Tonai, R., Wu, M., Birtolo, C., Chen, M.  CD73, CD90, CD105 and Cadherin-11 RT-PCR Screening for Mesenchymal Stem Cells from Cryopreserved Human Cord Tissue.   Int. J. Stem Cells 2018; 11(1): 26-38.  doi:10.15283/ijsc17015

HemaCare. CD34+ Hematopoietic Stem and Progenitor Cells From Different Tissue Sources For Cell Therapy. May 2018: 1-4

Fernandopulle, M., Prestil, R., Grunseich, C., Wang, C., Gan, L., Ward, M. Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons. Current Protocols In Cell Biology 2018; 79(1), e51. doi:10.1002/cpcb.51

Lacher, M. D., Bauer, G., Fury, B., Graeve, S., Fledderman, E. L., Petrie, T. D., Coleal-Bergum, D. P., Hackett, T., Perotti, N. H., Kong, Y. Y., Kwok, W. W., Wagner, J. P., Wiseman, C. L., Williams, W. V. SV-BR-1-GM, A Clinically Effective GM-CSF-Secreting Breast Cancer Cell Line, Expresses An Immune Signature And Directly Activates CD4+ T Lymphocytes. Frontiers In Immunology 2018; 9(776), 1-23. doi:10.3389/fimmu.2018.00776

Lou Juliano, George Eastwood, Todd Berard, Aby J. Mathew. The Importance of Collection, Processing and Biopreservation Best Practices in Determining CAR-T Starting Material Quality. Cell Gene Therapy Insights 2018; 4(4), 327-336. doi: 10.18609/cgti.2018.032

Hiraishi, S., Schol, J., Sakai, D., Nukaga, T., Erickson, I., Silverman, L., Foley, K., Watanabe, M. Discogenic cell transplantation directly from a cryopreserved state in an induced intervertebral disc degeneration canine model. JOR Spine. (2018); 1(2), e1013. doi:10.1002/jsp2.1013

Rajamani, U., Gross, A. R., Hjelm, B. E., Sequeira, A., Vawter, M. P., Tang, J., Gangalapudi, V., Wang, Y., Andres, A. M., Gottlieb, R. A., Sareen, D. Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses.  Cell Stem Cell 2018, Vol. 22(5), 698-712.e9. doi: 10.1016/j.stem.2018.03.009

Hung, C., Xu, X., Li, L., Ma, Y., Jin, Q., Viley, A., Allen, C., Natarajan, P., Shivakumar, R., Peshwa, M. V. and Emens, L. A. Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA–Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy. Human Gene Therapy. 2018; 29(5), 614-625. doi:10.1089/hum.2017.080

Habiel, D., Espindola, M., Coelho, A., & Hogaboam, C. Modeling Idiopathic Pulmonary Fibrosis in Humanized SCID Mice. The American Journal of Pathology 2018 Apr; 188(4): 891-903. doi: 10.1016/j.ajpath.2017.12.020

Yongshun Lin, Huimin Liu, Michael Klein, John Ostrominski, So Gun Hong, Ravi Chandra Yada, Guibin Chen, Keron Navarengom, Robin Schwartzbeck, Hong San, Zu-Xi Yu, Chengyu Liu, Kaari Linask, Jeanette Beers, Lugui Qiu, Cynthia E. Dunbar, Manfred Boehm, Jizhong Zou. Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs. Scientific Reports 2018 Vol. 8(1): 1-16. doi:10.1038/s41598-018-24074-y

McCreedy, B. J., Senyukov, V. V., Nguyen, K. T.   Off the shelf T cell therapies for hematologic malignancies.  Best Practice & Research Clinical Haematology 2018; 31(2), 166-175.  doi: 10.1016/j.beha.2018.03.001.

Brown, Zhou, McIntosh, Norman, Lou, Biermann, Sullivan, Kamp, Thomson, Anagnostopoulos, Burlingham. A Humanized Mouse Model Generated Using Surplus Neonatal Tissue. Stem Cell Reports (2018). doi:10.1016/j.stemcr.2018.02.011

Rouzbeh R. Taghizadeh, Kyle J. Cetrulo, Curtis L. Cetrulo. Collagenase Impacts the Quantity and Quality of Native Mesenchymal Stem/Stromal Cells Derived during Processing of Umbilical Cord Tissue. Cell Transplantation 2018, Vol. 27(1), 181–193. doi: 10.1177/0963689717744787

Srinivasana A, Changa S-Y, Zhange S, Toh WS, Toh Y-C. Substrate stiffness modulates the multipotency of human neural crest derived ectomesenchymal stem cells via CD44 mediated PDGFR signaling. Biomaterials 2018, Vol. 167, 153-167. doi:10.1016/j.biomaterials.2018.03.022

Wagner, J., Kline, C. L., Zhou, L., Campbell, K. S., MacFarlane, A. W., Olszanski, A. J., Cai, K. Q., Hensley, H. H., Ross, E. A., Ralff, M. D., Zloza, A., Chesson, C. B., Newman, J. H., Kaufman, H., Bertino, J., Stein, M., El-Deiry, W. S.  Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment.  J Clin Invest. 2018; 128(6), 2325-2338.  doi:10.1172/jci96711

Ivanics, Bergquist, Liu, Kim, Kang, Katz, Rios Perez, Thomas, Fleming, Truty. Patient-derived xenograft cryopreservation and reanimation outcomes are dependent on cryoprotectant type. Laboratory Investigation (2018). doi:10.1038/s41374-018-0042-7

Baradez, M., Biziato, D., Hassan, E., Marshall, D.  Application of Raman Spectroscopy and Univariate Modelling As a Process Analytical Technology for Cell Therapy Bioprocessing. Front. Med. 2018; 5(47), 1-14. doi:10.3389/fmed.2018.00047

Hardin, Vreeland, Clifton, Hale, Herbert, Greene, Jackson, Berry, Nichols, Yin, Yu, Wagner, Peoples. Tumor lysate particle loaded dendritic cell vaccine: preclinical testing of a novel personalized cancer vaccine. Immunotherapy (2018) 10(5), 373–382. https://doi.org/10.2217/imt-2017-0114

Mattar, M., McCarthy, C. R., Kulick, A. R., Qeriqi, B., Guzman, S., de Stanchina, E. Establishing and Maintaining an Extensive Library of Patient-Derived Xenograft Models. Frontiers in Oncology 2018, 8 (Article 19): 1-18. doi:10.3389/fonc.2018.00019

Sampath, Won, Massarelli, Li, Frankel, Vora, Maghami, Kortylewski. Combined modality radiation therapy promotes tolerogenic myeloid cell populations and STAT3-related gene expression in head and neck cancer patients. Oncotarget, 2018, Vol. 9, (No. 13), pp: 11279-11290 . https://doi.org/10.18632/oncotarget.24397

GE Healthcare Life Sciences. Workflow for primary human NK cell isolation, xeno‑free expansion, harvest, and cryopreservation.

de Smet, M., Lynch, J., Dejneka, N., Keane, M., & Khan, I.  A Subretinal Cell Delivery Method via Suprachoroidal Access in Minipigs: Safety and Surgical Outcomes.  Investigative Opthalmology & Visual Science.  January 2018; 59(1), 311.  doi:10.1167/iovs.17-22233

Griffiths, Habiel, Jaffar, Binder, Darby, Hosking, Skerra, Westall, Hogaboam, Foley. Anti-fibrotic Effects of CXCR4-Targeting i-body AD-114 in Preclinical Models of Pulmonary Fibrosis. Scientific Reports (2018) 8:3212. DOI:10.1038/s41598-018-20811-5

Henrieta Fraser, Niloufar Safinia ,Nathali Grageda, Sarah Thirkell, Katie Lowe, Laura J. Fry, Cristiano Scottá, Andrew Hope, Christopher Fisher, Rachel Hilton, David Game, Paul Harden, Andrew Bushell, Kathryn Wood, Robert I. Lechler, Giovanna Lombardi.  A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials.  Molecular Therapy: Methods & Clinical Development 2018 March; 3:198-209.  doi: 10.1016/j.omtm.2018.01.006

Willie Lin, Yogi Chang-Yo Hsuan, Mao-Tsun Lin, Ting-Wei Kuo, Cheng-Hsien Lin, Yu-Chin Su, Ko-Chi Niu, Ching-Ping Chang, Hung-Jung Lin. Human Umbilical Cord Mesenchymal Stem Cells Preserve Adult Newborn Neurons and Reduce Neurological Injury after Cerebral Ischemia by Reducing the Number of Hypertrophic Microglia/Macrophages.  Cell Transplantation 2017 Nov; 26(11): 1798–1810. doi: 10.1177/0963689717728936

Gouin, Peck, Antes, Johnson, Li, Vaturi, Middleton, de Couto, Walravens, Rodriguez-Borlado, Smith, Marban, Ibrahim. A comprehensive method for identification of suitable reference genes in extracellular vesicles. JOURNAL OF EXTRACELLULAR VESICLES, 2017 VOL. 6, 1347019. https://doi.org/10.1080/20013078.2017.1347019

Montanari, E., Pimenta, J., Szabó, L., Noverraz, F., Passemard, S., Meier, R. P. H., Meyer, J., Sidibe, J., Thomas, A., Schuurman, H., Gerber-Lemaire, S., Gonelle-Gispert, C. and Buhler, L. H. Beneficial Effects of Human Mesenchymal Stromal Cells on Porcine Hepatocyte Viability and Albumin Secretion. Journal of Immunology Research 2018, Article ID 1078547: 1-13. doi:10.1155/2018/1078547

Skiles, M., Brown, K., Tatz, W., Swingle, K., & Brown, H. Quantitative analysis of composite umbilical cord tissue health using a standardized explant approach and an assay of metabolic activity. Cytotherapy 2018, 20(4), 564-575. https://doi.org/10.1016/j.jcyt.2018.01.001

Petersen, Hassan, Morris, Jeffery, Lee, Jagirdar, Staton, Raikar, Spencer, Sulchek, Flowers, Waller. Improving T-cell expansion and function for adoptive T-cell therapy using ex vivo treatment with PI3Kδ inhibitors and VIP antagonists. Blood Advances 2018 2:210-223. DOI 10.1182/bloodadvances.2017011254

Zheng, Hu, Wolfe, Gonsalves, Ren, Khawli, Kaslow, Epstein. Lym-1 Chimeric Antigen Receptor T Cells Exhibit Potent Anti Tumor Effects against B-Cell Lymphoma. Int. J. Mol. Sci. 2017, 18, 2773. doi:10.3390/ijms18122773

Abazari A, Hawkins BJ, Clarke DM, Mathew AJ. Biopreservation Best Practices: A Cornerstone in the Supply Chain of Cell-based Therapies – MSC Model Case Study.  Cell Gene Therapy Insights 2017; 3(10), 853-871. DOI: 10.18609/cgti.2017.082

Lin, Hsuan, Su, Lin, Lin, Chen, Chang, Lin. CD34− human placenta-derived mesenchymal stem cells protect against heat stroke mortality in rats.  Oncotarget, 2018, Vol. 9, (No. 2), pp: 1992-2001

Weber, Romeo, Dolley-Sonneville. Human Mesenchymal Stem Cell Growth on Corning Denatured Collagen Dissolvable Microcarriers in a 5L Bioreactor. Corning Incorporated, Life Sciences, Corning, NY USA

Zeng, Tang, Toh, Wang. Generation of “Off-the-Shelf” Natural Killer Cells from Peripheral Blood Cell-Derived Induced Pluripotent Stem Cells. Stem Cell Reports Vol. 9 1–17 December 12, 2017. https://doi.org/10.1016/j.stemcr.2017.10.020

Baust, Campbell, Harbell. Best practices for cryopreserving, thawing, recovering, and assessing cells. In Vitro Cell.Dev.Biol.—Animal. DOI 10.1007/s11626-017-0201-y

Princeman, Tilakawardane, Jeang, Aguilar, Murad, Park, Chang, Ostberg, Neman, Jandial, Portnow, Forman, Brown. Regional Delivery of Chimeric Antigen Receptor– Engineered T Cells Effectively Targets HER2þ Breast Cancer Metastasis to the Brain. Clin Cancer Res. 2017 Oct 23. doi: 10.1158/1078-0432.CCR-17-2041

Nham, Poznanski, Fan, Vahedi, Shenouda, Lee, Chew, Hogg, Lee, Ashlar. Ex Vivo-expanded Natural Killer Cells Derived From Longterm Cryopreserved Cord Blood are Cytotoxic Against Primary Breast Cancer Cells. Journal of Immunotherapy: Post Author Corrections: November 17, 2017. doi: 10.1097/CJI.0000000000000192

Kastrup, Haack-Sorensen, Juhl, Sondergaard, Follin, Lund, Johansen, Qayyum, Mathiasen, Jorgenson, Helqvist, Elberg, Bruunsgaard, Ekblond. Cryopreserved Off-the-Shelf Allogeneic Adipose-Derived Stromal Cells for Therapy in Patients with Ischemic Heart Disease and Heart Failure—A Safety Study. STEM CELLS TRANSLATIONAL MEDICINE 2017; 6:1963–1971. https://dx.doi.org/10.1002/sctm.17-0040

Liao, Choi, Vojnits, Xue, Aroom, Meng, Pan, Hetz, Corkins, Hughes, Triolo, Johnson, Moise, Lally, Cox, Li. Tissue Engineering to Repair Diaphragmatic Defect in a Rat Model. Stem Cells International Volume 2017, Article ID 1764523, 12 pages. https://doi.org/10.1155/2017/1764523.

Lim R, Hodge A, Moore G, Wallace E, Slevert W. A Pilot Study Evaluating the Safety of Intravenously Administered Human Amnion Epithelial Cells for the Treatment of Hepatic Fibrosis. Front. Pharmacol. 8:549.doi: 10.3389/fphar.2017.00549

Akimova, T., Zhang, T., Negorev, D., Singhal, S., Stadanlick, J., Rao, A., Annunziata, M., Levine, M. H., Beier, U. H., Diamond, J. M., Christie, J. D., Albelda, S. M., Eruslanov, E. B. and Hancock, W. W.   Human lung tumor FOXP3+ Tregs upregulate four “Treg-locking” transcription factors.  JCI Insight. 2017; 2(16).  doi: 10.1172/jci.insight.94075

Roberts, Haupt, Tucker, Grancharova, Arakaki, Fuqua, Nelson, Hookway, Ludmann, Mueller, Yang, Horwitz, Rafelski, Gunawardane. Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization. Mol Biol Cell. 2017 Oct 15; 28(21): 2854-2874. doi: 10.1091/mbc.E17-03-0209

Laskin, Jiao, Bularte, Amaral, Furth, Akimova, Hancock, Levine, Reese, Beier. The Effects of Tacrolimus on T-Cell Proliferation Are Short-Lived: A Pilot Analysis of Immune Function Testing. Transplant Direct. 2017 Aug; 3(8): e199. doi: 10.1097/TXD.0000000000000715

Thompson, Schryver, Ehrhardt. Cell therapy post-production technologies: a select review of key innovations in the field. Cell Gene Therapy Insights 2017; 433-441.DOI: 10.18609/cgti.2017.049

Akimova, T., Levine, M. H., Beier, U. H., and Hancock, W. W.  Standardization, Evaluation, and Area-Under-Curve Analysis of Human and Murine Treg Suppressive Function.  Methods Mol Biol. 2016; 1371: 43–78.  doi:10.1007/978-1-4939-3139-2_4

Dustin R. Wakeman, Benjamin M. Hiller, David J. Marmion, Christopher W. McMahon, Grant T. Corbett, Kile P. Mangan, Junyi Ma, Lauren E. Little, Zhong Xie, Tamara Perez-Rosello, Jaime N. Guzman, D. James Surmeier, and Jeffrey H. Kordower. Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo. Stem Cell Reports j Vol. 9 j 1–13 j July 11, 2017. https://dx.doi.org/10.1016/j.stemcr.2017.04.033

Fuller, Gonzalez-Molina, Erro, Mendonca, Chalmers, Awan, Poirier, Selden. Applications and optimization of cryopreservation technologies to cellular therapeutics. Cell & Gene Therapy Insights – ISSN: 2059-7800. DOI: 10.18609/cgti.2017.038

Hawkins B, Abazari A, Mathew A. Biopreservation Best Practices for Regenerative Medicine GMP Manufacturing & Focus on Optimized Biopreservation Media. Cell & Gene Therapy Insights – ISSN: 2059-7800. DOI: 10.18609/cgti.2017.035

Hsu, Prigent, Dollet, Ravau, Larbanoix, Simaeys, Bol, Gregoire, Goldman, Deblandre, Najimi, Sokal, Lombard. Long-term In Vivo Monitoring of Adult-Derived Human Liver Stem/Progenitor Cells by Bioluminescence Imaging, Positron Emission Tomography, and Contrast-Enhanced Computed Tomography. STEM CELLS AND DEVELOPMENT (Original Research Report). DOI: 10.1089/scd.2016.0338

Jeremy M. Crook and Tomaskovic-Crook (eds.), Stem Cell Banking: Concepts and Protocols, Methods in Molecular Biology, vol. 1590. doi: 10.1007/978-1-4939-6921-0_15, © Springer Science+Business Media LLC 2017

Huang, Khan, Au, Barber, López-Vásquez, Prokopishyn, Boutin, Rothe, Rip, Abaoui, Nagree, Dworski, Schambach, Keating, West, Klassen, Turner, Sirrs, Rupar, Auray-Blais, Foley, Medin. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease. Molecular Therapy: Methods & Clinical Development Vol. 5 June 2017. doi:  10.1016/j.omtm.2017.05.003

Singh N, Barnes S, Kennedy S, Adams J. Experimental evaluation of cryopreservative solutions to maintain in vitro and in vivo infectivity of P. berghei sporozoites. PLOS ONE. https://doi.org/10.1371/journal.pone.0177304

Fraser, Pass, Burgoyne, Atkinson, Bailey, Laurie, McGowan, Hamid, Moore, Dwyer, Turner, Forbes, Campbell. Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis. Cytotherapy 2017; 19: 1113–1124. doi: 10.1016/j.jcyt.2017.05.009

Harper, Lloyd, Dimasi, Toader, Marwood, Lewis, Bannister, Jovanovic, Fleming, d’Hooge, Mao, Marrero, Korade, Strout, Xu, Chen, Wetzel, Breen, van Vlerken-Ysla, Jalla, Rebelatto, Zhong, Hurt, Hinrichs, Huang, Howard, Tice, Hollingsworth, Herbst, Kamal. Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine Conjugated Antibody–Drug Conjugate Targeting 5T4. Mol Cancer Ther; 16(8) August 2017. DOI: 10.1158/1535-7163.MCT-16-0825

Sinden J, Hicks C, Stroemer P, Vishnubhatla I, Corteling R. Human Neural Stem Cell Therapy for Chronic Ischemic Stroke: Charting Progress From Laboratory to Patients. Stem Cells Dev. 2017 Jul 1;26(13):933-947. doi: 10.1089/scd.2017.0009

Tallmadge, Miller, Parry, Felippe. Antigen-specific immunoglobulin variable region sequencing measures humoral immune response to vaccination in the equine neonate. PLoS ONE 12 (5): e0177831. https://doi.org/10.1371/journal

Worsham, D. N., Reems, J.-A., Szczepiorkowski, Z. M., McKenna, D. H., Leemhuis, T., Mathew, A. J., Cancelas, J. A. and Biomedical Excellence for Safer Transfusion (BEST) Collaborative Group. Clinical methods of cryopreservation for donor lymphocyte infusions vary in their ability to preserve functional T-cell subpopulations. Transfusion (Pre-Print) doi:10.1111/trf.14112.

Zavatti, Beretti, Casciaro, Comitini, Franchi, Barbieri, Bertoni, De Pol, La Sala, Maraud. Development of a novel method for amniotic fluid stem cell storage. Cytotherapy, 2017; 19: 1002–1012; DOI: https://dx.doi.org/10.1016/j.jcyt.2017.04.006

Baust J, Snyder K, Van Buskirk R, Baust J. Integrating Molecular Control to Improve Cryopreservation Outcome. Biopreservation and Biobanking Volume 15, Number 2, 2017. DOI: 10.1089/bio.2016.0119

Howard R. Seay, Amy L. Putnam, Judit Cserny, Amanda L. Posgai, Emma H. Rosenau, John R. Wingard, Kate F. Girard, Morey Kraus, Angela P. Lares, Heather L. Brown, Katherine S. Brown, Kristi T. Balavage, Leeana D. Peters, Ashley N. Bushdorf, Mark A. Atkinson, Jeffrey A. Bluestone, Michael J. Haller, Todd M. Brusk. Expansion of Human Tregs from Cryopreserved Umbilical Cord Blood for GMP-Compliant Autologous Adoptive Cell Transfer Therapy. Molecular Therapy: Methods & Clinical Development Vol. 4 March 2017 DOI: https://dx.doi.org/10.1016/j.omtm.2016.12.003

Agudelo D, Bozoyan L, Duringer A, Huard C, Carter S, Loehr J, Synodinou D, Drouin M, Salsman J, Dellaire G, Laganiere J, Doyon Y. Marker-free coselection for CRISPR-driven genome editing in human cells. Nature Methods 14, 615 – 620; 2017 doi:10.1038/nmeth.4265

Kai-Hsin Chang, Sarah E. Smith, Timothy Sullivan, Kai Chen, Qianhe Zhou, Jason A. West, Mei Liu, Yingchun Liu, Benjamin F. Vieira, Chao Sun, Vu P. Hong, Mingxuan Zhang, Xiao Yang, Andreas Reik, Fyodor D. Urnov, Edward J. Rebar, Michael C. Holmes, Olivier Danos, Haiyan Jiang, and Siyuan Tan. Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34+ Hematopoietic Stem and Progenitor Cells. 138 Molecular Therapy: Methods & Clinical Development Vol. 4 March 2017. doi:  10.1016/j.omtm.2016.12.009

Kota, Prabhakara, Tolendano-Furman, Bhattarai, Chen, DiCarlo, Smith, Triolo, Wenzel, Cox, Olson. Prostaglandin E2 Indicates Therapeutic Efficacy of Mesenchymal Stem Cells in Experimental Traumatic Brain Injury. Stem Cells. 2017 May;35(5):1416-1430.  doi: 10.1002/stem.2603

Ross, S. B., Fraser, S. T., Nowak, N. and Semsarian, C.  Generation of induced pluripotent stem cells (iPSCs) from a hypertrophic cardiomyopathy patient with the pathogenic variant p.Val698Ala in beta-myosin heavy chain ( MYH7 ) gene.  Stem Cell Research. 2017; 20, 88-90.  doi:10.1016/j.scr.2017.02.015

Ross, S. B., Fraser, S. T., Bagnall, R. D. and Semsarian, C.  Peripheral blood derived induced pluripotent stem cells (iPSCs) from a female with familial hypertrophic cardiomyopathy.  Stem Cell Research. 2017; 20, 76-79.  doi:10.1016/j.scr.2017.02.016

Hradilova N, Sadilkova L, Palata O, Mysikova D, Mrazkova H, Lischke R, Spisek R, Adkins I. Generation of dendritic cell-based vaccine using high hydrostatic pressure for non-small cell lung cancer immunotherapy  PLoS ONE 12(2): e0171539. doi:10.1371/journal.pone.0171539

Rao, Gurish, Marshall, Slowikowski, Fonseka, Liu, Donlin, Henderson, Wei, MizoGuchi, Teslovich, Weinblatt, Massarotti, Coblyn, Helfgott, Lee, Todd, Bykerk, Goodman, Pernis, Ivashkiv, Karlson, Nigrovic, Filer, Buckley, Lederer, Raychaudhuri, Brenner. Pathologically expanded peripheral T helper cell subsets drives B cells in rheumatoid arthritis. Nature 542, 110–114 (02 February 2017) doi:10.1038/nature20810

Moussy A, Cosette J, Parmentier R, da Silva C, et al. Integrated time-lapse and single-cell transcription studies highlight the variable and dynamic nature of human hematopoietic cell fate commitment. PLoS Biol 15 (7): e2001867 dos: https://doi.org/10.1101/101428

Kunkele A, Taraseviciute A, Finn L, Johnson A, et al. Preclinical Assessment of CD171-Directed CAR T-cell Adoptive Therapy for Childhood Neuroblastoma: CE7 Epitope Target Safety and Product Manufacturing Feasibility Clin Cancer Res; 23(2) January 15, 2017 DOI: 10.1158/1078-0432.CCR-16-0354

Kadota S, Pabon L, Reinecke H, Murry C. In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts. Stem Cell Reports (2016) DOI: https://dx.doi.org/10.1016/j.stemcr.2016.10.009

Gardner R, Finney O, Annesley C, Brakke H, Summers C, Leger K, Bleakley M, Brown C, Mgebroff S, Spratt K, Hoglund V, Lindgren C, Oron A, Li D, Riddell S, Park J, Jensen M. Intent to treat leukemia remission by CD19CAR T cells of defined formulation and dose in children and young adults. Blood 2017 :blood-2017-02-769208. doi: https://doi.org/10.1182/blood-2017-02-769208

Brown C, Alizadeh D, Starr R, Weng L, Wagner J, et al. Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy. N Engl J Med 2016;375:2561-9 DOI: 10.1056/NEJMoa1610497

Herzog R, Nichols T, Su J, Zhang B, Sherman A, et al. Oral Tolerance Induction in Hemophilia B Dogs Fed with Transplastomic Lettuce. Molecular Therapy (2016) DOI: https://dx.doi.org/10.1016/j.ymthe.2016.11.009

Aliota M, Dudley D, Newman C, Mohr E, et al. Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques. PLoS Negl Trop Dis 10(12): e0005168 DOI:10.1371/journal.pntd.0005168

Lu T, Pugach O, Somerville R, Rosenberg S, Kochendefer J, Better M, Feldman S A Rapid Cell Expansion Process for Production of Engineered Autologous CAR-T Cell Therapies HUMAN GENE THERAPY METHODS, VOLUME 27 NUMBER 6 DOI: 10.1089/hgtb.2016.120

Broeren M, de Vries M, Bennink M, van Lent P, van der Kraan P, Koenders M, Thurlings R, van de Loo F. Functional Tissue Analysis Reveals Successful Cryopreservation of Human Osteoarthritic Synovium. PLoS ONE 11(11): e0167076. doi:10.1371/journal.pone.0167076

Preininger MK, Singh M, Xu C. Cryopreservation of Human Pluripotent Stem Cell-Derived Cardiomyocytes: Strategies, Challenges, and Future Directions. Adv Exp Med Biol. 2016;951:123-135. DOI: 10.1007/978-3-319-45457-3_10

DiGiusto D, Canno P, Holmes M, Li L, et al. Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells. Molecular Therapy — Methods & Clinical Development 3, Article number: 16067 (2016) doi:10.1038/mtm.2016.67

Bruzos-Cidon C, Castano J, Torrecilla M, Sanchez-Pernaute R, Giorgetti A. Fast and Efficient Neural Conversion of UNIT 1F.15 Human Hematopoietic Cells. Curr. Protoc. Stem Cell Biol. 39:1F.15.1-1F.15.20. doi: 10.1002/cpsc.16

Kevin O’Donnell.  Cell and Gene Therapies in Transit: Caution – Hazards Ahead: The Cell & Gene Therapy Manufacturing Pathway – Part 2.  Cell and Gene Therapy Insights. 2016; 2(2), 271-276.  doi: 10.18609/cgti.2016.031

Bárbara Dias Fernandes. Flexible insect cell platforms for fast production of pseudotyped virus-like particles. Master’s Thesis (2016), University of Lisbon

Gregory MA, D’Alessandro A, Alvarez-Calderon F, Kim J, et al. ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6669-E6678. Epub 2016 Oct 10. DOI:10.1073/pnas.1603876113

Zulfiqar S, Fritz B, Nieweg K. Episomal plasmid-based generation of an iPSC line from an 83-year-old individual carrying the APOE4/4 genotype: i10984. Stem Cell Research 17 (2016) 523–525. doi: 10.1016/j.scr.2016.09.017

Zulfiqar S, Fritz B, Nieweg K. Episomal plasmid-based generation of an iPSC line from a 79-year-old individual carrying the APOE4/4 genotype: i11001. Stem Cell Res. 2016 Sep 23;17(3):544-546. doi: 10.1016/j.scr.2016.09.023

Brady C, Armitage S, Freed B, Duffy M, Gass A, Spellman S, Kurtzber J, Regan D. How transplant centers deal with the dextran shortage: recommendations for comparing alternatives. Transfusion. 2016 Sep 5. [Epub ahead of print]. DOI: 10.1111/trf.13783

Chakravarty T, Makkar RR, Ascheim DD, Traverse JH, Schatz R, DeMaria A, Francis GS, Povsic TJ, Smith RR, Lima JA, Pogoda JM, Marbán L, Henry TD ALLogeneic Heart STem Cells to Achieve Myocardial Regeneration (ALLSTAR) Trial: Rationale and Design Cell Transplant. 2017 Feb 16;26(2):205-214 DOI: 10.3727/096368916X692933

Archibald P, Chandra A, Thomas D, Chose O, Massouridès E, Laâbi Y, Williams D Comparability of automated human induced pluripotent stem cell culture: a pilot study. Bioprocess Biosyst Eng. 2016; 39(12): 1847–1858. Published online 2016 Aug 8. doi:  10.1007/s00449-016-1659-9

Zimmermann JA, Hettiaratchi MH, McDevitt TC. Enhanced Immunosuppression of T Cells by Sustained Presentation of Bioactive Interferon-γ Within Three-Dimensional Mesenchymal Stem Cell Constructs. Stem Cells Translational Medicine. 2016; 5:1-15. Published online 8 Aug 2016; doi: 10.5966/sctm.2016-0044

Williams LB, Co C, Koenig JB, Tse C, Lindsay E, Koch TG Response to Intravenous Allogeneic Equine Cord Blood-Derived Mesenchymal Stromal Cells Administered from Chilled or Frozen State in Serum and Protein-Free Media. Frontiers in Veterinary Science. 2016; 3: 56. Published online 22 Jul 2016; doi: 10.3389/fvets.2016.00056

Camilleri ET, et al.  Identification and validation of multiple cell surface markers of clinical-grade adiposederived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production. Stem Cell Research & Therapy. (2016) 7:107.  DOI 10.1186/s13287-016-0370-8.

Wang X, Popplewell L, Wagner J, Naranjo A, Blanchard M, Mott M, Norris A, Wong C, Urak R, Chang W, Khaled S, Siddiqi T, Budde L, Xu J, Chang B, Gidwaney N, Thomas S, Cooper L, Riddell S, Brown C, Jensen M, Forman S. Phase 1 studies of central memory–derived CD19 CAR T–cell therapy following autologous HSCT in patients with B-cell NHL. BLOOD, 16 JUNE 2016 x VOLUME 127, NUMBER 24. DOI 10.1182/blood-2015-12-686725

Woods EJ, Thirumala S, Badhe-Buchanan SS, Clarke D, Mathew AJ. Off the shelf cellular therapeutics: Factors to consider during cryopreservation and storage of human cells for clinical use. (2016). Cytotherapy, June 2016, 18;(6), p697-711. DOI: https://dx.doi.org/10.1016/j.jcyt.2016.03.295.

Chapter Authors: Mandana Haack-Sorensen, Annette Ekblond, Jens Kastrup. Senior Editor: John M. Walker. Edited by: Massimiliano Gnecchi Cryopreservation and Revival of Human Mesenchymal Stromal Cells Mesenchymal Stem Cells Methods and Protocols, 2nd Edition (Methods in Molecular Biology Series). Chapter 21 – Cryopreservation and Revival of Human Mesenchymal Stromal Cells

Gramlich OW, Burand AJ, Brown AJ, Deutsch RJ, Kuehn MH, Ankruma JA. Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy. Scientific Reports. 2016; 6:26463. Published online 2016 May 23. doi:  10.1038/srep26463

Milani P, Escalante-Chong R, Shelley BC, Patel-Murray NL, Xin X, Adam M, Mandefro B, Sareen D, Svendsen CN, Fraenkel E.  Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells.  Scientific Reports. 2016; 6(1).  doi:10.1038/srep25474

Fritsch G, Frank N, Dmytrus J, Frech C, Pichler H, Witt V, Geyeregger R, Scharner D, Trbojevic D, Zipperer E, Printz D, Worel N. Relevance of flow cytometric enumberation of post-thaw leucocytes: influence of temperature during cell staining on viable cell recovery. Vox Sanguinis. (2016) April 1. doi: 10.1111/vox.12398. [Epub ahead of print]

Telezhkin V, Schnell C, Yarova P, Yung S, Cope E, et al. Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons. American Journal of Physiology – Cell Physiology Published 1 April 2016 Vol. 310 no. 7, C520-C541. DOI: 10.1152/ajpcell.00166.2015

Buckler, R. L., Kunkel, E. J., Thompson, M. L. and Ehrhardt, R. O.  Technological developments for small-scale downstream processing of cell therapies.  Cytotherapy. 2016; 18(3), 301-306.  doi: 10.1016/j.jcyt.2015.12.003

Safinia N, Vaikunthanathan T, Fraser H, Thirkell S, et al. Successful expansion of functional and stable regulatory T Cells for immunotherapy in liver transplantation. Onotarget, Advance Publications (2016) Feb 16;7(7);7563-77. doi: 10.18632/oncotarget.6927

Blazquez R, Sanchez-Margallo FM, Alvarez V, Uson A, Casado JG. Surgical meshes coated with mesenchymal stem cells provide an anti-inflammatory environment by a M2 macrophage polarization.  Acta Biomaterialia. 2016; 31(2); p221-230. doi: 10.1016/j.actbio.2015.11.057

Neves LS, Rodrigues MT, Reis RL, Gomes ME. Current approaches and future perspectives on strategies for the development of personalized tissue engineering therapies. Expert Review of Precision Medicine and Drug Development. Vol 1, Iss. 1, 2016. doi: 10.1080/23808993.2016.1140004

Guinan, E. C., Cole, G. A., Wylie, W. H., Kelner, R. H., Janec, K. J., Yuan, H., Oppatt, J., Brennan, L. L., Turka, L. A. and Markmann, J.  Ex Vivo Costimulatory Blockade to Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation.  American Journal Of Transplantation.  2016; 16(7), 2187-2195.  doi:10.1111/ajt.13725

Tseliou E, Kanazawa H, Dawkins J, Gallet R, Kreke M, Smith R, Middleton R, Valle J, Marbán L, Kar S, Makkar R, Marbán E Widespread Myocardial Delivery of Heart-Derived Stem Cells by Nonocclusive Triple-Vessel Intracoronary Infusion in Porcine Ischemic Cardiomyopathy: Superior Attenuation of Adverse Remodeling Documented by Magnetic Resonance Imaging and Histology PLoS One. 2016 Jan 19;11(1):e0144523 doi: 10.1371/journal.pone.0144523

Curbishley SM, Blahava M, Adams DH. Designing a dendritic cell-based therapy for primary liver cancer. MACS&more, Vol 17-1/2016

Fortin JM, Azari H, Zheng T, Darioosh RP, Schmoll, ME, Vedam-Mai V, Deleyrolle LP, Reynolds BA. Transplantation of Defined Populations of Differentiated Human Neural Stem Cell Progeny. Scientific Reports 6, Article number:23579 (2016). doi: 10.1038/srep23579

Singh N, Barnes SJ, Jenwithisuk R, Sattabongkot J, Adams JH. A simple and efficient method for cryopreservation and recovery of viable Plasmodium vivax and P. falciparum sporozoites. Parasitology International (2015) Epub 8 Dec 2015. doi:10.1016/j.parint.2015.12.003

Greene SJ, Epstein SE, Kim RJ, Quyyumi AA, Cole RT, Anderson AS, Wilcox JE, Skopicki HA, Sikora S, Verkh L, Tankovich NI, Gheorghiade M, Butler J. Rationale and design of a randomized controlled trial of allogeneic mesenchymal stem cells in patients with nonischemic cardiomyopathy. Journal of Cardiovascular Medicine, published ahead of print. doi: 10.2459/JCM.0000000000000303

Riegler J, Tiburcy M, Ebert A, Tzatzalos E, Raaz U, et al.  Human Engineered Heart Muscles Engraft and Survive Long-Term in a Rodent Myocardial Infarction Model .  Circulation Research. 2015 Sept 25; 117(8): 720-30.  DOI: 10.1161/CIRCRESAHA.115.306985.

Chen VC, Ye J, Shukla P, Hua G, Chen D, Lin Z, Liu J, Chai J. Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cells. Stem Cell Research, Volume 15, Issue 2, September 2015, 365–375. doi:10.1016/j.scr.2015.08.002

Marquez-Curtis, L. A., Janowska-Wieczorek, A., McGann, L. E. and Elliott, J. A.  Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects. Cryobiology.  2015; 71(2), 181-197.  doi: 10.1016/j.cryobiol.2015.07.003

Lee MC, Ha CW, Elmallah RK, Cherian JJ, Cho JJ, Kim TW, Bin SI, Mont MA. A placebo-controlled randomised trial to assess the effect of TGF-ß1-expressing chondrocytes in patients with arthritis of the knee. Bone Joint J. 2015 Jul;97-B(7):924-32 doi: 10.1302/0301-620X.97B7.35852

Hossain DMS, Pal SK, Moreira D, et al. TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients. Author manuscript published online first on May 12, 2015; DOI: 10.1158/1078-0432.CCR-14-3145

Oommen S, Yamada S, Peral SC, Campbell KA, Bruinsma ES, Terzic A, Nelson TJ Human umbilical cord blood-derived mononuclear cells improve murine ventricular function upon intramyocardial delivery in right ventricular chronic pressure overload. Stem Cell Research & Therapy. 2015;6(1):50. doi:10.1186/s13287-015-0044-y

Fernandes, P. et al. Canine helper-dependent vectors production: implications of Cre activity and co-infection on adenovirus propagation. Scientific Reports 5, Article number: 9135, 16 March 2015 doi:10.1038/srep09135

Peral SC, Burkhart HM, Oommen S, Yamada S, et al. Safety and Feasibility for Pediatric Cardiac Regeneration Using Epicardial Delivery of Autologous Umbilical Cord Blood-Derived Mononuclear Cells Established in a Porcine Model System. Stem Cells Tranl Med. 2015 Feb;4(2):195-206. doi: 10.5966/sctm.2014-0195. Epub 2015 Jan 5.

Lawal, Calvi. Osteolineage Notch Ligand Jagged1 Regulates Bone Homeostasis and Parathyroid Hormone-Dependent Long Term Hematopoietic Stem Cell Function. PhD Thesis, Department of Pathology and Laboratory Medicine, University of Rochester

Zhang et al. Sp1 and c-Myc modulate drug resistance of leukemia stem cells by regulating survivin expression through the ERK-MSK MAPK signaling pathway. Molecular Cancer (2015) 14:56 DOI 10.1186/s12943-015-0326-0

Hamot G, Ammerlaan W, Mathay C, Kofanova O, Betsou F. Method validation for automated isolation of viable peripheral blood mononuclear cells. Biopreservation and Biobanking, Vol. 13, No. 3, 2015. Mary Ann Liebert, Inc. DOI: 10.1089/bio.2014.0054

Fernandes P. Canine helper-dependent vectors production: implications of Cre activity and co-infection on adenovirus propagation. Scientific Reports 5, Article number: 9135, 16 March 2015 doi:10.1038/srep09135

AGE Day, Bhangra KS, Murray-Dunning C, Thanabalasundaram L, Grace N, Cameron G, Stevanato L, Sinden J, Phillips JB. Hypothermic and cryogenic preservation of artificial neural tissue made using differentiated CTX human neural stem cells in collagen gels. European Cells and Materials. Vol 29. Suppl. 3, (2015). Pg 44.

Podrazil M, Horvath R, Becht E, et al. Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer. (2015). Oncotarget, 5, 17891-17904.  DOI: 10.18632/oncotarget.4145

Nazari-Shafti, Bruno, Martinez, Coleman, Alt, McClure (2014). High Yield Recovery of Equine Mesenchymal Stem Cells from Umbilical Cord Matrix/Wharton’s Jelly Using a Semi-automated Process.  In Ivan N. Rich (ed.), Stem Cell Protocols: Springer Protocols, Methods in Molecular Biology, vol. 1235, DOI 10.1007/978-1-4939-1784-6, © Springer Science+Business Media New York 2015

Harper H, Rich I (2014). Measuring the Potency of a Stem Cell Therapeutic. In Ivan N. Rich (ed.), Stem Cell Protocols: Springer Protocols, Methods in Molecular Biology, vol. 1235, DOI 10.1007/978-1-4939-1784-6, © Springer Science+Business Media New York 2015

Charlene Geater. Direct Programming of Neural Progenitors into Medium Spiny Neurons by Transcription Factor Transfection. PhD Thesis (2014), Cardiff University

Ramos TV, Mathew AJ, Thompson ML, Ehrhardt RO. Standardized cryopreservation of human primary cells. (2014). Curr Protoc Cell Biol. 2014 Sep 2;64:A.3I.1-8. doi:10.1002/0471143030.cba03is64.

Eyrich M, et al. Development and validation of a fully GMP-compliant production process of autologous, tumor-lysate-pulsed dendritic cells. Cytotherapy – July 2014 (Vol. 16, Issue 7, Pages 946-964, DOI: 10.1016/j.jcyt.2014.02.017).

Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC. Selective Activity of the Histone Deacetylase Inhibitor AR-42 against Leukemia Stem Cells: A Novel Potential Strategy in Acute Myelogenous Leukemia. Mol Cancer Ther 2014;13:1979-1990. Published Online First June 16, 2014.

Zhu WZ, Van Biber B, Laflamme MA. Methods for the Derivation and Use of Cardiomyocytes from Human Pluripotent Stem Cells. Methods Mol Biol. Author manuscript; available in PMC Jun 4, 2014. Published in final edited form as: Methods Mol Biol. 2011; 767: 419–431. doi: 10.1007/978-1-61779-201-4_31

Kofanova Olga A., Davis Kristine, Glazer Barbara, De Souza Yvonne, Kessler Joseph, Betsou Fotini, and for the ISBER Biospecimen Science Working Group. Viable Mononuclear Cell Stability Study for Implementation in a Proficiency Testing Program: Impact of Shipment Conditions. Biopreservation and Biobanking. June 2014, 12(3): 206-216. doi:10.1089/bio.2013.0090.

Smith, Calvi. Osteoblastic VEGF Coordinates Remodeling of the Hematopoietic Stem Cell Niche. PhD Thesis, Department of Pathology and Laboratory Medicine, University of Rochester, 2014.

Kemppinen AK, Baker A, Liao W, et al. Exome sequencing in single cells from the cerebrospinal fluid in multiple sclerosis. Mult Scler 1352458514529613, first published on April 16, 2014 doi:10.1177/1352458514529613

Foussat A, Rietze R, Pottier E, et al. Effective Cryopreservation and Recovery of Human Regulatory T Cells. BioProcess International, Vol. 12, No. S3, March 2014, pp. 34–38.

Callahan KP, Minhajuddin M, Corbett C, Lagadinou ED, Rossi RM, Grose V, Balys MM, Pan L, Jacob S, Frontier A, Grever MR, Lucas DM, Kinghorn AD, Liesveld JL, Becker MW, Jordan CT.. Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity. Leukemia (28 February 2014) | doi:10.1038/leu.2014.93

Ikebe C, Suzuki K. Mesenchymal Stem Cells for Regenerative Therapy: Optimization of Cell Preparation Protocols. BioMed Research International, vol. 2014, Article ID 951512, 11 pages, 2014. doi:10.1155/2014/951512

Brandl C, Zimmermann SJ, Milenkovic VM, Rosendahl SM, Grassmann F, Milenkovic A, Hehr U, Federlin M, Wetzel CH, Helbiq H, Weber BH.. In-Depth Characterisation of Retinal Pigment Epithelium (RPE) Cells Derived from Human Induced Pluripotent Stem Cells (hiPSC). Neuromol Med (2014) 16:551–564 DOI 10.1007/s12017-014-8308-8

Ramos TV, Wang W, Okhovat J, McPherson G, Burger S. Human-derived raw materials: controlled, consistent collection and cryopreservation enable successful manufacturing of cell-based products. Cytotherapy , Volume 16 , Issue 4 , S103, DOI: https://dx.doi.org/10.1016/j.jcyt.2014.01.380

Feng Q, Shabrani N, Thon JN, Huo H, Thiel A, Machlus KR, Kim K, Brooks J, Li F, Luo C, Kimbrel EA, Want J, Kim K, Italiano J, Cho J, Lu S, Lanza R. Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells, Stem Cell Reports (2014), https://dx.doi.org/10.1016/j.stemcr.2014.09.010

Banas R, Miller C, Guzik L, Zeevi A. Amnion-Derived Multipotent Progenitor Cells Inhibit Blood Monocyte Differentiation Into Mature Dendritic Cells. Cell Transplantation, Volume 23, Number 9, 2014, pp. 1111-1125, https://dx.doi.org/10.3727/096368913X670165

Badraiq H, Devito L, Ilic D. Isolation and Expansion of Mesenchymal Stromal/Stem Cells from Umbilical Cord Under Chemically Defined Conditions. Methods in Molecular Biology, DOI 10.1007/7651_2014_116, © Springer Science+Business Media New York 2014

Yee K, Malliaras K, Kanazawa H, Tseliou E, Cheng K, Luthringer DJ, Ho CS, Takayama K, Minamino N, Dawkins JF, Chowdhury S, Duong DT, Seinfeld J, Middleton RC, Kharmakumar R, Li D, Marban L, Makkar RR, Marban E. Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy. PLoS ONE 9(12): e113805. doi:10.1371/journal.pone.0113805

White C, Benson K, Cherukuri P, Beals T. C-40: Cryobiology: Changing the face of regenerative medicine. Cryobiology; Volume 69, Issue 3, December 2014, Pages 511–512. doi:10.1016/j.cryobiol.2014.09.327

Clinton J, Shapiro B. Differentiation and expansion of hematopoietic precursor cells from bone-marrow derived CD34+ progenitors. (2014)  ATCC, AP Note 16

Safinia N, Lombardi G, Lechler R. An alliance with Miltenyi Biotec in the fight for tolerance: A venture into no man’s land. (2014). MACS & More, Vol 16, 1/2014, p. 11.

Senesac J, et al. (2014) Dendritic Cells Transfected with Adenoviral Vectors as Vaccines. In Michael J.P. Lawman and Patricia D. Lawman (eds.), Cancer Vaccines: Methods and Protocols, Methods in Molecular Biology, vol. 1139, DOI 10.1007/978-1-4939-0345-0_10, © Springer Science+Business Media New York 2014.

Kolodziej S, et al. PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation. Nat. Commun. 5:3995 doi: 10.1038/ncomms4995 (2014).

Michaud NR, Wang Y, McEachern K, et al. Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling. Mol Cancer Ther Published OnlineFirst December 16, 2013. doi:10.1158/1535-7163.MCT-13-0420

Vidigal, J., Fernandes, F., Coroadinha, A.S., Teixeira, A.P., Alves, P.M. Insect Cell Line Development Using Flp-Mediated Cassette Exchange Technology. In: Pörtner R. (eds) Animal Cell Biotechnology. Methods in Molecular Biology (Methods and Protocols). 2014; vol 1104. Humana Press, Totowa, NJ

Pei S, Minhajuddin M, Callahan KP, et al. Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells. JBC Papers in Press. Published on October 2, 2013 as Manuscript M113.511170 doi: 10.1074/jbc.M113.511170.

Malliaras, K., Smith, R. R., Kanazawa, H., Yee, K., Seinfeld, J., Tseliou, E., Dawkins, J. F., Kreke, M., Cheng, K., Luthringer, D., Ho, C., Blusztajn, A., Valle, I., Chowdhury, S., Makkar, R. R., Dharmakumar, R., Li, D., Marban, L. and Marban, E.  Validation of Contrast-Enhanced MRI to Monitor Regenerative Efficacy after Cell Therapy in a Porcine Model of Convalescent Myocardial Infarction.  Circulation. 2013 Dec 24; 128(25): 2764–2775.  doi: 10.1161/CIRCULATIONAHA.113.002863

Dannull J, Haley NR, Archer G, et al. Melanoma immunotherapy using mature DCs expressing the constitutive proteasome. J Clin Invest. 2013 July 1; 123(7): 3135–3145. Published online 2013 June 24. doi: 10.1172/JCI67544

Lagadinou ED, Sach A, Callahan K, Rossi RM, Neering SJ, et al. BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells. Science Direct. (2013) Volume 12, Issue 3, 7 March 2013, pps 329-341. 2013 doi:10.1016/j.stem.2012.12.013

Nettenstroma L, Alderson K, Raschke EE, Evans MD, Sondel PM, Olek S, Seroogy SML. An Optimized Multi-parameter Flow Cytometry Protocol for Human T Regulatory Cell Analysis on Fresh and Viably Frozen Cells, Correlation with Epigenetic Analysis, and Comparison of Cord and Adult Blood. Published in final edited form as: J Immunol Methods. 2013 January 31; 387(1-2): 81–88. doi:10.1016/j.jim.2012.09.014.

Pattasseril J, Varadaraju H, Lock L , Rowley JA. Downstream Technology Landscape for Large-Scale Therapeutic Cell Processing. (2013) BioProcess International, Vol. 11(3)s 38-47.

Hamy F. Controlled-Rate Freezing of Cells During Ultra Cold Transit. (2013) Fisher BioServices, Part of Thermo Fisher Scientific. Found here: Fisher BioServices

Parrish NF. Phenotypic Characteristics of Mucosally Transmitted Hiv-1. Publicaly Accessible Penn Dissertations, Paper 684 (2013)

Putnam AL, Safinia N, et al. Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation. American Journal of Transplantation 2013; XX: 1–11, Wiley Periodicals Inc. doi: 10.1111/ajt.12433

Zhou T, Benda C, Dunzinger S, Huang Y, Ho J.C, Yang J, Wang Y, Zhang Y, Zhuang Q, Li Y, Bao X, Tse H, Grillari J, Grillari-Voglauer R, Pei D, Esteban MA. Generation of human induced pluripotent stem cells from urine samples. Nature Protocols, 2012; Vol 7, No. 12, 280-289. Published online 8 November 2012; doi:10.1038/nprot.2012.115

Reynolds, Matthew R. ; Weiler, Andrea M.; Piaskowski, Shari M.; et al. A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection or control virus replication after a limiting-dose heterologous SIV challenge. Vaccine. 2012 June 22; 30(30): 4465–4475. doi:10.1016/j.vaccine.2012.04.082.

Gülen D, Maas S, Julius H, Warkentin P, Britton H, Younos I, Senesac J, Pirruccello SM, Talmadge JE. Cryopreservation of adenovirus-transfected dendritic cells (DCs) for clinical use. Int Immunopharmacol. 2012 May;13(1):61-8. doi: 10.1016/j.intimp.2012.03.009. Epub 2012 Mar 27.

Zhou Y, Fowler Z, Cheng A, Sever R. Improve Process Uniformity and Cell Viability in Cryopreservation. (2012) BioProcess International 1 Apr 2012.

Buffington DA, Pino CJ, Chen L, Westover AJ, Hageman G, Humes HD. Bioartificial Renal Epithelial Cell System (BRECS): A Compact, Cryopreservable Extracorporeal Renal Replacement Device. Cell Medicine, Vol. 4, pp. 33–43, 2012 2155-1790/12 $90.00. Printed in the USA. All rights reserved. DOI: https://dx.doi.org/10.3727/215517912X653328.

Frisch BJ, Ashton JM, Xing L , Becker MW, Jordan CT, Calvi LM. Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia. Published online before print September 28, 2011, doi: 10.1182/blood-2011-04-348151 Blood January 12, 2012 vol. 119 no. 2 540-550

Tobias Hofving. CD133 and ALDH1 as Prospective Markers for Cancer Stem Cells in Ileal Carcinoids

Turner R, Mendel G, Wauthier E, Barbier C, Reid LM. Hyaluronan-Supplemented Buffers Preserve Adhesion Mechanisms Facilitating Cryopreservation of Human Hepatic Stem/Progenitor Cells. CT-0574 Cell Transplantation Epub, provisional acceptance. DOI: 10.3727/096368912X637000

Tran C, Torres-Coronado M, Gardner A, Gu A, Vu H, Rao A, Cao IF, Ahmed A, Digiusto D. Optimized Processing of Growth Factor Mobilized Peripheral Blood CD34+ Products by Counterflow Centrifugal Elutriation. Stem Cells Translational Medicine 2012;1:422–429

Alexandre E, Baze A, Parmentier C, Desbans C, Pekthong D, Gerin B, Wack C, Bachellier P, Heyd B, Weber J, Richert L. Plateable cryopreserved human hepatocytes for the assessment of cytochrome P450 inducibility: experimental condition-related variables affecting their response to inducers. Xenobiotica, 2012; Early Online: 1–12. DOI: 10.3109/00498254.2012.676693

Li Y, Ma T. Bioprocessing of Cryopreservation for Large-Scale Banking of Human Pluripotent Stem Cells. BioResearch Open AccessVolume XX, Number XX, Month 2012, Mary Ann Liebert, Inc. DOI: 10.1089/biores.2012.0224

Wang X, Naranjo A, Brown CE, Bautista C, Wong CW, Chang W, Aguilar B, Ostberg JR, Riddell SR, Forman SJ, Jensen MC. Phenotypic and Functional Attributes of Lentivirus-modified CD19-specific Human CD8+ Central Memory T Cells Manufactured at Clinical Scale. Journal of Immunotherapy: November–December 2012; Volume 35, Issue 9, p 689–701, doi: 10.1097/CJI.0b013e318270dec7.

Jin S, Yao H, Weber JL, Melkoumian ZK, Ye K. A Synthetic, Xeno-Free Peptide Surface for Expansion and Directed Differentiation of Human Induced Pluripotent Stem Cells. PLoS ONE 7(11): e50880. doi:10.1371/journal.pone.0050880. (November 2012)

João Miguel Nunes Vidigal. Development of an insect cell factory for the production of complex biopharmaceuticals using a synthetic biology approach. Master’s Thesis (2011), University of Lisbon

Acosta FL, Metz L, Adkisson HD, et al.  Porcine Intervertebral Disc Repair Using Allogeneic Juvenile Articular Chondrocytes or Mesenchymal Stem Cells. Tissue Engineering Part A. 2011;17(23-24):3045-3055.  doi:10.1089/ten.tea.2011.0229.

Moulick, Ahn, Zong, Rodina, Cerchietti, DaGama, Caldas-Lopes, Beebe, Perna, Hatzi, Vu, Zhao, Zatorska,Taldone, Smith-Jones, Alpaugh, Gross, Pillarsetty, Ku, Lewis, Larson, Levine, Erdjument-Bromage, Guzman, Nimer, Melnick, Neckers, Chiosis. Affinity-Based Proteomics Reveal Cancer-Specific Networks Coordinated by Hsp90. Nat Chem Biol. 2011 Sep 25; 7(11): 818–826. Published online 2011 Sep 25. doi: 10.1038/nchembio.670

Rios M. Optimizing Cryopreservation for Therapeutic Cells. BioProcess International, Vol. 9, No. 4, April 2011, pp. 26–30

Fritsch G, Witt V, Matthes S, Dworzak M, Artwohl M, Clarke D, Mathew AJ. Improved Post-Thaw Stability Validation of Peripheral Blood Cell Products Utilizing the Intracellular-Like Cryostor Cryopreservation Solution, and Preliminary Results of Clinical Application. Biology of Blood and Marrow Transplantation. February 2011; Volume 17, Issue 2, S210-S211.

Woods EJ, Thirumala S. Packaging Considerations for Biopreservation Transfusion Medicine and Hemotherapy. 2011; 38(2): 149–156.

Nicoud IA, Clarke DM, Taber G, Stolowski KM, Roberge SE, Song MK, Mathew AJ, Reems J. Cryopreservation of umbilical cord blood with a novel freezing solution that mimics intracellular ionic composition. Transfusion. doi: 10.1111/j.1537-2995.2011.03547.x

Lai-Hipp C, Goldberg T, Scott E, Ziman A, Vyas G. Pooled peripheral blood mononuclear cells provide an optimized cellular substrate for human immunodeficiency virus Type 1 isolation during acute infection. Transfusion 51: 333-337 (February 2011)

Engelhardt BG, Jagasia M, Savani BN, Bratcher NL, et at.  Regulatory T cell expression of CLA or α4β7 and skin or gut acute GVHD outcomes Bone Marrow Transplantation (2011) 46, 436–442; doi:10.1038/bmt.2010.127; published online 31 May 2010.

Chacon L, Gomez M, Jenkins J, Leibo S, Wirtu G, Dresser B, Pope C. Effect of cryopreservation and in vitro culture of bovine fibroblasts on histone acetylation levels and in vitro development of hand-made cloned embryos. Zygote 19 (August), pp. 255–264. DOI: 10.1017/S0967199410000316

Murphy S, Rosli S, Acharya R, Mathias L, Lim R, Wallace E, Jenkin G. Amnion Epithelial Cell Isolation and Characterization for Clinical Use. Current Protocols in Stem Cell Biology. June, 2010. UNIT 1E.6.

Malpique R, Osório LM, Ferreira DS, Ehrhart F, Brito C, Zimmermann H, Alves PM. Alginate Encapsulation as a Novel Strategy for the Cryopreservation of Neurospheres. Tissue Eng Part C Methods. 2010 Feb 8.

Mathew A.J. I’m Losing Cell Viability and Function at Different Points in My Process, and I Don’t Know Why! BioProcess International, 8 (6): 54-7 (2010).

Kim AJ, Adkisson HD, Wendland M, Seyedin M, Berven S, Lotz JC. Juvenile Chondorcytes May Facilitate Disc Repair (2010) The Open Tissue Engineering and Regenerative Medicine Journal, 2010, 3, 28-35.

Hessel A, Schwendinger M, Fritz D, Coulibaly S, Holzer GW, et al.  A Pandemic Influenza H1N1 Live Vaccine Based on Modified Vaccinia Ankara Is Highly Immunogenic and Protects Mice in Active and Passive Immunizations. (2010) PLoS ONE 5(8): e12217. doi:10.1371/journal.pone.0012217.

Valentine LE, Loffredo JT, Bean AT, León EJ, MacNair CE, Beal DR, Piaskowski SM, Klimentidis YC, Lank SM, Wiseman RW, Weinfurter JT, May GE, Rakasz EG, Wilson NA, Friedrich TC , O’Connor DH, Allison DB, Watkins DI. Infection with “Escaped” Virus Variants Impairs Control of Simian Immunodeficiency Virus SIVmac239. Journal of Virology, November 2009, p. 11514-11527, Vol. 83, No. 22. Copyright © 2009, American Society for Microbiology.

Clarke DM, Yadock DJ, Nicoud IB, Mathew AJ, Heimfeld S. Improved post-thaw recovery of peripheral blood stem/progenitor cells using a novel intracellular-like cryopreservation solution.  Cytotherapy. 2009;11(4):472-9. doi: 10.1080/14653240902887242.

Luckett-Chastain LR, Gallucci RM. Interleukin (IL)-6 Modulates Transforming Growth Factor-β Expression in Skin and Dermal Fibroblasts from IL-6-Deficient Mice. Br J Dermatol. 2009 August; 161(2): 237–248.

Chacon L, Gomez M, Jenkins J, Leibo S, Wirtu G, Dresser B, Pope C. Production of bovine cloned embryos with donor cells frozen at a slow cooling rate in a conventional freezer (−20 °C). Zygote: pp. 1-11. doi:10.1017/S0967199409005474

Güll I, Alves PM, Gabor F, Wirth M. Viability of the Human Adenocarcinoma Cell Line Caco-2: Influence of Cryoprotectant, Freezing Rate, and Storage Temperature. Sci Pharm. 2009; 77: 133–141.

Malpique R, Ehrhart F, Katsen-Globa A, Zimmermann H, Alves PM. Cryopreservation of Adherent Cells: Strategies to Improve Cell Viability and Function after Thawing. Tissue Engineering: Part C, Volume 15, Number 00, 2009.

Thirumala S, Goebel WS, Woods EJ. Clinical Grade Adult Stem Cell Banking. Organogenesis. 2009 Jul–Sep; 5(3): 143–154. © 2009 Landes Bioscience.

Woods EJ, et al. Optimized cryopreservation method for human dental pulp-derived stem cells and their tissues of origin for banking and clinical use. Cryobiology. 2009 Oct;59(2):150-7. DOI:10.1016/j.cryobiol.2009.06.005.

Perry BC, Zhou D, Wu X, Yang FC, Byers MA, Chu G, Hockema JJ, Woods EJ, Goebel WS. Collection, Cryopreservation, and Characterization of Human Dental Pulp–Derived Mesenchymal Stem Cells for Banking and Clinical Use. Tissue Engineering Part C: Methods. June 2008, 14(2): 149-156. doi:10.1089/ten.tec.2008.0031.

Ennis J, Sarugaser R, Gomez A, Baksh D, Davies JE. Isolation, Characterization, and Differentiation of Human Umbilical Cord Perivascular Cells (HUCPVCs). Methods in Cell Biology. 2008; Vol. 86, 121-136.