Cryopreservation
Freeze Media
Our library of independent research demonstrates the effectiveness of BioLife Solutions’ products.
Over 600 independent research projects show how BioLife Solutions products improve sample viability.
Over 600 Articles, Abstracts and Posters Citing the Use of CryoStor and HypoThermosol.
Hundreds of articles have been written about the use of our products, CryoStor and HypoThermosol. Learn more about our products’ use in the cell and gene therapy industry, or ask one of our scientists a question directly.
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Journal Articles
Abstracts
Posters
Domingues, S., Darle, A., Masson, Y., Saidani, M., Lagoutte, E., Bejanariu, A., Coutier, J., Ayata, R. E., Bouschbacher, M., Peschanski, M., Lemaitre, G. and Baldeschi, C. Clinical Grade Human Pluripotent Stem Cell-Derived Engineered Skin Substitutes Promote Keratinocytes Wound Closure In Vitro. Cells. 2022; 11(7), 1151. doi: 10.3390/cells11071151
Iwata, Y., Narushima, Y., Harada, A. and Mishima, M. Priming treatment with T-cell redirecting bispecific antibody ERY974 reduced cytokine induction without losing cytotoxic activity in vitro by changing the chromatin state in T cells. Toxicology And Applied Pharmacology. 2022; 441, 115986. doi: 10.1016/j.taap.2022.115986
Thongsin, N. and Wattanapanitch, M. A three-dimensional immune-oncology model for studying in vitro primary human NK cell cytotoxic activity. PLOS ONE. 2022; 17(3), e0264366. doi: 10.1371/journal.pone.0264366
Aisha Naeem, Nikita Gupta, Natasha Arzoo, Usra Naeem, Muhammad Jawad Khan, Muhammad Umer Choudhry, Wanxing Cui and Chris Albanese. A Survey and Critical Evaluation of Isolation, Culture, and Cryopreservation Methods of Human Amniotic Epithelial Cells. Cell Cycle. 2022. doi: 10.1080/15384101.2021.2020015
Olivarria, G. M., Cheng, Y., Furman, S., Pachow, C., Hohsfield, L. A., Smith-Geater, C., Miramontes, R., Wu, J., Burns, M. S., Tsourmas, K. I., Stocksdale, J., Manlapaz, C., Yong, W. H., Teijaro, J., Edwards, R., Green, K. N., Thompson, L. M. and Lane, T. E. Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice. Journal Of Virology. 2022; 96(4). doi: 10.1128/jvi.01969-21
DeVeaux, S. A., Ogle, M. E., Vyshnya, S., Chiappa, N. F., Leitmann, B., Rudy, R., Day, A., Mortensen, L. J., Kurtzberg, J., Roy, K. and Botchwey, E. A. Characterizing human mesenchymal stromal cells’ immune-modulatory potency using targeted lipidomic profiling of sphingolipids. Cytotherapy. 2022. doi: 10.1016/j.jcyt.2021.12.009
Capelli, C., Frigerio, S., Lisini, D., Nava, S., Gaipa, G., Belotti, D., Cabiati, B., Budelli, S., Lazzari, L., Bagnarino, J., Tanzi, M., Comoli, P., Perico, N., Introna, M. and Golay, J. A comprehensive report of long-term stability data for a range ATMPs: A need to develop guidelines for safe and harmonized stability studies. Cytotherapy. 2022. doi: 10.1016/j.jcyt.2021.12.004
Vogelzang, N. J., Beer, T. M., Gerritsen, W., Oudard, S., Wiechno, P., Kukielka-Budny, B., Samal, V., Hajek, J., Feyerabend, S., Khoo, V., Stenzl, A., Csöszi, T., Filipovic, Z., Goncalves, F., Prokhorov, A., Cheung, E., Hussain, A., Sousa, N., Bahl, A., Hussain, S., Fricke, H., Kadlecova, P., Scheiner, T., Korolkiewicz, R. P., Bartunkova, J., Spisek, R., Stadler, W., Berg, A. S., Kurth, K., Higano, C. S., Aapro, M., Krainer, M., Hruby, S., Meran, J., Polyakov, S., Machiels, J., Roumeguere, T., Ackaert, K., Lumen, N., Gil, T., Minchev, V., Tomova, A., Dimitrov, B., Koleva, M., Juretic, A., Fröbe, A., Vojnovic, Z., Drabek, M., Jarolim, L., Buchler, T., Kindlova, E., Schraml, J., Zemanova, M., Prausova, J., Melichar, B., Chodacka, M., Jansa, J., Daugaard, G., Delonchamps, N., Duclos, B., Culine, S., Deplanque, G., Le Moulec, S., Hammerer, P., Rodemer, G., Ritter, M., Merseburger, A., Grimm, M., Damjanoski, I., Wirth, M., Burmester, M., Miller, K., Herden, J., Keck, B., Wuelfing, C., Winter, A., Boegemann, M., von Schmeling, I. K., Fornara, P., Jaeger, E., Bodoky, G., Pápai, Z., Böszörményi-Nagy, G., Vanella, P., SotoParra, H., Passalacqua, R., Ferrau, F., Maio, M., Fratino, L., Cortesi, E., Purkalne, G., Asadauskiene, J., Janciauskiene, R., Tulyte, S., Cesas, A., Polee, M., Haberkorn, B., van de Eertwegh, F., van den Berg, P., Beeker, A., Nieboer, P., Zdrojowy, R., Staroslawska, E., Fijuth, J., Sikora-Kupis, B., Karaszewska, B., Fernandes, I., Sousa, G., Rodrigues, T., Dzamic, Z., Babovic, N., Cvetkovic, B., Sokol, R., Mikuláš, J., Gajdos, M., Brezovsky, M., Mincik, I., Breza, J., Arranz, J. A., Calvo, V., Rubio, G., Chapado, M. S., Boreu, P. G., Montesa, A., Olmos, D., Mellado, B., Castellano, D., Puente, J., Karlsson, E. T., Ahlgren, J., Pandha, H., Mazhar, D., Vilarino-Varela, M., Elliott, T., Pedley, I., Zarkar, A., Law, A., Slater, D., Karlin, G., Bilusic, M., Redfern, C., Gaur, R., McCroskey, R., Clarkson, D., Agrawal, M., Shtivelband, M., Nordquist, L., Karim, N., Hauke, R., Flaig, T., Jhangiani, H., Singal, R., Choi, B., Reyes, E., Corman, J., Hwang, C., Appleman, L., McClay, E., Fleming, M., Gunuganti, V., Cheung, E., Gartrell, B., Sartor, A., Williamson, S., Gandhi, J., Schnadig, I., Burke, J., Bloom, S., Shore, N., Mayer, T., Oh, W., Bryce, A., Belkoff, L., Vaishampayan, U., Agarwala, S., Kucuk, O., Agrawal, A., Walsh, W., Poiesz, B., Harshman, L., Dawson, N. and Sharma, S. Efficacy and Safety of Autologous Dendritic Cell–Based Immunotherapy, Docetaxel, and Prednisone vs Placebo in Patients With Metastatic Castration-Resistant Prostate Cancer – The VIABLE Phase 3 Randomized Clinical Trial. JAMA Oncology. 2022. doi: 10.1001/jamaoncol.2021.7298
Fear, V. S., Forbes, C. A., Anderson, D., Rauschert, S., Syn, G., Shaw, N., Jamieson, S., Ward, M., Baynam, G. and Lassmann, T. CRISPR single base editing, neuronal disease modelling and functional genomics for genetic variant analysis: pipeline validation using Kleefstra syndrome EHMT1 haploinsufficiency. Stem Cell Research & Therapy. 2022; 13(1). doi: 10.1186/s13287-022-02740-3
Bifani, A. M., Tan, H. C., Choy, M. M., and Ooi, E. E. Cell Strain-Derived Induced Pluripotent Stem Cells as an Isogenic Approach To Investigate Age-Related Host Response to Flaviviral Infection. Journal of Virology. 2022; 96(3). doi: 10.1128/jvi.01737-21
Kakon, N., Luizaga, H., Pham, C., Bezabih, R., Elnour, H., Procter, J., Ping, J., Highfill, S., Stroncek, D. F., Panc, S. R. Comparable Postthaw CD34+ and CD3+ Cell Characteristics With Commercial and In-House Cryoprotectants: Commercial Favored for Ease of Use. Transfusion. 2019; 59(S3), 106A-107A. doi:10.1111/trf.15462
Lee, Tsung (John) Dao. A Comprehensive Review of Umbilical Cord Cryopreservation: Umbilical Cord Tissue Banking Cryopreserved Technology and Standard Operating Procedure. Transfusion Vol. 58, 2018 Supplement. Pages 4A-5Av.
Clark, E., Stasko, K., and Paciulan, B. A COMPARISON STUDY OF CURRENT FREEZING MEDIA VERSUS CRYOSTOR10 FOR CRYOPRESERVATION OF QC VIALS. Cytotherapy. May 2018; 20(5), S62. doi.org/10.1016/j.jcyt.2018.02.173
Pasha, Elmoazzen, Pineault. Development and testing of a stepwise thaw and dilute protocol for cryopreserved umbilical cord blood units.Transfusion. 2017 Jul;57(7):1744-1754. doi: 10.1111/trf.14136
Biunno I, Ntai A. Banking of Human Pluripotent Stem Cells. Biopreservation and Biobanking Volume 15, Number 3, 2017. DOI:10.1089=bio.2017.29021.abstracts
Fink J, Abazari A, Hawkins B, Albert M, O’Donnell K, Mathew A. Best Practices vs. Traditional Practices of Procedures and Technology for Preserving Viability and Functionality of T-Cells at Both -80 C and -190 C. Biopreservation and Biobanking Volume 15, Number 3, 2017. DOI:10.1089=bio.2017.29021.abstracts
Abazari A. Biopreservation considerations in the evolving field of cellular therapies. Cryobiology Volume 73, Issue 3, December 2016, Page 399. https://doi.org/10.1016/j.cryobiol.2016.09.007
de Vries M, Broeren MGA, Bennink MB, et al. A10.08 Detailed analysis of the effect of cryopreservation on the viability and cytokine release of human synovial tissue. Annals of the Rheumatic Diseases 2016; 75:A75-A76. doi:10.1136/annrheumdis-2016-209124.180.
Gramlich OW, Zhu W, Burand A, Ankrum JA, et al. Transplantation of cryopreserved MSC rescues retinal ganglion cells following I/R injury. ARVO 2016 Annual Meeting Abstracts (2016).
Fearnot ER, Fazekasova H, Thirkell S, Lowe K, Bushell A, Lombardi G. C-25: Evaluation of closed system medical device for low volume storage for clinical studies involving regulatory T cells. Cryobiology (2014). Volume 69, Issue 3, December 2014. Pages 508. doi:10.1016/j.cryobiol.2014.09.312