Hypothermic Storage & Shipping Media
Our library of independent research demonstrates the effectiveness of BioLife Solutions’ products.
Over 600 independent research projects show how BioLife Solutions products improve sample viability.
Over 600 Articles, Abstracts and Posters Citing the Use of CryoStor and HypoThermosol.
Hundreds of articles have been written about the use of our products, CryoStor and HypoThermosol. Learn more about our products’ use in the cell and gene therapy industry, or ask one of our scientists a question directly.
Presentation
Journal Articles
Abstracts
Posters
Won, T., Wood, M. K., Hughes, D. M., Talor, M. V., Ma, Z., Schneider, J., Skinner, J. T., Asady, B., Goerlich, E., Halushka, M. K., Hays, A. G., Kim, D., Parikh, C. R., Rosenberg, A. Z., Coppens, I., Johns, R. A., Gilotra, N. A., Hooper, J. E., Pekosz, A. and Čiháková, D. Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs. Ebiomedicine. 2022; 75, 103812. doi: 10.1016/j.ebiom.2022.103812
Erol, O. D., Pervin, B., Seker, M. E. and Aerts-Kaya, F. Effects of storage media, supplements and cryopreservation methods on quality of stem cells. World Journal Of Stem Cells. 2021; 13(9), 1197-1214. doi: 10.4252/wjsc.v13.i9.1197
Ciervo, Y., Gatto, N., Allen, C., Grierson, A., Ferraiuolo, L., Mead, R. J. and Shaw, P. J. Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS. Molecular Therapy – Methods & Clinical Development. 2021 Mar 27; 21:413-433. doi: 10.1016/j.omtm.2021.03.017
Ścieżyńska, A., Soszyńska, M., Szpak, P., Krześniak, N., Malejczyk, J. and Kalaszczyńska, I. Influence of Hypothermic Storage Fluids on Mesenchymal Stem Cell Stability: A Comprehensive Review and Personal Experience. Cells. 2021; 10(5), 1043. doi: 10.3390/cells10051043
Nam, Y., Yoon, D., Hong, J., Kim, M. S., Lee, T. Y., Kim, K. S., Lee, H., Suk, K. and Kim, S. R. Therapeutic Effects of Human Mesenchymal Stem Cells in a Mouse Model of Cerebellar Ataxia with Neuroinflammation. Journal Of Clinical Medicine. 2021; 9(11), 3654. doi: 10.3390/jcm9113654
Todd CJ Berard, Aby J Mathew. Biopreservation and cold chain biologistics risk points in the cell and gene therapy workflow. Cell & Gene Therapy Insights 2020; 6(08), 1363–1380. doi: 10.18609/cgti.2020.150
Singh, S., Chakravarty, T., Chen, P., Akhmerov, A., Falk, J., Friedman, O., Zaman, T., Ebinger, J. E., Gheorghiu, M., Marbán, L., Marbán, E. and Makkar, R. R. Allogeneic cardiosphere-derived cells (CAP-1002) in critically ill COVID-19 patients: compassionate-use case series. Basic Research In Cardiology. 2020; 115(4). doi: 10.1007/s00395-020-0795-1
Mund, S. J. K., Kawamura, E., Awang-Junaidi, A. H., Campbell, J., Wobeser, B., MacPhee, D. J., Honaramooz, A. and Barber, S. Homing and Engraftment of Intravenously Administered Equine Cord Blood-Derived Multipotent Mesenchymal Stromal Cells to Surgically Created Cutaneous Wound in Horses: A Pilot Project. Cells. 2020; 9(5), 1162. doi: 10.3390/cells9051162
Menon, R., Otto, E. A., Hoover, P. J., Eddy, S., Mariani, L. H., Godfrey, B., Berthier, C. C., Eichinger, F., Subramanian, L., Harder, J. L., Ju, W., Nair, V., Larkina, M., Naik, A. S., Luo, J., jain, S., Sealfon, R., Troyanskaya, O. G., Hacohen, N., Hodgin, J. B. and Kretzler, M. Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker. JCI Insight. 2020; 5(6):e133267. doi:10.1172/jci.insight.133267
Madissoon, E., Wilbrey-Clark, A., Miragaia, R. J., Saeb-Parsy, K., Mahbubani, K. T., Georgakopoulos, N., Harding, P., Polanski, K., Huang, N., Nowicki-Osuch, K., Fitzgerald, R. C., Loudon, K. W., Ferdinand, J. R., Clatworthy, M. R., Tsingene, A., van Dongen, S., Dabrowska, M., Patel, M., Stubbington, M. J. T., Teichmann, S. A., Stegle, O. and Meyer, K. B. scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation. Genome Biology. 2020; 21(1). doi: 10.1186/s13059-019-1906-x
Abazari A. Biopreservation considerations in the evolving field of cellular therapies. Cryobiology Volume 73, Issue 3, December 2016, Page 399. https://doi.org/10.1016/j.cryobiol.2016.09.007
Liotta A, Sandersen C, Ceusters J, Girod M, Peeters D, Bolen G. Computed tomography-guided injection of muscle-derived mesenchimal stem cells in the intervertebral disc of dogs affected by natural disc degeneration: clinical safety and intervertebral disc imaging assessment.
Rossetti T, Nichols F, Modo M. Intracerebral Cell Implantation: Preparation and Characterization of Cell Suspensions. Cell Transplant. 2016;25(4):645-664. doi: 10.3727/096368915X690350
Herias M. Investigation of HypoThermosol® as a delivery medium for cardiomyocyte progenitor cells. Cytotherapy 16(4):S38 (2014). DOI: http://dx.doi.org/10.1016/j.jcyt.2014.01.130
Honaramooz, Yang. Isolation of Porcine Testis Cells from Fresh and Preserved Tissues. Biology of Reproduction, Volume 81, Issue Suppl_1, 1 July 2009, Page 688. https://doi.org/10.1093/biolreprod/81.s1.688
Snyder KK, Baust JM, Van Buskirk RG, Baust JG. Improved Hypothermic Storage of Sensitive Primary Cell Systems. Cytotherapy, Vol. 7 Supp. 1, pg. 2, 2005.
Snyder KK, Baust JM, Van Buskirk RG, Baust JG. Assessment of Function and Metabolic Activity of Neonatal Cardiomyocytes Following Hypothermic Storage. Cryobiology, Vol. 47 No. 3, pg. 273, 2003. (P.L. Steponkus Crystal Award Recipient)
Mathew AJ, Baust JG, Van Buskirk RG. Enhanced hypothermic preservation of multiple human cell types. Cryobiology 43:383 (2001).
Mathew AJ, Baust JG, Van Buskirk RG. Enhanced hypothermic preservation of human renal cells. Cryobiology 43:357 (2001).
Mathew, AJ, Baust JM, Hollister WR, Al-Abdullah IH, Ricordi C, Van Buskirk RG, Baust JG. Molecular biological analysis of cell death leads to improvement in the hypothermic solution, HypoThermosol. Cryobiology 41:335-6 (2000).
