Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism

Horie, S., Gaynard, S., Murphy, M., Barry, F., Scully, M., O’Toole, D. and Laffey, J. G.  Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism.  Intensive Care Medicine Experimental. 2020; 8(1).  doi: 10.1186/s40635-020-0295-5

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Assessment of Immune Response Following Dendritic Cell-Based Immunotherapy in Pediatric Patients With Relapsing Sarcoma

Fedorova, L., Mudry, P., Pilatova, K., Selingerova, I., Merhautova, J., Rehak, Z., Valik, D., Hlavackova, E., Cerna, D., Faberova, L., Mazanek, P., Pavelka, Z., Demlova, R., Sterba, J., Zdrazilova-Dubska, L.  Assessment of Immune Response Following Dendritic Cell-Based Immunotherapy in Pediatric Patients With Relapsing Sarcoma.  Frontiers in Oncology. 2019; 9.  doi:10.3389/fonc.2019.01169

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Pre‐clinical development of a cryopreservable megakaryocytic cell product capable of sustained platelet production in mice

Patel, A., Clementelli, C. M., Jarocha, D., Mosoyan, G., Else, C., Kintali, M., Fong, H., Tong, J., Gordon, R., Gillespie, V., Keyzner, A., Poncz, M., Hoffman, R., Iancu‐Rubin, C.  Pre‐clinical development of a cryopreservable megakaryocytic cell product capable of sustained platelet production in mice.  Transfusion. 2019; 59(12), 3698-3713.  doi: 10.1111/trf.15546

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CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions

Jung, J., Buisman, S. C., Weersing, E., Dethmers-Ausema, A., Zwart, E., Schepers, H., Dekker, M. R., Lazare, S. S., Hammerl, F., Skokova, Y., Kooistra, S. M., Klauke, K., Poot, R. A., Bystrykh, L. V., de Haan, G. CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions. Cell…

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BioPreservation Blog 1/30/2019

Disease models facilitate understanding the pathogenesis of disease, identification and development of potential interventions and evaluation of new treatments. BioLife Solutions maintains an online, searchable, Evidence Library that contains over 365 articles, abstracts and posters citing Biopreservation efficacy of CryoStor® and HypoThermosol®. Recently added to the Evidence Library, the journal article authored by Xinyue Bai…

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Identification of Pre-Existing Adaptive Immunity to Cas9 Proteins in Humans

Charlesworth, C. T., Deshpande, P. S., Dever, D. P., Camarena, J., Lemgart, V. T., Cromer, M. K., Vakulskas, C. A., Collingwood, M. A., Zhang, L., Bode, N. M., Behlke, M. A., Dejene, B., Cieniewicz, B., Romano, R., Lesch, B. J., Gomez-Ospina, N., Mantri, S., Pavel-Dinu, M., Weinberg, K. I., Porteus, M. H.  Identification of Pre-Existing…

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