CRISPR single base editing, neuronal disease modelling and functional genomics for genetic variant analysis: pipeline validation using Kleefstra syndrome EHMT1 haploinsufficiency

Fear, V. S., Forbes, C. A., Anderson, D., Rauschert, S., Syn, G., Shaw, N., Jamieson, S., Ward, M., Baynam, G. and Lassmann, T. CRISPR single base editing, neuronal disease modelling and functional genomics for genetic variant analysis: pipeline validation using Kleefstra syndrome EHMT1 haploinsufficiency. Stem Cell Research & Therapy. 2022; 13(1). doi: 10.1186/s13287-022-02740-3

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SARS-CoV-2 can infect and propagate in human placenta explants

Fahmi, A., Brügger, M., Démoulins, T., Zumkehr, B., Oliveira Esteves, B.I., Bracher, L., Wotzkow, C., Blank, F., Thiel, V., Baud, D., Alves, M.P. SARS-CoV-2 can infect and propagate in human placenta explants. Cell Reports Medicine. 2021; 100456. doi: 10.1016/j.xcrm.2021.100456

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Transcription Factor Programming of Human Pluripotent Stem Cells to Functionally Mature Astrocytes for Monocultures and Cocultures with Neurons

Quist E., Ahlenius H., and Canals I.  Transcription Factor Programming of Human Pluripotent Stem Cells to Functionally Mature Astrocytes for Monocultures and Cocultures with Neurons.  In: Ahlenius H. (eds) Neural Reprogramming. Methods in Molecular Biology. 2021; vol 2352, pp. 133-148. Humana, New York, NY.  doi: 10.1007/978-1-0716-1601-7_10

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Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different times show comparable biological functions in vitro, and in vivo to repair limb ischemia

Thej, C., Balasubramanian, S., Rengasamy, M., Walvekar, A., Swamynathan, P., Raj, S. S., Shahani, P., Siddikuzzaman, Kolkundkar, U., Seetharam, R. N., Gupta, P. K. and Majumdar, A. S.  Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different times show comparable biological functions in vitro, and in vivo to repair limb…

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