ex vivo Archives | BioLife Solutions

Stem-cell-derived human microglia transplanted into mouse brain to study human disease

Fattorelli, N., Martinez-Muriana, A., Wolfs, L., Geric, I., De Strooper, B. and Mancuso, R. Stem-cell-derived human microglia transplanted into mouse brain to study human disease. Nature Protocols. 2021. doi: 10.1038/s41596-020-00447-4

Ex vivo-expanded highly pure ABCB5+ mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data

Kerstan, A., Niebergall-Roth, E., Esterlechner, J., Schröder, H. M., Gasser, M., Waaga-Gasser, A. M., Goebeler, M., Rak, K., Schrüfer, P., Endres, S., Hagenbusch, P., Kraft, K., Dieter, K., Ballikaya, S., Stemler, N., Sadeghi, S., Tappenbeck, N., Murphy, G. F., Orgill, D. P., Frank, N. Y., Ganss, C., Scharffetter-Kochanek, K., Frank, M. H. and Kluth, M.…

Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood

Motwani, K., Peters, L. D., Vliegen, W. H., El-sayed, A. G., Seay, H. R., Lopez, M. C., Baker, H. V., Posgai, A. L., Brusko, M. A., Perry, D. J., Bacher, R., Larkin, J., Haller, M. J. and Brusko, T. M. Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability…

Improving T-cell expansion and function for adoptive T-cell therapy using ex vivo treatment with PI3Kδ inhibitors and VIP antagonists

Petersen, Hassan, Morris, Jeffery, Lee, Jagirdar, Staton, Raikar, Spencer, Sulchek, Flowers, Waller. Improving T-cell expansion and function for adoptive T-cell therapy using ex vivo treatment with PI3Kδ inhibitors and VIP antagonists. Blood Advances 2018 2:210-223. DOI 10.1182/bloodadvances.2017011254

Ex Vivo-expanded Natural Killer Cells Derived From Longterm Cryopreserved Cord Blood are Cytotoxic Against Primary Breast Cancer Cells

Nham, Poznanski, Fan, Vahedi, Shenouda, Lee, Chew, Hogg, Lee, Ashlar. Ex Vivo-expanded Natural Killer Cells Derived From Longterm Cryopreserved Cord Blood are Cytotoxic Against Primary Breast Cancer Cells. Journal of Immunotherapy: Post Author Corrections: November 17, 2017. doi: 10.1097/CJI.0000000000000192

Preclinical development of an automated injection device for intradermal delivery of a cell-based therapy

Giulia Leoni, Alex Lyness, Patrick Ginty, Rindi Schutte, Gopalan Pillai, Gayatri Sharma, Paul Kemp, Natalie Mount, Michaela Sharpe. Preclinical development of an automated injection device for intradermal delivery of a cell-based therapy. Drug Delivery and Translational Research. (2017) 7:695–708. doi: 10.1007/s13346-017-0418-z

Effects of ultraprofound hypothermia on the ex vivo contractile response of cerebral arteries: Relevance to cerebrovascular dysfunction during cardiopulmonary bypass.

Wagerle LC, Taylor MJ, Dahdah NS, Russo P. Effects of ultraprofound hypothermia on the ex vivo contractile response of cerebral arteries: Relevance to cerebrovascular dysfunction during cardiopulmonary bypass. Cryobiology 35:346 (1997).

Functional survival of isolated rabbit hearts after cold storage in HypoThermosol modified with compounds that might promote retention and repletion of high energy phosphates.

Taylor MJ, Snyder M, Machen L, Clark RE, Baust JG. Functional survival of isolated rabbit hearts after cold storage in HypoThermosol modified with compounds that might promote retention and repletion of high energy phosphates. Cryobiology 33:620-1, (1996).

The importance of adenosine and glutathione as components of a new hypothermic blood substitute (HypoThermosol): Evaluation of myocardial protection at 7°C using an isolated working rabbit heart model.

Taylor MJ, Clark RE, Baust JG. The importance of adenosine and glutathione as components of a new hypothermic blood substitute (HypoThermosol): Evaluation of myocardial protection at 7°C using an isolated working rabbit heart model. Cryobiology 30:593-4 (1994).