A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials

Henrieta Fraser, Niloufar Safinia ,Nathali Grageda, Sarah Thirkell, Katie Lowe, Laura J. Fry, Cristiano Scottá, Andrew Hope, Christopher Fisher, Rachel Hilton, David Game, Paul Harden, Andrew Bushell, Kathryn Wood, Robert I. Lechler, Giovanna Lombardi.  A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials.  Molecular Therapy: Methods & Clinical Development 2018…

Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease

Huang, Khan, Au, Barber, López-Vásquez, Prokopishyn, Boutin, Rothe, Rip, Abaoui, Nagree, Dworski, Schambach, Keating, West, Klassen, Turner, Sirrs, Rupar, Auray-Blais, Foley, Medin. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease. Molecular Therapy: Methods & Clinical Development Vol. 5 June 2017. doi:  10.1016/j.omtm.2017.05.003

Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis

Fraser, Pass, Burgoyne, Atkinson, Bailey, Laurie, McGowan, Hamid, Moore, Dwyer, Turner, Forbes, Campbell. Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis. CytoTherapy – The Journal of Cell Therapy; Article in Press. DOI: http://dx.doi.org/10.1016/j.jcyt.2017.05.009

Banking of Human Pluripotent Stem Cells

Biunno I, Ntai A. Banking of Human Pluripotent Stem Cells. Biopreservation and Biobanking Volume 15, Number 3, 2017. DOI:10.1089=bio.2017.29021.abstracts