Ex vivo-expanded highly pure ABCB5+ mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data

Kerstan, A., Niebergall-Roth, E., Esterlechner, J., Schröder, H. M., Gasser, M., Waaga-Gasser, A. M., Goebeler, M., Rak, K., Schrüfer, P., Endres, S., Hagenbusch, P., Kraft, K., Dieter, K., Ballikaya, S., Stemler, N., Sadeghi, S., Tappenbeck, N., Murphy, G. F., Orgill, D. P., Frank, N. Y., Ganss, C., Scharffetter-Kochanek, K., Frank, M. H. and Kluth, M.…

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Pancreas-derived mesenchymal stromal cells share immune response-modulating and angiogenic potential with bone marrow mesenchymal stromal cells and can be grown to therapeutic scale under Good Manufacturing Practice conditions

Thirlwell, K. L., Colligan, D., Mountford, J. C., Samuel, K., Bailey, L., Cuesta-Gomez, N., Hewit, K. D., Kelly, C. J., West, C. C., McGowan, N. W., Casey, J. J., Graham, G. J., Turner, M. L., Forbes, S. and Campbell, J. D.  Pancreas-derived mesenchymal stromal cells share immune response-modulating and angiogenic potential with bone marrow mesenchymal…

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In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials

Tappenbeck, N., Schröder, H. M., Niebergall-Roth, E., Hassinger, F., Dehio, U., Dieter, K., Kraft, K., Kerstan, A., Esterlechner, J., Frank, N. Y., Scharffetter-Kochanek, K., Murphy, G. F., Orgill, D. P., Beck, J., Frank, M. H., Ganss, C., Kluth, M. A.  In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for…

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