CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells

Kluesner, M., Lahr, W., Lonetree, C., Smeester, B., Qiu, X., Slipek, N., Vázquez, P., Pitzen, S., Pomeroy, E., Vignes, M., Lee, S., Bingea, S., Andrew, A., Webber, B. and Moriarity, B.  CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells.  Nature Communications. 2021; 12(1), 1-12.  doi.:…

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Characterisation of circulating tumour cell phenotypes identifies a partial-EMT sub-population for clinical stratification of pancreatic cancer

Semaan, A., Bernard, V., Kim, D. U., Lee, J. J., Huang, J., Kamyabi, N., Stephens, B. M., Qiao, W., Varadhachary, G. R., Katz, M. H., Shen, Y., San Lucas, F. A., Gascoyne, P., Alvarez, H. A., Maitra, A. and Guerrero, P. A.  Characterisation of circulating tumour cell phenotypes identifies a partial-EMT sub-population for clinical stratification…

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