An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity

Carbonneau, S., Sharma, S., Peng, L., Rajan, V., Hainzl, D., Henault, M., Yang, C., Hale, J., Shulok, J., Tallarico, J., Porter, J., Brogdon, J., Dranoff, G., Bradner, J. E., Hild, M. and Guimaraes, C. P.  An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity.  Cell Chemical Biology. 2020.  doi: 10.1016/j.chembiol.2020.11.012

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CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions

Jung, J., Buisman, S. C., Weersing, E., Dethmers-Ausema, A., Zwart, E., Schepers, H., Dekker, M. R., Lazare, S. S., Hammerl, F., Skokova, Y., Kooistra, S. M., Klauke, K., Poot, R. A., Bystrykh, L. V., de Haan, G. CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions. Cell…

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