preclinical Archives | Page 2 of 4

Liaskou, E., Patel, S. R., Webb, G., Bagkou Dimakou, D., Akiror, S., Krishna, M., Mells, G., Jones, D. E., Bowman, S. J., Barone, F., Fisher, B. A. and Hirschfield, G. M. Increased sensitivity of Treg cells from patients with PBC to low dose IL-12 drives their differentiation into IFN-γ secreting cells. Journal Of Autoimmunity (2018). doi:10.1016/j.jaut.2018.07.020

Clinical Cellular Therapeutics Accelerate Clot Formation

George, M. J., Prabhakara, K., Toledano-Furman, N. E., Wang, Y., Gill, B. S., Wade, C. E., Olson, S. D. and Cox, C. S. Clinical Cellular Therapeutics Accelerate Clot Formation. STEM CELLS Translational Medicine (2018). doi:10.1002/sctm.18-0015

Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue

Donlin, L. T., Rao, D. A., Wei, K., Slowikowski, K., McGeachy, M. J., Turner, J. D., Meednu, N., Mizoguchi, F., Gutierrez-Arcelus, M., Lieb, D. J., Keegan, J., Muskat, K., Hillman, J., Rozo, C., Ricker, E., Eisenhaure, T. M., Li, S., Browne, E. P., Chicoine, A., Sutherby, D., Noma, A., Nusbaum, C., Kelly, S., Pernis, A.…

Development of in vitro enteroids derived from bovine small intestinal crypts

Hamilton, C. A., Young, R., Jayaraman, S., Sehgal, A., Paxton, E., Thomson, S., Katzer, F., Hope, J., Innes, E., Morrison, L. J. and Mabbott, N. A. Development of in vitro enteroids derived from bovine small intestinal crypts. Veterinary Research. 2018; 49(1). doi:10.1186/s13567-018-0547-5

Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons.

Fernandopulle, M., Prestil, R., Grunseich, C., Wang, C., Gan, L., Ward, M. Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons. Current Protocols In Cell Biology 2018; 79(1), e51. doi:10.1002/cpcb.51

Discogenic cell transplantation directly from a cryopreserved state in an induced intervertebral disc degeneration canine model

Hiraishi, S., Schol, J., Sakai, D., Nukaga, T., Erickson, I., Silverman, L., Foley, K., Watanabe, M. Discogenic cell transplantation directly from a cryopreserved state in an induced intervertebral disc degeneration canine model. JOR Spine. (2018); 1(2), e1013. doi:10.1002/jsp2.1013

Discogenic cell transplantation directly from a cryopreserved state in an induced intervertebral disc degeneration canine model

Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA–Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy

Hung, C., Xu, X., Li, L., Ma, Y., Jin, Q., Viley, A., Allen, C., Natarajan, P., Shivakumar, R., Peshwa, M. V. and Emens, L. A. Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA–Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy. Human Gene Therapy. 2018; 29(5), 614-625. doi:10.1089/hum.2017.080

Inflammatory and stem-like colorectal cancer (CRC) subtypes identified in patient-derived xenograft (PDX) models show tumor growth inhibition (TGI) by the combination of trametinib (T) and neratinib (N) irrespective of KRAS mutation (MT) status

Inflammatory and stem-like colorectal cancer (CRC) subtypes identified in patient-derived xenograft (PDX) models show tumor growth inhibition (TGI) by the combination of trametinib (T) and neratinib (N) irrespective of KRAS mutation (MT) status

Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment

Wagner, J., Kline, C. L., Zhou, L., Campbell, K. S., MacFarlane, A. W., Olszanski, A. J., Cai, K. Q., Hensley, H. H., Ross, E. A., Ralff, M. D., Zloza, A., Chesson, C. B., Newman, J. H., Kaufman, H., Bertino, J., Stein, M., El-Deiry, W. S. Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral…