An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity

Carbonneau, S., Sharma, S., Peng, L., Rajan, V., Hainzl, D., Henault, M., Yang, C., Hale, J., Shulok, J., Tallarico, J., Porter, J., Brogdon, J., Dranoff, G., Bradner, J. E., Hild, M. and Guimaraes, C. P.  An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity.  Cell Chemical Biology. 2020.  doi: 10.1016/j.chembiol.2020.11.012

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Identification of Pre-Existing Adaptive Immunity to Cas9 Proteins in Humans

Charlesworth, C. T., Deshpande, P. S., Dever, D. P., Camarena, J., Lemgart, V. T., Cromer, M. K., Vakulskas, C. A., Collingwood, M. A., Zhang, L., Bode, N. M., Behlke, M. A., Dejene, B., Cieniewicz, B., Romano, R., Lesch, B. J., Gomez-Ospina, N., Mantri, S., Pavel-Dinu, M., Weinberg, K. I., Porteus, M. H.  Identification of Pre-Existing…

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