An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity

Carbonneau, S., Sharma, S., Peng, L., Rajan, V., Hainzl, D., Henault, M., Yang, C., Hale, J., Shulok, J., Tallarico, J., Porter, J., Brogdon, J., Dranoff, G., Bradner, J. E., Hild, M. and Guimaraes, C. P.  An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity.  Cell Chemical Biology. 2020.  doi: 10.1016/j.chembiol.2020.11.012

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Single-cell atlas of colonic CD8+ T cells in ulcerative colitis

Corridoni, D., Antanaviciute, A., Gupta, T., Fawkner-Corbett, D., Aulicino, A., Jagielowicz, M., Parikh, K., Repapi, E., Taylor, S., Ishikawa, D., Hatano, R., Yamada, T., Xin, W., Slawinski, H., Bowden, R., Napolitani, G., Brain, O., Morimoto, C., Koohy, H. and Simmons, A.  Single-cell atlas of colonic CD8+ T cells in ulcerative colitis.  Nature Medicine.  2020; 26(9),…

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