Di Giorgio, E., Wang, L., Xiong, Y., Akimova, T., Christensen, L. M., Han, R., Samanta, A., Trevisanut, M., Bhatti, T. R., Beier, U. H. and Hancock, W. W. Mef2d sustains activation of effector Foxp3+ Tregs during transplant survival and anticancer immunity. Journal Of Clinical Investigation. 2020. doi: 10.1172/jci135486
Read MoreCorridoni, D., Antanaviciute, A., Gupta, T., Fawkner-Corbett, D., Aulicino, A., Jagielowicz, M., Parikh, K., Repapi, E., Taylor, S., Ishikawa, D., Hatano, R., Yamada, T., Xin, W., Slawinski, H., Bowden, R., Napolitani, G., Brain, O., Morimoto, C., Koohy, H. and Simmons, A. Single-cell atlas of colonic CD8+ T cells in ulcerative colitis. Nature Medicine. 2020. doi:…
Read MoreSu, T., Ying, Z., Lu, X., He, T., Song, Y., Wang, X., Ping, L., Xie, Y., Tu, M., Liu, G., Qi, F., Ding, Y., Jing, H. and Zhu, J. The clinical outcomes of fresh versus cryopreserved CD19-directed chimeric antigen receptor T cells in non-Hodgkin lymphoma patients. Cryobiology. 2020. doi: 10.1016/j.cryobiol.2020.07.009
Read MoreTrzupek, D., Dunstan, M., Cutler, A. J., Lee, M., Godfrey, L., Jarvis, L., Rainbow, D. B., Aschenbrenner, D., Jones, J. L., Uhlig, H. H., Wicker, L. S., Todd, J. A. and Ferreira, R. C. Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis. Genome Medicine. 2020; 12(1). …
Read MoreSanteramo, I., Bagnati, M., Harvey, E.J., Hassan, E., Surmacz-Cordle, B., Marshall, D., Di Cerbo, V. Vector copy distribution at a single cell level enhances analytical characterisation of gene-modified cell therapies. Molecular Therapy – Methods & Clinical Development. 2020; 17, 944-956. doi: 10.1016/j.omtm.2020.04.016.
Read MoreMotwani, K., Peters, L. D., Vliegen, W. H., El-sayed, A. G., Seay, H. R., Lopez, M. C., Baker, H. V., Posgai, A. L., Brusko, M. A., Perry, D. J., Bacher, R., Larkin, J., Haller, M. J. and Brusko, T. M. Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability…
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Cryopreservation adds flexibility to timelines when working with cells. In the case of cellular therapies, that can mean initial flexibility to schedule patient cell collection, transport cells to the manufacturing facility and initiate manufacturing. Cryopreservation of the final cell therapy product adds flexibility to be able to schedule the return of cells to the patient…
Read MoreHanna, S. J., Powell, W. E., Long, A. E., Robinson, E. J. S., Davies, J., Megson, C., Howell, A., Jones, T. J., Ladell, K., Price, D. A., Dayan, C. M., Williams, A. J. K., Gillespie, K. M. and Wong, F. S. Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet…
Read MoreLam, N., Trinklein, N., Buelow, B., Patterson, G., Ojha, N., Kochenderfer, J. Anti-BCMA chimeric antigen receptors with fully human heavy-chain-only antigen recognition domains. Nature Communications. 2020; 11(1). doi: 10.1038/s41467-019-14119-9
Read MoreMadissoon, E., Wilbrey-Clark, A., Miragaia, R. J., Saeb-Parsy, K., Mahbubani, K. T., Georgakopoulos, N., Harding, P., Polanski, K., Huang, N., Nowicki-Osuch, K., Fitzgerald, R. C., Loudon, K. W., Ferdinand, J. R., Clatworthy, M. R., Tsingene, A., van Dongen, S., Dabrowska, M., Patel, M., Stubbington, M. J. T., Teichmann, S. A., Stegle, O. and Meyer, K.…
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