A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials

Henrieta Fraser, Niloufar Safinia ,Nathali Grageda, Sarah Thirkell, Katie Lowe, Laura J. Fry, Cristiano Scottá, Andrew Hope, Christopher Fisher, Rachel Hilton, David Game, Paul Harden, Andrew Bushell, Kathryn Wood, Robert I. Lechler, Giovanna Lombardi.  A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials.  Molecular Therapy: Methods & Clinical Development 2018…

Pathologically expanded peripheral T helper cell subsets drives B cells in rheumatoid arthritis

Rao, Gurish, Marshall, Slowikowski, Fonseka, Liu, Donlin, Henderson, Wei, MizoGuchi, Teslovich, Weinblatt, Massarotti, Coblyn, Helfgott, Lee, Todd, Bykerk, Goodman, Pernis, Ivashkiv, Karlson, Nigrovic, Filer, Buckley, Lederer, Raychaudhuri, Brenner. Pathologically expanded peripheral T helper cell subsets drives B cells in rheumatoid arthritis. Nature 542, 110–114 (02 February 2017) doi:10.1038/nature20810