Dynamic chromatin regulatory landscape of human CAR T cell exhaustion

Gennert, D. G., Lynn, R. C., Granja, J. M., Weber, E. W., Mumbach, M. R., Zhao, Y., Duren, Z., Sotillo, E., Greenleaf, W. J., Wong, W. H., Satpathy, A. T., Mackall, C. L. and Chang, H. Y.  Dynamic chromatin regulatory landscape of human CAR T cell exhaustion.  Proceedings Of The National Academy Of Sciences. 2021;…

Read More

c-Jun overexpression in CAR T cells induces exhaustion resistance

Lynn, R. C., Weber, E. W., Sotillo, E., Gennert, D., Xu, P., Good, Z., Anbunathan, H., Lattin, J., Jones, R., Tieu, V., Nagaraja, S., Granja, J., de Bourcy, C. F. A., Majzner, R., Satpathy, A. T., Quake, S. R., Monje, M., Chang, H. Y. and Mackall, C. L.  c-Jun overexpression in CAR T cells induces…

Read More