Rigid CGT
Container
CellSeal® CryoCase
The next generation cell and gene therapy container
The CellSeal CryoCase is the first ever cryo-compatible rigid container designed for closed-system fill and retrieval for larger volumes of fluid (<75 mL). The container is transparent, enabling improved end user compliance with USP 790, USP 1790, and other international visible inspection methods.
CellSeal CryoCase is manufactured under strict environmental and processing controls designed to limit common sources of particulates in single-use disposable manufacturing.
Testing has shown viability equivalency with existing bags for multiple cell types.
- Versatile fill volumes: 25 mL, 50 mL, and 75 mL
- Exterior dimensions (sealed, H x W x D): 136 mm x 136 mm x 14 mm
- Weight (sealed without fill lines): 74 g
- Material: COC; Spike ports: EVA
- XL fill line for easier sterile welding.
- Built-in spike ports for closed-system retrieval.
- Transparent, glass-like structure for improved inspectability.
- Rigid design with inherent dampening mechanisms to protect samples during handling.
- Convenient hanger mechanism to engage with fill machines, bag poles or other laboratory equipment.
- Designed to minimize particulate contamination and enhance the safety and performance of cryopreserved cell therapies.
- Tested to demonstrate superior durability, leak-proof construction, and fracture resistance when compared to cryobags.
- Evaluated for equivalent performance in terms of cell viability and recovery, ensuring consistent results without compromising on safety.
- Developed to simplify the cryopreservation process and eliminate the need for multiple operators and additional steps like air evacuation, making it a more efficient and user-friendly alternative to cryobags.
- Evidence of comparable freezing and thawing rates between the CellSeal CryoCase and traditional cryobags.
- Clear for improved inspectability, ensuring better particulate detection, essential for ensuring the quality of cell and gene therapies.
Please download CellSeal CryoCase resources here:
Rethink the standard.
Replace the bag.
Flexible and closed fluid management system
Use the Signata CT-5® platform for final fill, media formulation, and bioreactor fill and wash. As a fluid transfer system, the Signata CT-5 allows reversible flow direction from up to 11 input/output points and three-way control valves allowing closed movement between multiple points. The CellSeal CryoCase was designed to be compatible with this system.
