Vials for
Automated Filling
CellSeal® Cryovial
Closed-system cryogenic vials for CGT manufacturing
CellSeal® Cryogenic Vials are the first purpose-built rigid containers used in the cell and gene therapy industry. Unlike traditional screw cap vials and stoppered vials, the hermetically sealed access ports withstand the challenges of -196°C storage without compromising container closure integrity (CCI).
With a full suite of accessories and filling systems, vials can be filled manually or with high throughput systems – ideal for both autologous and allogeneic products.
- 5mL and 2mL vial sizes
- Swabbable or capped Luer-compatible fill ports
- USP Class VI compliant materials
- Certificate of Compliance per lot provided with each purchase
- Cryogenic vials can be safely handled when frozen.
- Designed for extreme temperature conditions.
- Closed-system design prevents sample leakage.
- Microbial barrier vent for filling and withdrawal at atmospheric pressure.
- Conically-shaped retrieval port for maximum sample recovery.
- Loading ports configured for syringes, pipettes, or needleless Luer fittings.
- Compatible with the Signata CT-5 Fluid Management System.
Please download CellSeal Cryogenic Vial resources here:
Frequently Asked Questions
CellSeal Vials are validated in actual conditions. CellSeal Vials were subjected to freezing, storage in liquid nitrogen (LN2), a drop test, frozen transportation, and thawing. Following thawing, a series of container integrity tests were performed, including dye and bacterial immersion studies. All vials met the defined criteria for each test.
All specimen contacting materials are manufactured from USP Class VI compliant materials, and have been subjected to biological safety testing that included genotoxicity, cytotoxicity, sensitization, irritation, hemocompatibility, and acute systemic toxicity.
Yes. A Certificate of Compliance per lot number is provided to the customer with each purchase.
CellSeal Vials have demonstrated low levels of extractables during a leachables study.
The CellSeal Vial has an expiration date of three years from date of manufacture.
Please refer to the product instructions in the resource section above on how to use CellSeal Cryogenic Vials.
The expansion profile of different solutions are dependent on content, concentration and freezing process. We suggest evaluating the expansion profile of your product in CellSeal Vials under the intended conditions of use. Please contact us for additional information.
ThawSTAR® CSV 2/5
Automated Thawing System, designed for use with CellSeal® Vials
Are you still using a manual water bath to thaw vials? Frustrated by inconsistent thaw profiles and cell viability?
Check out the ThawSTAR® CSV 2 and ThawSTAR® CSV 5 Automated Thawing Systems, now available for CellSeal Cryogenic Vials and CellSeal Connect Vials.
- ~3 min thaw time
- Water-free
- Qualifiable
- Programmed precision
- Safer samples
Please download ThawSTAR CSV 2/5 resources here:
