The History of Cryopreservation

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Cryopreservation: From Home-Brew to Cutting-Edge Solutions In the pursuit of medical breakthroughs, technology often emerges from the drive to fulfill critical needs. This is particularly evident in the field of cryopreservation, where a convergence of technological advances seeks to preserve therapeutic cells for a myriad of applications, from treating human afflictions to aiding animals in […]

Empowering Your Downstream Cell and Gene Therapy Processes: A Sexton Biotechnologies Focus

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BioLife Solutions acquired Sexton Biotechnologies to better serve the needs of cell and gene therapy (CGT) developers and manufacturers. Sexton complements BioLife’s existing portfolio by offering media to improve cell performance and cell expansion, automated and flexible fluid transfer manufacturing equipment, and modern CGT storage containers for closed-system processing. Sexton tools can advance your downstream […]

How to Choose the Right Freeze Media 

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The process of cryopreservation, which has been carried out for decades, is a crucial aspect of cell preservation for various scientific endeavors — from experimental research to clinical applications. While the fundamental process involves freezing cells and storing them at ultra-low or cryogenic temperatures, the choice of cryopreservation media plays a pivotal role in ensuring […]

The Evolution of Cell and Gene Therapy Processing Tools

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01/ Borrowed tools from other industries Prior to the invention of gene therapy research, the removal, storage and reinsertion of human cell tissue was limited to blood. The logistical and technical challenges were minimal. However, scientists quickly discovered that maintaining the integrity and transparency of autologous and allogeneic cells throughout extraction, storage, transportation, delivery and […]

Sexton Biotechnologies to be Acquired by Biolife Solutions

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Sexton Biotechnologies, a provider of novel manufacturing solutions for the cell and gene therapy (CGT) industry, today announced that it has entered into a definitive agreement whereby BioLife Solutions (NASDAQ: BLFS) will acquire all outstanding shares of the company in a deal worth a total value of $30 million. During the past two years, Sexton has worked to provide […]

The Number of FDA-Approved Autologous CAR T Cell Therapies Continues to Grow

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Bristol Myers Squibb’s Breyanzi Receives FDA Approval. Breyanzi is Cryopreserved in CryoStor® CS10.  Earlier this year, the U.S. Food and Drug Administration published a press release announcing the approval of CD19-targeting CAR T cell therapy, Breyanzi (lisocabtagene maraleucel; liso-cel). Breyanzi is approved to treat adult patients with relapsed or refractory large B-cell lymphoma that has not responded following “two or more […]

Journal Articles Citing CryoStor CS10® Recently Added to BioLife Solutions’ Evidence Library

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Multiple Uses for CryoStor in Cell Manufacturing Journal articles recently added to BioLife Solutions’ Evidence Library illustrate several stages during the cell manufacturing process for which CryoStor CS10® cryopreservation solution is applicable. The three articles that follow include several different cell types cryopreserved in CryoStor CS10. An expanded list of cell types biopreserved in BioLife […]

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