AF-500 Automated Fill and Seal System

High-throughput fill and seal system for use with CellSeal cryogenic vials

Automated Fill and Seal System

AF-500 Automated Fill and Seal System

AF500 Automated Fill and Seal System Product Image

From concept to commercialization, the CealSeal AF-500 delivers the automation difference in a precision engineered and GMP compatible fill-finish system. For cell and gene therapy developers and manufacturers, the AF-500 provides the path to scale up and standardize through increased accuracy, speed, and productivity. Its versatile design for controlled environments include benchtops, biosafety cabinets, or an isolator.


  • Fill System dimensions: 117.5 cm wide x 50.7 cm high x 50 cm deep
  • Electronic control cabinet dimensions: 60 cm wide x 45.1 cm high x 21 cm deep
  • Fill System weight: 95 kgs
  • Electrical cabinet weight: 30 kgs
  • Electricity: Voltage: 120 / 230V+PE, Electrical Power: 120V / 8A (60Hz), 230V / 5A (50Hz)


  • Cryogenic Vials can be safely handled when frozen
  • Designed for extreme temperature conditions
  • Closed-system design prevents sample leakage
  • Microbial barrier vent for filling and withdrawal at atmospheric pressure
  • Conically-shaped retrieval port for maximum sample recovery
  • Loading ports configured for syringes, pipettes, or needleless Luer fittings
  • Compatible with off-the-shelf Sexton fill systems


For use in biosafety cabinets or isolators

Compatible with vaporized hydrogen peroxide sterilization

Please download AF-500 Data Sheet brochure here:

Sexton Biotechnologies

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BioLife Solutions Inc.
3303 Monte Villa Parkway,
Suite 310, Bothell , WA 98021 USA

For assistance, please call us Monday
through Friday (9:00 am to 5:00 pm PST) at:

Toll Free (North America): +1.866.424.6543
Direct: +1.425.402.1400
Fax: +1.425.402.1433

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